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OLDA

Product Name
OLDA
CAS No.
105955-11-1
Chemical Name
OLDA
Synonyms
ODA;OLDA;N-OLEOYLDOPAMINE;N-Oleoyldopamine (OLDA);N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]9Z-OCTADECENAMIDE;(Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]octadec-9-enamide;(9Z)-N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]-9-OCTADECENAMIDE;9-Octadecenamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-, (9Z)-
CBNumber
CB8708878
Molecular Formula
C26H43NO3
Formula Weight
417.62
MOL File
105955-11-1.mol
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OLDA Property

Melting point:
60-61oC
Boiling point:
619.5±55.0 °C(Predicted)
Density 
1.004±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: ~20 mg/mL, soluble
form 
powder
pka
9.79±0.10(Predicted)
color 
white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10115
Product name
N-Oleoyl Dopamine
Purity
≥98%
Packaging
5mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
10115
Product name
N-Oleoyl Dopamine
Purity
≥98%
Packaging
10mg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
10115
Product name
N-Oleoyl Dopamine
Purity
≥98%
Packaging
50mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
10115
Product name
N-Oleoyl Dopamine
Purity
≥98%
Packaging
100mg
Price
$595
Updated
2024/03/01
Tocris
Product number
1641
Product name
OLDA
Purity
≥99%(HPLC)
Packaging
5
Price
$123
Updated
2021/12/16
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OLDA Chemical Properties,Usage,Production

Uses

N-Oleoyldopamine is a bioactive lipid found in the mammalian brain that selectively activates the transient receptor potential vanilloid type 1 (TRPV1) channel. It is also a 5-lipoxygenase inhibitor.

Definition

ChEBI: N-oleoyldopamine is a fatty amide resulting from the formal condensation of the carboxy group of oleic acid with the amino group of dopamine. Synthesised in catecholaminergic neurons, it crosses the blood-brain barrier and might be considered as a carrier of dopamine into the brain. It is a transient receptor potential vanilloid type 1 (TRPV1) receptor agonist. It has a role as a TRPV1 agonist. It is a fatty amide, a secondary carboxamide, a member of catechols and a N-(fatty acyl)-dopamine. It is functionally related to a dopamine and an oleic acid.

Biological Activity

Potent endogenous vanilloid TRPV1 (VR1) receptor agonist (EC 50 = 36 nM at hVR1) with low affinity for rCB 1 receptors (K i = 1.6 μ M). Potently induces VR1-mediated thermal hyperalgesia in rats in vivo .

storage

Desiccate at -20°C

OLDA Preparation Products And Raw materials

Raw materials

Preparation Products

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OLDA Suppliers

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105955-11-1, OLDARelated Search:


  • (9Z)-N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]-9-OCTADECENAMIDE
  • N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]9Z-OCTADECENAMIDE
  • OLDA
  • ODA
  • N-OLEOYLDOPAMINE
  • N-Oleoyldopamine (OLDA)
  • (Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]octadec-9-enamide
  • 9-Octadecenamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-, (9Z)-
  • 105955-11-1
  • C26H43NO3
  • Vanilloid/TRPV channel