2,4-Dichloro-6-methyl-5-nitropyrimidine

Product Name: 2,4-Dichloro-6-methyl-5-nitropyrimidine
CAS No.: 13162-26-0
Chemical Name: 2,4-Dichloro-6-methyl-5-nitropyrimidine
Synonyms: 2,4-Dic;NSC 122005;2,4-Dichloro-6-Methyl-5-Nitro;Methyl 2,6-Dichloro-5-nitropyriMidine;2,4-dichlor-6-methyl-5-nitropyrimidin;4-Dichloro-6-Methyl-5-nitro-pyriMidine;2,4-dichloro-6-methyl-5-nitropyrimidin;2,6-DICHLORO-4-METHYL-5-NITROPYRIMIDINE;2,4-DICHLORO-5-NITRO-6-METHYLPYRIMIDINE;2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE
CBNumber: CB6320858
Molecular Formula: C5H3Cl2N3O2
Formula Weight: 208
MOL File: 13162-26-0.mol

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2,4-Dichloro-6-methyl-5-nitropyrimidine Property

Melting point:: 52-54°C
Boiling point:: 135-136 °C(Press: 22 Torr)
Density: 1.626±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: -5.30±0.39(Predicted)
form: Solid
color: Pale Yellow to Light Beige
Stability:: Moisture Sensitive
InChI: InChI=1S/C5H3Cl2N3O2/c1-2-3(10(11)12)4(6)9-5(7)8-2/h1H3
InChIKey: NBCOZXBHPKSFSA-UHFFFAOYSA-N
SMILES: C1(Cl)=NC(C)=C([N+]([O-])=O)C(Cl)=N1
CAS DataBase Reference: 13162-26-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-41-36/37/38
Safety Statements: 26-39-36/37/39
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D435450
Product name: 2,4-Dichloro-6-methyl-5-nitropyrimidine
Packaging: 25g
Price: $150
Updated: 2021/12/16

Usbiological

Product number: D3531-25
Product name: 2,4-Dichloro-6-methyl-5-nitropyrimidine
Packaging: 5g
Price: $333
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ND70435
Product name: 2,4-Dichloro-5-nitro-6-methylpyrimidine
Packaging: 250g
Price: $340
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0017657
Product name: 2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE
Purity: 95.00%
Packaging: 1G
Price: $410
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0017657
Product name: 2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE
Purity: 95.00%
Packaging: 2.5G
Price: $425
Updated: 2021/12/16

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2,4-Dichloro-6-methyl-5-nitropyrimidine Chemical Properties,Usage,Production

Chemical Properties

Yellow Crystalline Solid

Uses

A synthetic intermediate

Synthesis

16632-21-6

13162-26-0

General procedure for the synthesis of 2,4-dichloro-5-nitro-6-methylpyrimidine from 2,4-dihydroxy-6-methyl-5-nitropyrimidine: 2,4-dihydroxy-6-methyl-5-nitropyrimidine (1 eq.) was dissolved in 17.54 mL of phosphoryl chloride, and 2.92 mL of N,N-dimethylaniline (1 eq.) was slowly added dropwise at room temperature. Subsequently, 8.04 μL of DMF (0.00445 eq.) was slowly added under reflux conditions and the reaction lasted for 8 hours. Upon completion of the reaction, the trichlorophosphorus oxide was removed by distillation under reduced pressure. Ice water was added to the residue and extracted with ethyl acetate. The organic layers were combined, washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by rotary evaporation to give a light yellow to brown oil. The oily substance was purified by column chromatographic separation to give a final yellow solid 2,4-dichloro-5-nitro-6-methylpyrimidine (1 g) in 65% yield.

References

[1] Patent: CN105906621, 2016, A. Location in patent: Paragraph 0031
[2] Bulletin de la Societe Chimique de France, 1951, p. 428
[3] Helvetica Chimica Acta, 1951, vol. 34, p. 835,837
[4] Journal of the Chemical Society, 1951, p. 1004,1015
[5] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, vol. 24, p. 84

2,4-Dichloro-6-methyl-5-nitropyrimidine Preparation Products And Raw materials

Raw materials

6-Methyluracil Phosphorus oxitrichloride Diethyl ether Sodium bicarbonate Nitric acid N,N-Diethylaniline Phosphorus pentoxide

Preparation Products

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2,4-Dichloro-6-methyl-5-nitropyrimidine Suppliers

Canada 2 China 196 Europe 2 Germany 2 India 5 Slovakia 1 Switzerland 1 United Kingdom 12 United States 34 Global 255

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View Lastest Price from 2,4-Dichloro-6-methyl-5-nitropyrimidine manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 2,4-Dichloro-6-methyl-5-nitropyrimidine 13162-26-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-10-28

Dideu Industries Group Limited

Product: 2,4-Dichloro-6-methyl-5-nitropyrimidine 13162-26-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-06

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2,4-Dichloro-6-methyl-5-nitropyrimidine 13162-26-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

13162-26-0, 2,4-Dichloro-6-methyl-5-nitropyrimidineRelated Search:

4,6-Dichloro-5-nitropyrimidine Methyl acetate Dichlorodimethylsilane 2,4-Dichloro-5-methylpyrimidine 2,4-Dichloro-5-nitropyrimidine 2-Chloro-5-chloromethylpyridine METSULFURON METHYL Methyl salicylate Dichloromethylphenylsilane 1,3-Dichloro-5,5-dimethylhydantoin 2,4-Dichloropyrimidine 1,1-Dichlorodimethyl ether Tribenuron methyl Dichloroacetic acid Pirimiphos-methyl Kresoxim-methyl Thiophanate-methyl Methyl

2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE

2,4-DICHLORO-5-NITRO-6-METHYLPYRIMIDINE

2,6-DICHLORO-4-METHYL-5-NITROPYRIMIDINE

2,4-Dichloro-6-Methyl-5-Nitro

Pyrimidine, 2,4-dichloro-6-methyl-5-nitro-

2,4-Dichloro-6-methyl-5-nitropyrimidine ,98%

2,4-dichloro-6-methyl-5-nitropyrimidin

4-Dichloro-6-Methyl-5-nitro-pyriMidine

Methyl 2,6-Dichloro-5-nitropyriMidine

NSC 122005

2,4-Dic

2,4-Dichloro-6-methyl-5-nitropyrimidine ISO 9001：2015 REACH

2,4-dichlor-6-methyl-5-nitropyrimidin

13162-26-0

13126-26-0

162-26-0

C5H4Cl2N3O2

C5H3Cl2N3O2

C5H3C12N3O2

Heterocycle-Pyrimidine series

Bases & Related Reagents

Nucleotides

Pyrimidine Series

Nucleotides and Nucleosides

Pyrimidines

APIs & Intermediate

Pyrimidine

Pyridines, Pyrimidines, Purines and Pteredines