2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE
- Product Name
- 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE
- CAS No.
- 13162-27-1
- Chemical Name
- 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE
- Synonyms
- 2,4-dichloro-6-methylpyrimidin-5-amine;4-Dichloro-5-aMino-6-MethylpyriMidine;2,4-Dichloro-6-methyl-5-pyrimidinamine;5-Pyrimidinamine,2,4-dichloro-6-methyl-;5-Amino-6-methyl-2,4-dichloropyrimidine;2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE;2,4-DICHLORO-6-METHYL-PYRIMIDIN-5-YLAMINE;Pyrimidine, 5-amino-2,4-dichloro-6-methyl-;2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE ISO 9001:2015 REACH;2,4-Dichloro-6-methylpyrimidin-5-amine, 5-Amino-2,4-dichloro-6-methyl-1,3-diazine
- CBNumber
- CB8711377
- Molecular Formula
- C5H5Cl2N3
- Formula Weight
- 178.02
- MOL File
- 13162-27-1.mol
2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE Property
- Melting point:
- 115-116.5℃
- Boiling point:
- 281.6±35.0 °C(Predicted)
- Density
- 1.504±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- -0.83±0.39(Predicted)
- Appearance
- Light brown to brown Solid
- InChI
- InChI=1S/C5H5Cl2N3/c1-2-3(8)4(6)10-5(7)9-2/h8H2,1H3
- InChIKey
- FDMMHWIFYCXEOF-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC(C)=C(N)C(Cl)=N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D437243
- Product name
- 2,4-Dichloro-6-methylpyrimidin-5-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D437243
- Product name
- 2,4-Dichloro-6-methylpyrimidin-5-amine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 3H30-5-W5
- Product name
- 5-Amino-2,4-dichloro-6-methylpyrimidine
- Purity
- 97%
- Packaging
- 5G
- Price
- $64
- Updated
- 2021/12/16
- Product number
- OR14760
- Product name
- 5-Amino-2,4-dichloro-6-methylpyrimidine
- Packaging
- 10g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- D11604
- Product name
- 2,4-Dichloro-5-amino-6-methylpyrimidine
- Packaging
- 25g
- Price
- $87
- Updated
- 2021/12/16
2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE Chemical Properties,Usage,Production
Uses
2,4-dichloro-6-methylpyrimidin-5-amine is an amine compound that can be used as a pharmaceutical intermediate or raw material for organic synthesis.
Synthesis
13162-26-0
13162-27-1
2,4-Dichloro-5-nitro-6-methylpyrimidine (860 mg) was used as a feedstock and co-dissolved with Pd/C (180 mg) in ethyl acetate (30 mL). Hydrogen was passed three times at room temperature to displace the air in the reaction system, followed by the reaction at 40 psi hydrogen pressure. Upon completion of the reaction, the Pd/C catalyst was removed by filtration to afford the yellow solid product 2,4-dichloro-5-amino-6-methylpyrimidine (500 mg) in 65.1% yield.
References
[1] Heterocyclic Communications, 2014, vol. 20, # 5, p. 275 - 279
[2] Patent: CN105906621, 2016, A. Location in patent: Paragraph 0032
[3] Journal of Heterocyclic Chemistry, 2016, vol. 53, # 3, p. 832 - 839
[4] Journal of the American Chemical Society, 1954, vol. 76, p. 1953
[5] Yakugaku Zasshi, 1942, vol. 62, p. 315,333; dtsch. Ref. S. 95, 106
2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE manufacturers
- Product
- 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE 13162-27-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-07
- Product
- 5-Pyrimidinamine,2,4-dichloro-6-methyl- 13162-27-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-09