3-Nitro-L-tyrosine

Product Name: 3-Nitro-L-tyrosine
CAS No.: 621-44-3
Chemical Name: 3-Nitro-L-tyrosine
Synonyms: 3-NITRO-TYROSINE;NITROTYROSINE;H-TYR(3-NO2)-OH;Tyr(3'-NO2);Z-D-Dap(Boc);H-TYR(M-NO2)-OH;m-Nitro-L-Tyr-OH;H-3-NITRO-TYR-OH;H-M-NITRO-TYR-OH;M-NITRO-L-TYROSINE
CBNumber: CB8703176
Molecular Formula: C9H10N2O5
Formula Weight: 226.19
MOL File: 621-44-3.mol

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3-Nitro-L-tyrosine Property

Melting point:: 233-235 °C (dec.) (lit.)
alpha: 4 º (c=1, 1N HCl)
Boiling point:: 367.79°C (rough estimate)
Density: 1.4160 (rough estimate)
refractive index: 1.5373 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Aqueous Acid (Slightly), Water
pka: 2.17±0.20(Predicted)
form: crystalline
color: yellow to green
Water Solubility: insoluble
BRN: 2813157
CAS DataBase Reference: 621-44-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 24/25-37/39-26-36
WGK Germany: 3
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N7389
Product name: 3-Nitro-L-tyrosine
Purity: crystalline
Packaging: 5g
Price: $125
Updated: 2024/03/01

Sigma-Aldrich

Product number: N7389
Product name: 3-Nitro-L-tyrosine
Purity: crystalline
Packaging: 10g
Price: $236
Updated: 2024/03/01

TCI Chemical

Product number: N0905
Product name: 3-Nitro-L-tyrosine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $183
Updated: 2024/03/01

TCI Chemical

Product number: N0905
Product name: 3-Nitro-L-tyrosine
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $656
Updated: 2024/03/01

Alfa Aesar

Product number: A11018
Product name: 3-Nitro-L-tyrosine, 98%
Packaging: 5g
Price: $44.8
Updated: 2023/06/20

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3-Nitro-L-tyrosine Chemical Properties,Usage,Production

Description

Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo. Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions. The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry.

Chemical Properties

ochre-yellow to yellow-green powder

Uses

A marker for peroxynitrite. Oxidant and cytotoxic agent.

Uses

3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage.

Definition

ChEBI: 3-nitro-L-tyrosine is a 3-nitrotyrosine comprising L-tyrosine having a nitro group at the 3-position on the phenyl ring. It is a L-tyrosine derivative, a non-proteinogenic L-alpha-amino acid and a 3-nitrotyrosine. It is an enantiomer of a 3-nitro-D-tyrosine.

Biochem/physiol Actions

Oxidant and cytotoxic agent.

3-Nitro-L-tyrosine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Nitro-L-tyrosine Suppliers

Americas 1 Canada 1 China 139 Czech Republic 1 Europe 3 France 1 Germany 4 India 5 Japan 4 Switzerland 10 United Kingdom 11 United States 42 Global 222

BIOSYNTH AG

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Senn Chemicals AG

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Biosynth AG

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Alexis Corporation

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621-44-3, 3-Nitro-L-tyrosineRelated Search:

H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH L-Tyrosine Boc-D-Tyr-OH 3-NITRO-L-TYROSINE ETHYL ESTER HYDROCHLORIDE 3,5-DINITRO-L-TYROSINE MONOHYDRATE N-Acetyl-3,5-dinitro-L-tyrosine NITROGEN DIOXIDE FMOC-3-NITRO-L-TYROSINE,N-ALPHA-FMOC-3-NITRO-L-TYROSINE,NALPHA-9-Fluorenylmethoxycarbonyl-3-nitro-L-tyrosine 3,5-DINITRO-L-TYROSINE MONOHYDRATE, 97 3-NITRO-D-TYROSINE FMOC-3,5-DINITRO-TYR-OH BOC-TYR(BZL, 3-NO2)-OH N-ACETYL-L-3-NITROTYROSINE ETHYL ESTER (S)-2-AMINO-3-(4-HYDROXY-3-NITRO-PHENYL)-PROPIONIC ACID METHYL ESTER 3,5-DINITRO-L-TYROSINE SODIUM SALT AC-3,5-DINITRO-TYR-OET BOC-3-NITRO-L-TYROSINE ABZ-SER-PRO-3-NITRO-TYR-OH

(2R)-2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid

L-Tyrosine, 3-nitro-

3-Nitro-L-tyrosine,99%

(S)-2-aMino-3-(4-hydroxy-3-nitrophenyl)propanoic acid

Z-D-Dap(Boc)

3-NITRO-L-TYROSINE (RING-13C6)

(S)-3-(3-Nitro-4-hydroxyphenyl)alanine

3-Nitro-L-tyrosine≥ 98% (Assay)

m-Nitro-L-Tyr-OH

M-NITRO-L-TYROSINE

NITROTYROSINE

3-NITRO-4-HYDROXY-PHENYLALANINE

3-NITRO-TYROSINE

3-NITRO-L-TYROSINE

Tyr(3'-NO2)

3-NITRO-TYROSINEH-TYR(3-NO2)-OH

3-Nitro-L-tyrosine 99%

H-TYR(M-NO2)-OH

H-TYR(3-NO2)-OH

H-4-HYDROXY-3-NITRO-PHE-OH

H-3-NITRO-L-TYROSINE

H-3-NITRO-TYR-OH

H-M-NITRO-TYR-OH

(2S)-2-ammonio-3-(3-nitro-4-oxidophenyl)propanoate

3-Nitro-L-tyrosine&gt

3-Nitro-L-tyrosine USP/EP/BP

3-Nitro-L-tyrosine, ≥ 98.0%

Rabbit Anti-3-Nitrotyrosine antibody

621-44-3

O2NC6H34OHCH2CHNH2CO2H

C9H9N2O5

Unnatural Amino Acid Derivatives

Tyrosine Derivatives

Specialty Synthesis

Peptide Synthesis

Pharmaceutical Raw Materials

Amino Acids

Tyrosine [Tyr, Y]

Unusual Amino Acids

Oxidative Stress Proteins and ReagentsPeptide Synthesis

Cell Stress

Nitric Oxide and Cell Stress

Amino Acids & Derivatives

Aromatics

Peptide Synthesis

Tyrosine Derivatives

Unnatural Amino Acid Derivatives