ChemicalBook > CAS DataBase List > Mangiferin

Mangiferin

Product Name
Mangiferin
CAS No.
4773-96-0
Chemical Name
Mangiferin
Synonyms
chinonin;Mangiferin Standard;2-beta-d-glucopyranosyl-1,3,6,7-tetrahydroxy-9h-xanthen-9-on;aphloiol;chinomin;ChinoMine;MANGIFERN;alpizarin;hedysarid;Mangiferin
CBNumber
CB8723435
Molecular Formula
C19H18O11
Formula Weight
422.34
MOL File
4773-96-0.mol
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Mangiferin Property

Melting point:
269-270°C
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly), Pyridine (Slightly, Heated)
form 
Solid
Boiling point:
842.7±65.0 °C(Predicted)
Density 
1.843±0.06 g/cm3(Predicted)
pka
6.09±0.20(Predicted)
color 
Pale Yellow
Stability:
Hygroscopic
InChI
InChI=1/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/s3
InChIKey
AEDDIBAIWPIIBD-AZBPZEDSNA-N
SMILES
OC1=C([C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C(O)=CC2OC3=CC(O)=C(O)C=C3C(=O)C1=2 |&1:3,4,5,7,9,r|
LogP
0.130 (est)
CAS DataBase Reference
4773-96-0(CAS DataBase Reference)
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Safety

Hazard Codes 
T+,Xi,Xn
Risk Statements 
28-36/37/38-22
Safety Statements 
22-28-36/37-45-36-26-24/25
RIDADR 
UN 3462 6.1/PG 1
WGK Germany 
3
RTECS 
OP1927800
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M3547
Product name
Mangiferin from Mangifera indica bark
Packaging
1g
Price
$409
Updated
2024/03/01
Sigma-Aldrich
Product number
06279
Product name
Mangiferin
Purity
analytical standard
Packaging
10mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
22360
Product name
Mangiferin
Purity
≥98%
Packaging
100mg
Price
$41
Updated
2024/03/01
Cayman Chemical
Product number
22360
Product name
Mangiferin
Purity
≥98%
Packaging
1g
Price
$302
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0001751
Product name
Mangiferin
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001751
Price
$61.2
Updated
2024/03/01
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Mangiferin Chemical Properties,Usage,Production

Description

Mangiferin is a plant natural polyphenol of C-glycosylxanthone structure and various pharmacological activities. It can be found in many plant species, among which the mango tree (Mangifera indica) is one of the primary sources. Mangiferin is also present in some medicinal herbs, influencing their therapeutic and preventive properties, and in honeybush (Cyclopia sp.), a popular South African herbal tea. Mangiferin dissolves well in water, so it can be easily extracted into infusions and decoctions. In the mangiferin molecule, four aromatic hydroxyl groups determine its strong antiradical and antioxidant properties. Mangiferin is also an efficient iron chelator, therefore preventing the generation of hydroxyl radicals in Fenton-type reactions[1].

Chemical Properties

Yellow powder

Uses

MAO inhibitor, immunostimulant

Uses

Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes. Mangiferin has effect of hepatinica and choleretic, and is used to therapy hepatitis. Mangiferin is an anti-inflammatory, antivirotic, central nervous system inhibit function and immunologic suppression. Mangiferin has curative effect on chronic bronchitis. Mangiferin has cytotoxicity effect on hepatocellularcarcinoma ce1l, and may induce apoptosis. Mangiferin has the effect of antioxidation and delaying caducity.

Definition

ChEBI: A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position.

General Description

Mangiferin (MGF) is a natural bioactive polyphenol predominantly isolated from the Mangifera indica (Mango) tree. It has a xanthone glucoside structure. Mangiferin can also be found in other angiosperm plants and herbs.

Biochem/physiol Actions

Mangiferin has various pharmacological properties including antioxidant, anti-diabetic, anti-bacterial, cardioprotective, neuroprotective, and immunomodulatory activities. It has also displayed antidiabetic, antihyperlipidemic, and antiatherogenic properties in streptozotocin-induced diabetic rats. MGF exerts chemotherapeutic and chemo-preventative activities. It displays antioxidant, analgesic, and hepatoprotective activity against carbon tetrachloride-induced liver injury. MGF is a known accelerator of gastrointestinal transit (GIT).

References

[1] Adam Matkowski. “Mangiferin - a bioactive xanthonoid, not only from mango and not just antioxidant.” Mini reviews in medicinal chemistry 13 3 (2013): 439–55.

Mangiferin Preparation Products And Raw materials

Raw materials

Preparation Products

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Mangiferin Suppliers

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View Lastest Price from Mangiferin manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Mangiferin 4773-96-0
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-18
Changsha Staherb Natural Ingredients Co., Ltd.
Product
Mangiferin 4773-96-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
50%-98%
Supply Ability
1000kg
Release date
2022-11-09
Wuhan Circle Star Chem-medical Technology Co.,Ltd
Product
Mangiferin 4773-96-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98
Supply Ability
1000
Release date
2025-01-03

4773-96-0, MangiferinRelated Search:

Arbutin Andrographolide Asiaticoside Ursolic acid Taxifolin Neomangiferin Xanthone 2,4,4'-TRIHYDROXYBENZOPHENONE 1-(2-METHOXY-5-METHYLPHENYL)ETHANONE 2-HYDROXY-5-METHYLBENZOPHENONE 4-Phenoxyphenol 2,4-Dihydroxybenzophenone 2-(4-METHYLPHENOXY)BENZENECARBALDEHYDE 4-Hexylresorcinol 2,3',4,4'-TETRAHYDROXYBENZOPHENONE 2',4'-DIHYDROXY-3'-PROPYLACETOPHENONE 4,4'-Dihydroxybenzophenone (4-PHENOXYPHENYL)METHANOL

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