ChemicalBook > CAS DataBase List > 3-Nitro-L-tyrosine

3-Nitro-L-tyrosine

Product Name
3-Nitro-L-tyrosine
CAS No.
621-44-3
Chemical Name
3-Nitro-L-tyrosine
Synonyms
3-NITRO-TYROSINE;NITROTYROSINE;H-TYR(3-NO2)-OH;Tyr(3'-NO2);Z-D-Dap(Boc);H-TYR(M-NO2)-OH;m-Nitro-L-Tyr-OH;H-3-NITRO-TYR-OH;H-M-NITRO-TYR-OH;M-NITRO-L-TYROSINE
CBNumber
CB8703176
Molecular Formula
C9H10N2O5
Formula Weight
226.19
MOL File
621-44-3.mol
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3-Nitro-L-tyrosine Property

Melting point:
233-235 °C (dec.) (lit.)
alpha 
4 º (c=1, 1N HCl)
Boiling point:
367.79°C (rough estimate)
Density 
1.4160 (rough estimate)
refractive index 
1.5373 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid (Slightly), Water
pka
2.17±0.20(Predicted)
form 
crystalline
color 
yellow to green
Water Solubility 
insoluble
BRN 
2813157
CAS DataBase Reference
621-44-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-37/39-26-36
WGK Germany 
3
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N7389
Product name
3-Nitro-L-tyrosine
Purity
crystalline
Packaging
5g
Price
$125
Updated
2024/03/01
Sigma-Aldrich
Product number
N7389
Product name
3-Nitro-L-tyrosine
Purity
crystalline
Packaging
10g
Price
$236
Updated
2024/03/01
TCI Chemical
Product number
N0905
Product name
3-Nitro-L-tyrosine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$183
Updated
2024/03/01
TCI Chemical
Product number
N0905
Product name
3-Nitro-L-tyrosine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$656
Updated
2024/03/01
Alfa Aesar
Product number
A11018
Product name
3-Nitro-L-tyrosine, 98%
Packaging
5g
Price
$44.8
Updated
2023/06/20
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3-Nitro-L-tyrosine Chemical Properties,Usage,Production

Description

Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo. Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions. The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry.

Chemical Properties

ochre-yellow to yellow-green powder

Uses

A marker for peroxynitrite. Oxidant and cytotoxic agent.

Uses

3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage.

Definition

ChEBI: 3-nitro-L-tyrosine is a 3-nitrotyrosine comprising L-tyrosine having a nitro group at the 3-position on the phenyl ring. It is a L-tyrosine derivative, a non-proteinogenic L-alpha-amino acid and a 3-nitrotyrosine. It is an enantiomer of a 3-nitro-D-tyrosine.

Biochem/physiol Actions

Oxidant and cytotoxic agent.

3-Nitro-L-tyrosine Preparation Products And Raw materials

Raw materials

Preparation Products

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621-44-3, 3-Nitro-L-tyrosineRelated Search:

H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH L-Tyrosine Boc-D-Tyr-OH 3-NITRO-L-TYROSINE ETHYL ESTER HYDROCHLORIDE 3,5-DINITRO-L-TYROSINE MONOHYDRATE N-Acetyl-3,5-dinitro-L-tyrosine NITROGEN DIOXIDE FMOC-3-NITRO-L-TYROSINE,N-ALPHA-FMOC-3-NITRO-L-TYROSINE,NALPHA-9-Fluorenylmethoxycarbonyl-3-nitro-L-tyrosine 3,5-DINITRO-L-TYROSINE MONOHYDRATE, 97 3-NITRO-D-TYROSINE FMOC-3,5-DINITRO-TYR-OH BOC-TYR(BZL, 3-NO2)-OH N-ACETYL-L-3-NITROTYROSINE ETHYL ESTER (S)-2-AMINO-3-(4-HYDROXY-3-NITRO-PHENYL)-PROPIONIC ACID METHYL ESTER 3,5-DINITRO-L-TYROSINE SODIUM SALT AC-3,5-DINITRO-TYR-OET BOC-3-NITRO-L-TYROSINE ABZ-SER-PRO-3-NITRO-TYR-OH

  • (2R)-2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid
  • L-Tyrosine, 3-nitro-
  • 3-Nitro-L-tyrosine,99%
  • (S)-2-aMino-3-(4-hydroxy-3-nitrophenyl)propanoic acid
  • Z-D-Dap(Boc)
  • 3-NITRO-L-TYROSINE (RING-13C6)
  • (S)-3-(3-Nitro-4-hydroxyphenyl)alanine
  • 3-Nitro-L-tyrosine≥ 98% (Assay)
  • m-Nitro-L-Tyr-OH
  • M-NITRO-L-TYROSINE
  • NITROTYROSINE
  • 3-NITRO-4-HYDROXY-PHENYLALANINE
  • 3-NITRO-TYROSINE
  • 3-NITRO-L-TYROSINE
  • Tyr(3'-NO2)
  • 3-NITRO-TYROSINEH-TYR(3-NO2)-OH
  • 3-Nitro-L-tyrosine 99%
  • H-TYR(M-NO2)-OH
  • H-TYR(3-NO2)-OH
  • H-4-HYDROXY-3-NITRO-PHE-OH
  • H-3-NITRO-L-TYROSINE
  • H-3-NITRO-TYR-OH
  • H-M-NITRO-TYR-OH
  • (2S)-2-ammonio-3-(3-nitro-4-oxidophenyl)propanoate
  • 3-Nitro-L-tyrosine&gt
  • 3-Nitro-L-tyrosine USP/EP/BP
  • 3-Nitro-L-tyrosine, ≥ 98.0%
  • Rabbit Anti-3-Nitrotyrosine antibody
  • 621-44-3
  • O2NC6H34OHCH2CHNH2CO2H
  • C9H9N2O5
  • Unnatural Amino Acid Derivatives
  • Tyrosine Derivatives
  • Specialty Synthesis
  • Peptide Synthesis
  • Pharmaceutical Raw Materials
  • Amino Acids
  • Tyrosine [Tyr, Y]
  • Unusual Amino Acids
  • Oxidative Stress Proteins and ReagentsPeptide Synthesis
  • Cell Stress
  • Nitric Oxide and Cell Stress
  • Amino Acids & Derivatives
  • Aromatics
  • Peptide Synthesis
  • Tyrosine Derivatives
  • Unnatural Amino Acid Derivatives