3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE

Product Name: 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE
CAS No.: 185259-85-2
Chemical Name: 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE
Synonyms: GR 46611;GR 46611, 5-HT1B/1D agonist;3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE;3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]prop-2-enamide;2-Propenamide, 3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]-
CBNumber: CB8690764
Molecular Formula: C23H27N3O2
Formula Weight: 377.48
MOL File: 185259-85-2.mol

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3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE Property

Boiling point:: 645.9±55.0 °C(Predicted)
Density: 1.168
storage temp.: 2-8°C
solubility: DMSO: 28 mg/mL, soluble
pka: 14.51±0.46(Predicted)
form: solid
color: white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Tocris

Product number: 0864
Product name: GR46611
Packaging: 10
Price: $130
Updated: 2021/12/16

Tocris

Product number: 0864
Product name: GR46611
Packaging: 50
Price: $544
Updated: 2021/12/16

TRC

Product number: G779553
Product name: GR46611
Packaging: 10mg
Price: $180
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008779
Product name: 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE
Purity: 95.00%
Packaging: 10MG
Price: $702.19
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008779
Product name: 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE
Purity: 95.00%
Packaging: 50MG
Price: $1199.42
Updated: 2021/12/16

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3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE Chemical Properties,Usage,Production

Uses

GR 46611is a 5-HT1D agonist.

Definition

ChEBI: 3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]-2-propenamide is a member of tryptamines.

Biological Activity

5-HT 1D receptor agonist. Blockade of GR 46611-induced hypothermia in the guinea pig provides a useful model with which to study the potency and duration of action of centrally acting 5-HT 1D receptor ligands.

3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE Suppliers

China 30 Germany 1 Switzerland 2 United Kingdom 3 United States 10 Global 46

3B Pharmachem (Wuhan) International Co.,Ltd.

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Jinan ponder chemical co. LTD

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185259-85-2, 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDERelated Search:

5-METHYL-N,N-DIMETHYLTRYPTAMINE 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE

3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE

GR 46611

3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]prop-2-enamide

2-Propenamide, 3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]-

GR 46611, 5-HT1B/1D agonist

185259-85-2