ChemicalBook > CAS DataBase List > REVERSIN 121
REVERSIN 121
- Product Name
- REVERSIN 121
- CAS No.
- 174630-04-7
- Chemical Name
- REVERSIN 121
- Synonyms
- REVERSIN 121;BOC-ASP(OBZL)-LYS(Z)-OTBU;L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester
- CBNumber
- CB8699257
- Molecular Formula
- C34H47N3O9
- Formula Weight
- 641.75
- MOL File
- Mol file
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REVERSIN 121 Property
- Boiling point:
- 786.8±60.0 °C(Predicted)
- Density
- 1.163±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO or ethanol: soluble
- form
- powder
- pka
- 10.75±0.46(Predicted)
- color
- white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- R1276
- Product name
- Reversin 121
- Purity
- ≥97% (HPLC), powder
- Packaging
- 3mg
- Price
- $583
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18603
- Product name
- Reversin 121
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $34
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18603
- Product name
- Reversin 121
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $59
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18603
- Product name
- Reversin 121
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $198
- Updated
- 2024/03/01
American Custom Chemicals Corporation
- Product number
- PEP0004566
- Product name
- REVERSIN 121
- Purity
- 95.00%
- Packaging
- 3MG
- Price
- $874.34
- Updated
- 2021/12/16
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REVERSIN 121 Chemical Properties,Usage,Production
Description
Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.
Uses
Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.
General Description
Reversin 121 is an analog of reversin and a dipeptide derivative.
Biochem/physiol Actions
Peptide chemosensitizer, inhibitor of P-glycoprotein.
REVERSIN 121 Preparation Products And Raw materials
Raw materials
Preparation Products
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REVERSIN 121 Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
- Tel
- --
- Fax
- --
- alexis-ch@alexis-corp.ch
- Country
- Switzerland
- ProdList
- 3599
- Advantage
- 74