ChemicalBook > CAS DataBase List > 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE

Product Name
1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
CAS No.
129487-92-9
Chemical Name
1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
Synonyms
1-Boc-5-aMinoindoline;5-AMINO-1-BOC-2,3-DIHYDROINDOLE;1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE;1-Boc-2,3-dihydro-1H-indol-5-amine;tert-Butyl 5-aMinoindoline-1-carboxylate;2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate;tert-butyl 5-amino-2,3-dihydroindole-1-carboxylate;tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate;5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester
CBNumber
CB8683580
Molecular Formula
C13H18N2O2
Formula Weight
234.29
MOL File
129487-92-9.mol
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1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Property

Boiling point:
385.2±41.0 °C(Predicted)
Density 
1.177±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
5.44±0.20(Predicted)
form 
liquid
color 
Brown
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Safety

HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T205238
Product name
tert-Butyl5-Amino-2,3-dihydro-1H-indole-1-carboxylate
Packaging
50mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
034352
Product name
5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester
Packaging
500mg
Price
$98
Updated
2021/12/16
Matrix Scientific
Product number
034352
Product name
5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester
Packaging
1g
Price
$150
Updated
2021/12/16
Matrix Scientific
Product number
034352
Product name
5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester
Packaging
5g
Price
$525
Updated
2021/12/16
AK Scientific
Product number
5492AA
Product name
tert-Butyl5-aminoindoline-1-carboxylate
Packaging
5g
Price
$637
Updated
2021/12/16
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1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Chemical Properties,Usage,Production

Synthesis

166104-19-4

129487-92-9

The general procedure for the synthesis of tert-butyl 5-aminoindoline-1-carboxylate from tert-butyl 5-nitro-1H-indole-1-carboxylate is as follows: XII; tert-butyl 5-amino-2,3-dihydro-indole-1-carboxylate; 6.8 g of tert-butyl 5-nitro-1H-indole-1-carboxylate was dissolved in 120 mL of methanol. To this solution was added 600 mg of 10% palladium carbon catalyst, followed by a hydrogenation reaction at room temperature for 1.5 hours. Upon completion of the reaction, the catalyst was removed by filtration and the solvent was evaporated under reduced pressure. The final product was 6 g of tert-butyl 5-aminoindoline-1-carboxylate in 100% yield of the theoretical value. The product was analyzed by mass spectrometry (ESI+) and showed m/z = 235 [M + H]+.

References

[1] Patent: WO2008/113760, 2008, A2. Location in patent: Page/Page column 92
[2] Patent: US2017/50964, 2017, A1. Location in patent: Paragraph 0734
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 23, p. 6481 - 6488
[4] Synthesis, 2007, # 10, p. 1509 - 1512

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Suppliers

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View Lastest Price from 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE manufacturers

Career Henan Chemical Co
Product
1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE 129487-92-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1lg; 2kg; 5kg; 10kg; 100kg
Release date
2019-08-31

129487-92-9, 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLERelated Search:

1-BOC-INDOLINE 4-(TERT-BUTOXYCARBONYLAMINO)ANILINE 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE (4-AMINO-2-METHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER [2-(3-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER tert-butyl 5-bromoindoline-1-carboxylate tert-butyl 5-bromofuran-2-carboxylate

  • tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate
  • 1-Boc-5-aMinoindoline
  • 2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate
  • 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester >=97%
  • 6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester
  • 1-Boc-2,3-dihydro-1H-indol-5-amine
  • 5-AMINO-1-BOC-2,3-DIHYDROINDOLE
  • 5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • tert-butyl 5-amino-2,3-dihydroindole-1-carboxylate
  • 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
  • tert-Butyl 5-aMinoindoline-1-carboxylate
  • 1H-Indole-1-carboxylic acid, 5-aMino-2,3-dihydro-, 1,1-diMethylethyl ester
  • 129487-92-9
  • pharmacetical