ChemicalBook > CAS DataBase List > 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE

2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE

Product Name
2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE
CAS No.
13162-27-1
Chemical Name
2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE
Synonyms
2,4-dichloro-6-methylpyrimidin-5-amine;4-Dichloro-5-aMino-6-MethylpyriMidine;2,4-Dichloro-6-methyl-5-pyrimidinamine;5-Pyrimidinamine,2,4-dichloro-6-methyl-;5-Amino-6-methyl-2,4-dichloropyrimidine;2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE;2,4-DICHLORO-6-METHYL-PYRIMIDIN-5-YLAMINE;Pyrimidine, 5-amino-2,4-dichloro-6-methyl-;2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE ISO 9001:2015 REACH;2,4-Dichloro-6-methylpyrimidin-5-amine, 5-Amino-2,4-dichloro-6-methyl-1,3-diazine
CBNumber
CB8711377
Molecular Formula
C5H5Cl2N3
Formula Weight
178.02
MOL File
13162-27-1.mol
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2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE Property

Melting point:
115-116.5℃
Boiling point:
281.6±35.0 °C(Predicted)
Density 
1.504±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
-0.83±0.39(Predicted)
Appearance
Light brown to brown Solid
InChI
InChI=1S/C5H5Cl2N3/c1-2-3(8)4(6)10-5(7)9-2/h8H2,1H3
InChIKey
FDMMHWIFYCXEOF-UHFFFAOYSA-N
SMILES
C1(Cl)=NC(C)=C(N)C(Cl)=N1
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-41
Safety Statements 
26-39
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D437243
Product name
2,4-Dichloro-6-methylpyrimidin-5-amine
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
D437243
Product name
2,4-Dichloro-6-methylpyrimidin-5-amine
Packaging
100mg
Price
$60
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-5-W5
Product name
5-Amino-2,4-dichloro-6-methylpyrimidine
Purity
97%
Packaging
5G
Price
$64
Updated
2021/12/16
Apolloscientific
Product number
OR14760
Product name
5-Amino-2,4-dichloro-6-methylpyrimidine
Packaging
10g
Price
$87
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
D11604
Product name
2,4-Dichloro-5-amino-6-methylpyrimidine
Packaging
25g
Price
$87
Updated
2021/12/16
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2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE Chemical Properties,Usage,Production

Uses

2,4-dichloro-6-methylpyrimidin-5-amine is an amine compound that can be used as a pharmaceutical intermediate or raw material for organic synthesis.

Synthesis

13162-26-0

13162-27-1

2,4-Dichloro-5-nitro-6-methylpyrimidine (860 mg) was used as a feedstock and co-dissolved with Pd/C (180 mg) in ethyl acetate (30 mL). Hydrogen was passed three times at room temperature to displace the air in the reaction system, followed by the reaction at 40 psi hydrogen pressure. Upon completion of the reaction, the Pd/C catalyst was removed by filtration to afford the yellow solid product 2,4-dichloro-5-amino-6-methylpyrimidine (500 mg) in 65.1% yield.

References

[1] Heterocyclic Communications, 2014, vol. 20, # 5, p. 275 - 279
[2] Patent: CN105906621, 2016, A. Location in patent: Paragraph 0032
[3] Journal of Heterocyclic Chemistry, 2016, vol. 53, # 3, p. 832 - 839
[4] Journal of the American Chemical Society, 1954, vol. 76, p. 1953
[5] Yakugaku Zasshi, 1942, vol. 62, p. 315,333; dtsch. Ref. S. 95, 106

2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE Suppliers

Shandong Zhonghan Pharmaceutical Co.,Ltd.
Tel
19862069201
Email
3844950497@qq.com
Country
China
ProdList
289
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Nan Jing Dirise Chemcial Co.,LTD
Tel
025-52161033 15312098939
Fax
025-83254025
Email
sales@njdrschem.com
Country
China
ProdList
583
Advantage
64
Shanghai yirong biology science and technology co., ltd
Tel
18049974220
Fax
+86 (21) 51062076
Email
3060526242@qq.com
Country
China
ProdList
995
Advantage
60
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
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View Lastest Price from 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE manufacturers

Dideu Industries Group Limited
Product
2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE 13162-27-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-07
Career Henan Chemical Co
Product
5-Pyrimidinamine,2,4-dichloro-6-methyl- 13162-27-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-09

13162-27-1, 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINERelated Search:


  • 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE
  • 2,4-DICHLORO-6-METHYL-PYRIMIDIN-5-YLAMINE
  • 2,4-dichloro-6-methylpyrimidin-5-amine
  • 4-Dichloro-5-aMino-6-MethylpyriMidine
  • 2,4-Dichloro-6-methylpyrimidin-5-amine, 5-Amino-2,4-dichloro-6-methyl-1,3-diazine
  • 5-Pyrimidinamine,2,4-dichloro-6-methyl-
  • Pyrimidine, 5-amino-2,4-dichloro-6-methyl-
  • 5-Amino-6-methyl-2,4-dichloropyrimidine
  • 2,4-Dichloro-6-methyl-5-pyrimidinamine
  • 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE ISO 9001:2015 REACH
  • 13162-27-1
  • Building Blocks
  • Pyrimidine