Climbazole

ChemicalBook > CAS DataBase List > Climbazole

Risks to the environment

Product Name: Climbazole
CAS No.: 38083-17-9
Chemical Name: Climbazole
Synonyms: CLIMBAZOL;baypival;Crinipan AD;1-[(4-Chlorophenoxy)(tert-butylcarbonyl)Methyl]iMidazole;1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one;BAYSAN;MEB-6401;climbazo;bay-e6975;Diadimefon
CBNumber: CB8671477
Molecular Formula: C15H17ClN2O2
Formula Weight: 292.76
MOL File: 38083-17-9.mol

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Climbazole Property

Melting point:: 96-100°C
Boiling point:: 447.5±40.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
vapor pressure: 0.001Pa at 25℃
refractive index: 1.54
storage temp.: Inert atmosphere,Room Temperature
solubility: Insoluble in water
form: Solid
pka: 5.66±0.22(Predicted)
color: White to Almost white
Water Solubility: 58mg/L at 25℃
BRN: 618020
InChIKey: OWEGWHBOCFMBLP-UHFFFAOYSA-N
LogP: 3.83 at 25℃
CAS DataBase Reference: 38083-17-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-50/53
Safety Statements: 60-61
RIDADR: UN 3077
WGK Germany: 3
RTECS: EL7085000
HS Code: 29332900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 36127
Product name: Climbazole
Purity: PESTANAL?, analytical standard
Packaging: 100mg
Price: $106
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1135600
Product name: Climbazole
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 400mg
Price: $436
Updated: 2024/03/01

TCI Chemical

Product number: C2025
Product name: Climbazole
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $60
Updated: 2024/03/01

TCI Chemical

Product number: C2025
Product name: Climbazole
Purity: >98.0%(HPLC)(T)
Packaging: 500g
Price: $483
Updated: 2024/03/01

Cayman Chemical

Product number: 27968
Product name: (±)-Climbazole
Packaging: 50g
Price: $78
Updated: 2024/03/01

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Climbazole Chemical Properties,Usage,Production

Risks to the environment

Climbazole (CBZ) is an emerging recalcitrant contaminant in wastewater, which has severe toxic effects on aquatic organisms.

Description

(±)-Climbazole is an imidazole antifungal agent. It inhibits the growth of C. albicans (MIC = 0.29 μg/ml), as well as clinical isolates of M. pachydermatis (MICs = <0.06-1 μg/ml) and M. furfur (MICs = <0.06-0.5 μg/ml) in vitro. It also reduces the size of Malassezia populations on the skin of naturally infected dogs when used at a dose of 2% in shampoo. (±)-Climbazole (80 mg/kg) increases the levels of cytochrome P450 in rat liver. Formulations containing climbazole have been used in the treatment of dandruff.

Chemical Properties

White Solid

Uses

Climbazole is an imidazole antifungal agent that can provide anti-dandruff benefits when incorporated into a shampoo matrix. s assay and did not induce micronuclei in human lymphocytes.

Definition

ChEBI: 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one is a ketone that is butan-2-one substituted by a 4-chlorophenoxy and a 1H-imidazol-1-yl group at position 1 and 2 methyl groups at position 3. It is a member of monochlorobenzenes, a member of imidazoles, an aromatic ether, a ketone and a hemiaminal ether.

Hazard

Moderately toxic by ingestion. Low toxicity by skin contact.

Flammability and Explosibility

Non flammable

Side effects

May cause localized irritation of the skin with symptoms including redness, rashes and itching.

Climbazole Preparation Products And Raw materials

Raw materials

3-Thiophenezoic acid Imidazole Pyrazole

Preparation Products

Methidathion

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Climbazole Suppliers

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View Lastest Price from Climbazole manufacturers

BLiT (Hefei)Chemical Co.,Ltd

Product: Climbazole 38083-17-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100TONS
Release date: 2024-03-27

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Climbazole 38083-17-9
Price: US $120.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-29

Hebei Saisier Technology Co., LTD

Product: Climbazole 38083-17-9
Price: US $6.00/KG
Min. Order: 1KG
Purity: More than 99%
Supply Ability: 2000KG/MONTH
Release date: 2024-04-18

38083-17-9, ClimbazoleRelated Search:

Imidazole Dimethyl sulfide N,N-Dimethylformamide Dimethyl sulfoxide 1-Vinylimidazole Dimethyl phthalate Dimethyl fumarate Dimethyl ether 4-Methyl-2-pentanone 2-Butanone oxime ETHANE Tetra-(methylethylketoxime)silane Dimethyldimethoxysilane 1-AMINO-3,3-DIMETHYL-BUTAN-2-ONE 1-AMINO-3,3-DIMETHYL-BUTAN-2-ONE HYDROCHLORIDE PHENOXYACETONE 1-(4-CHLOROPHENOXY)-2-PROPANONE 2-Propanone, 1-(1H-imidazol-1-yl)- (9CI)

1-(4-Chloro-phenoxy)-1-(2,5-dihydro-imidazole-1-yl)-3,3-dimethyl-butan-2-one

1-(4-chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutanone

BAY MEB-6401

Diadimefon

MEB-6401

Climbazole 0.1

1-[(4-Chlorophenoxy)(tert-butylcarbonyl)Methyl]iMidazole

Crinipan AD

1-(p-chlorophenoxy)-3,3-dimethyl-1-(1-imidazolyl)-2-butanon

1-(p-chlorophenoxy)-3,3-dimethyl-1-(1-imidazolyl)-2-Butanone

Climbazole (400 mg)

Climbazol Solution, 100ppm

climbazole:1-(4-clorophenoxy)-3,3-dimethyl-1-(IMIDAZOLE-1-yl)-2-butanone

Active climbazole

1-(4-Chlorophenoxy)-1-(1-imidazolyl)-3,3-dimethyl-2-butanone

bay-e6975

baypival

RadixAsteris

BAYSAN

CLIMBAZOL

CLIMBAZOLE

1-(4-clorophenoxy)-3,3-dimethyl-1-(imidazole-1-yl)-2-butanone

1-(4-CHLOROPHENOXY)-1-(1 H-IMIDAZOL-1-YL)-3,3-DIMETHYLBUTANONE

1-(4-CHLOROPHENOXY)-1-(IMIDAZOL-1-YL)-3,3-DIMETHYL-2-BUTANONE

1-(4-Chloro-phenoxy)-1-imidazol-1-yl-3,3-dimethyl-butan-2-one

CLIMBAZOL PESTANAL 250 MG

CLIMBAZOL PESTANAL<TM>

1-(4-Chlorophenoxy)-3,3-dimethyl-1-imidazole-1-yl)-2-butone

1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-2-butanone

2-Butanone, 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-

climbazole (ban)

1-(4-clorophenoxy)-3,3-dimethyl-1-(imidazole-1-yl)-2-butano

1-(4-Chlorophenoxy)-3,3-dimethyl-1-imidazole-1-yl)-2-butone(climbazole)

Climbazole &gt

Climbazol,Climbazole,Radix Asteris

1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one

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