1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE

Product Name: 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
CAS No.: 129487-92-9
Chemical Name: 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
Synonyms: 1-Boc-5-aMinoindoline;5-AMINO-1-BOC-2,3-DIHYDROINDOLE;1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE;1-Boc-2,3-dihydro-1H-indol-5-amine;tert-Butyl 5-aMinoindoline-1-carboxylate;2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate;tert-butyl 5-amino-2,3-dihydroindole-1-carboxylate;tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate;5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester
CBNumber: CB8683580
Molecular Formula: C13H18N2O2
Formula Weight: 234.29
MOL File: 129487-92-9.mol

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1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Property

Boiling point:: 385.2±41.0 °C(Predicted)
Density: 1.177±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 5.44±0.20(Predicted)
form: liquid
color: Brown

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Safety

HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T205238
Product name: tert-Butyl5-Amino-2,3-dihydro-1H-indole-1-carboxylate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 034352
Product name: 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester
Packaging: 500mg
Price: $98
Updated: 2021/12/16

Matrix Scientific

Product number: 034352
Product name: 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester
Packaging: 1g
Price: $150
Updated: 2021/12/16

Matrix Scientific

Product number: 034352
Product name: 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester
Packaging: 5g
Price: $525
Updated: 2021/12/16

AK Scientific

Product number: 5492AA
Product name: tert-Butyl5-aminoindoline-1-carboxylate
Packaging: 5g
Price: $637
Updated: 2021/12/16

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1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Chemical Properties,Usage,Production

Synthesis

166104-19-4

129487-92-9

The general procedure for the synthesis of tert-butyl 5-aminoindoline-1-carboxylate from tert-butyl 5-nitro-1H-indole-1-carboxylate is as follows: XII; tert-butyl 5-amino-2,3-dihydro-indole-1-carboxylate; 6.8 g of tert-butyl 5-nitro-1H-indole-1-carboxylate was dissolved in 120 mL of methanol. To this solution was added 600 mg of 10% palladium carbon catalyst, followed by a hydrogenation reaction at room temperature for 1.5 hours. Upon completion of the reaction, the catalyst was removed by filtration and the solvent was evaporated under reduced pressure. The final product was 6 g of tert-butyl 5-aminoindoline-1-carboxylate in 100% yield of the theoretical value. The product was analyzed by mass spectrometry (ESI+) and showed m/z = 235 [M + H]+.

References

[1] Patent: WO2008/113760, 2008, A2. Location in patent: Page/Page column 92
[2] Patent: US2017/50964, 2017, A1. Location in patent: Paragraph 0734
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 23, p. 6481 - 6488
[4] Synthesis, 2007, # 10, p. 1509 - 1512

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Suppliers

China 77 India 1 United Kingdom 1 United States 9 Global 88

J & K SCIENTIFIC LTD.

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Bide Pharmatech Ltd.

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Hangzhou J&H Chemical Co., Ltd.

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View Lastest Price from 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE manufacturers

Career Henan Chemical Co

Product: 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE 129487-92-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1lg; 2kg; 5kg; 10kg; 100kg
Release date: 2019-08-31

129487-92-9, 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLERelated Search:

1-BOC-INDOLINE 4-(TERT-BUTOXYCARBONYLAMINO)ANILINE 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE (4-AMINO-2-METHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER [2-(3-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER tert-butyl 5-bromoindoline-1-carboxylate tert-butyl 5-bromofuran-2-carboxylate

tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate

1-Boc-5-aMinoindoline

2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate

5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester >=97%

6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester

1-Boc-2,3-dihydro-1H-indol-5-amine

5-AMINO-1-BOC-2,3-DIHYDROINDOLE

5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

tert-butyl 5-amino-2,3-dihydroindole-1-carboxylate

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE

tert-Butyl 5-aMinoindoline-1-carboxylate

1H-Indole-1-carboxylic acid, 5-aMino-2,3-dihydro-, 1,1-diMethylethyl ester

129487-92-9

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