ChemicalBook > CAS DataBase List > H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH

H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH

Product Name
H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
CAS No.
107015-83-8
Chemical Name
H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
Synonyms
SP17;VHHQKLVFFAEDVGSNK;β-Amyloid (12-28);β-amyloid (12-28);BETA-AMYLOID (12-28);Bate-Amyloid (12-28);AMyloid b-Protein (12-28);Amyloid β-Protein (12-28);AMYLOID BETA-PROTEIN (12-28);M.W. 1955.20 C89H135N25O25
CBNumber
CB8686415
Molecular Formula
C89H135N25O25
Formula Weight
1955.18
MOL File
107015-83-8.mol
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H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Property

storage temp. 
−20°C
solubility 
≥195.5 mg/mL in DMSO; insoluble in EtOH; ≥59.8 mg/mL in H2O
form 
solid
Water Solubility 
Soluble to 0.70 mg/ml in water
Sequence
H-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
384477
Product name
Sp17
Packaging
96Tests
Price
$729
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364310
Product name
Beta-Amyloid (12-28)
Purity
> 95%
Packaging
10mg
Price
$1003
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0000716
Product name
BETA-AMYLOID (12-28)
Purity
95.00%
Packaging
5MG
Price
$1048.17
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110264
Product name
Amyloid beta-Protein (12-28)
Packaging
25mg
Price
$1515.25
Updated
2021/12/16
ApexBio Technology
Product number
A1123
Product name
AmyloidBeta-Peptide(12-28)(human)
Packaging
1mg
Price
$70
Updated
2021/12/16
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H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Chemical Properties,Usage,Production

Biological Activity

amyloid beta (aβ or abeta) is a peptide of 36–43 amino acids that is processed from the amyloid precursor protein. while best known as a component of amyloid plaques in association with alzheimer's disease, evidence has been found that aβ is a highly multifunctional peptide with significant non-pathological activity(1). aβ is the main component of deposits found in the brains of patients with alzheimer's disease. brain aβ is elevated in patients with sporadic alzheimer’s disease. aβ is the main constituent of brain parenchymal and vascular amyloid, it contributes to cerebrovascular lesions and is neurotoxic(2).figure1 formula of amyloid β-peptide (12-28) (human)figure2 signal pathway of amyloid β

References

1. Lahiri DK, Maloney B (September 2010). "Beyond the signaling effect role of amyloid–β42 on the processing of AβPP, and its clinical implications". Exp. Neurol. 225 (1): 51–4.2. Hardy J, Duff K, Hardy KG, Perez-Tur J, Hutton M (September 1998). "Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau". Nat. Neurosci. 1 (5): 355–8.

H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Suppliers

AdooQ BioScience, LLC
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+1 (866) 930-6790
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ApexBio Technology LLC
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American Peptide Company
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AnaSpec, Inc.
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Chem-Impex International, Inc.
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View Lastest Price from H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Bate-Amyloid (12-28) 107015-83-8
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
≥98.0%
Supply Ability
20 tons
Release date
2024-01-06
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Amyloid Bate-Protein (12-28)/Bate-Amyloid (12-28) 107015-83-8
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
>98%
Supply Ability
20 tons
Release date
2024-01-08
Career Henan Chemical Co
Product
H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH 107015-83-8
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

107015-83-8, H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OHRelated Search:


  • H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
  • BETA-AMYLOID (12-28)
  • BETA-AMYLOID PEPTIDE [12-28], HUMAN
  • ALZHEIMER'S DISEASE BETA-PROTEIN (12-28)
  • AMYLOID, BETA- (12-28), HUMAN
  • AMYLOID BETA-PROTEIN (12-28)
  • AMYLOID-BETA PROTEIN (12-28), HUMAN
  • AMYLOID BETA-PROTEIN FRAGMENT 12-28
  • AMYLOID BETA-PEPTIDE (12-28) (HUMAN)
  • SP17
  • VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS
  • VHHQKLVFFAEDVGSNK
  • M.W. 1955.20 C89H135N25O25
  • B-AMYLOID PROTEIN (12-28) >97% SYNTHETIC
  • AMYLOID B-PROTEIN FRAGMENT 12-28
  • Amyloidb-Peptide(12-28)(human)
  • amyloid β-protein fragment 12-28
  • Amyloid β-Peptide (12-28) (human)
  • AMyloid β-Protein (12-28) AlzheiMer's Disease β-Protein (12-28)
  • AlzheiMer's Disease b-Protein (12-28)
  • AMyloid b-Protein (12-28)
  • β-Amyloid (12-28)
  • L-Lysine, L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-
  • Amyloid β-Protein (12-28)/β-Amyloid (12-28)
  • β-Amyloid protein fragment(12-28)
  • H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH USP/EP/BP
  • Amyloid β-Protein (12-28)
  • AMyloid β-Protein (12-28) AlzheiMer's Disease β-Protein (12-28)
  • β-amyloid (12-28)
  • Bate-Amyloid (12-28)
  • Amyloid Bate-Protein (12-28)/Bate-Amyloid (12-28)
  • beta-Amyloid Peptide (12-28)(TFA salt)
  • 107015-83-8
  • C89H135N25O25
  • Neurodegenerative Disease Peptides
  • Peptides
  • Amino Acids and Peptides
  • Amyloid beta Protein Fragments
  • Biochemicals and Reagents
  • BioChemical
  • peptide
  • Amyloid beta Protein Fragments
  • Neurodegenerative Disease Peptides
  • Neuropeptides
  • Amyloid beta-peptide and related
  • Alzheimer