Methyl 2-bromo-5-nitrobenzoate
- Product Name
- Methyl 2-bromo-5-nitrobenzoate
- CAS No.
- 6942-36-5
- Chemical Name
- Methyl 2-bromo-5-nitrobenzoate
- Synonyms
- METHYL 2-BROMO-5-NITROBENZOATE;METHYL 2-BROMO-5-NITROBENZOIC ACID;Methyl 2-Bromo-5-nitrobenzoate >Methyl 2-bromo-5-nitrobenzoate 97%;Methyl 2-bromo-5-nitrobenzoate, 98+%;2-BROMO-5-NITROBENZOIC ACID METHYL ESTER;Benzoic acid, 2-bromo-5-nitro-, methyl ester;Methyl 2-bromo-5-nitrobenzoate ISO 9001：2015 REACH
- CBNumber
- CB8722100
- Molecular Formula
- C8H6BrNO4
- Formula Weight
- 260.04
- MOL File
- 6942-36-5.mol
Methyl 2-bromo-5-nitrobenzoate Property
- Melting point:
- 79-81 °C (lit.)
- Boiling point:
- 326.7±22.0 °C(Predicted)
- Density
- 1.673±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform, DCM. Ethyl Acetate
- form
- Crystalline Powder
- color
- Yellow
- BRN
- 2617575
- CAS DataBase Reference
- 6942-36-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 300217
- Product name
- Methyl 2-bromo-5-nitrobenzoate
- Purity
- 99%
- Packaging
- 1g
- Price
- $55.7
- Updated
- 2023/01/07
- Product number
- B1916
- Product name
- Methyl 2-Bromo-5-nitrobenzoate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $37
- Updated
- 2025/07/31
- Product number
- B1916
- Product name
- Methyl 2-Bromo-5-nitrobenzoate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $106
- Updated
- 2025/07/31
- Product number
- B687295
- Product name
- 2-Bromo-5-nitrobenzoicAcidMethylEster
- Packaging
- 50mg
- Price
- $1550
- Updated
- 2021/12/16
- Product number
- 44070
- Product name
- 2-Bromo-5-nitrobenzoicAcidMethylEster
- Packaging
- 50mg
- Price
- $2475
- Updated
- 2021/12/16
Methyl 2-bromo-5-nitrobenzoate Chemical Properties,Usage,Production
Chemical Properties
yellow crystalline powder
Uses
Methyl 2-bromo-5-nitrobenzoate may be used in chemical synthesis.
Synthesis
67-56-1
943-14-6
6942-36-5
Methyl 2-bromo-5-nitrobenzoate was synthesized by esterification reaction using methanol and 2-bromo-5-nitrobenzoic acid as raw materials. The specific steps are as follows: in a dry reaction flask, 2-bromo-5-nitrobenzoic acid was dissolved in an appropriate amount of methanol, and a catalytic amount of concentrated sulfuric acid was added. The reaction mixture was stirred under reflux conditions for 6 hours. Upon completion of the reaction, the mixture was cooled to room temperature, poured into ice water and neutralized with sodium bicarbonate solution to pH=7. Subsequently, the product was extracted with dichloromethane, the organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=10:1) to afford methyl 2-bromo-5-nitrobenzoate in white crystalline form in 81% yield. The structure of the product was confirmed by 1H NMR and 13C NMR: 1H NMR (400 MHz, CDCl3) δ 4.00 (s, 3H), 7.88 (d, J = 8.76 Hz, 1H), 8.18 (dd, J = 2.76 Hz, 1H), 8.66 (d, J = 2.74 Hz, 1H); 13C NMR (100 MHz, CDCl3) δ 53.12, 126.33, 126.61, 129.24, 133.12, 135.71, 146.70, 164.48.
References
[1] Journal of the American Chemical Society,
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 54 - 55
[3] Synthesis, 1999, # 7, p. 1246 - 1250
[4] Patent: US2009/131527, 2009, A1. Location in patent: Page/Page column 8
[5] Tetrahedron Letters, 2012, vol. 53, # 46, p. 6245 - 6249,5
Methyl 2-bromo-5-nitrobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 2-bromo-5-nitrobenzoate manufacturers
- Product
- Methyl 2-bromo-5-nitrobenzoate 6942-36-5
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
- Product
- Methyl 2-bromo-5-nitrobenzoate 6942-36-5
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100 tons
- Release date
- 2020-01-10
- Product
- Methyl 2-bromo-5-nitrobenzoate 6942-36-5
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-07-09