ChemicalBook > CAS DataBase List > REVERSIN 121

REVERSIN 121

Product Name
REVERSIN 121
CAS No.
174630-04-7
Chemical Name
REVERSIN 121
Synonyms
REVERSIN 121;BOC-ASP(OBZL)-LYS(Z)-OTBU;L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester
CBNumber
CB8699257
Molecular Formula
C34H47N3O9
Formula Weight
641.75
MOL File
Mol file
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REVERSIN 121 Property

Boiling point:
786.8±60.0 °C(Predicted)
Density 
1.163±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO or ethanol: soluble
form 
powder
pka
10.75±0.46(Predicted)
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R1276
Product name
Reversin 121
Purity
≥97% (HPLC), powder
Packaging
3mg
Price
$583
Updated
2024/03/01
Cayman Chemical
Product number
18603
Product name
Reversin 121
Purity
≥98%
Packaging
500μg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
18603
Product name
Reversin 121
Purity
≥98%
Packaging
1mg
Price
$59
Updated
2024/03/01
Cayman Chemical
Product number
18603
Product name
Reversin 121
Purity
≥98%
Packaging
5mg
Price
$198
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
PEP0004566
Product name
REVERSIN 121
Purity
95.00%
Packaging
3MG
Price
$874.34
Updated
2021/12/16
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REVERSIN 121 Chemical Properties,Usage,Production

Description

Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.

Uses

Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.

General Description

Reversin 121 is an analog of reversin and a dipeptide derivative.

Biochem/physiol Actions

Peptide chemosensitizer, inhibitor of P-glycoprotein.

REVERSIN 121 Preparation Products And Raw materials

Raw materials

Preparation Products

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REVERSIN 121 Suppliers

China 22 Switzerland 2 United Kingdom 3 United States 5 Global 32
Sigma-Aldrich
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021-61415566 800-8193336
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174630-04-7, REVERSIN 121Related Search:


  • REVERSIN 121
  • BOC-ASP(OBZL)-LYS(Z)-OTBU
  • L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester
  • 174630-04-7
  • C34H47N3O9
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Enzyme
  • P-Glycoprotein
  • P to Q
  • Biochemicals and Reagents
  • BioChemical