ChemicalBook > CAS DataBase List > 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE

4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE

Product Name
4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE
CAS No.
933-76-6
Chemical Name
4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE
Synonyms
AKOS B029262;Emorfazone int;4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE;2-Methyl-4,5-dichloro-3-pyridazinone;4,5-dichloro-2-methylpyridazine-3-one;5-Dichloro-2-Methyl-3(2H)-pyridazinone;5-Dichloro-2-methylpyridazin-3(2H)-one;4,5-dichloro-2-methyl-3(2h)-pyridazinon;4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE, 9&;4,5-DICHLORO-2-METHYL-3(2H)-PYRIDAZINONE
CBNumber
CB8728203
Molecular Formula
C5H4Cl2N2O
Formula Weight
179
MOL File
933-76-6.mol
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4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE Property

Melting point:
87-91 °C(lit.)
Boiling point:
197.2±50.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
soluble in Ethanol
form 
powder to crystal
pka
-3.57±0.20(Predicted)
color 
White to Orange to Green
InChI
InChI=1S/C5H4Cl2N2O/c1-9-5(10)4(7)3(6)2-8-9/h2H,1H3
InChIKey
ACKBTCUMGAHRIE-UHFFFAOYSA-N
SMILES
C1(=O)N(C)N=CC(Cl)=C1Cl
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-43
Safety Statements 
26-36
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
UR6188000
HazardClass 
6.1
HS Code 
29339980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
597716
Product name
4,5-Dichloro-2-methyl-3(2H)-pyridazinone
Purity
97%
Packaging
5g
Price
$149
Updated
2023/06/20
TCI Chemical
Product number
D5324
Product name
4,5-Dichloro-2-methyl-3(2H)-pyridazinone
Purity
>98.0%(GC)
Packaging
1g
Price
$23
Updated
2025/07/31
TCI Chemical
Product number
D5324
Product name
4,5-Dichloro-2-methyl-3(2H)-pyridazinone
Purity
>98.0%(GC)
Packaging
5g
Price
$90
Updated
2025/07/31
TRC
Product number
M299780
Product name
2-Methyl-4,5-dichloro-3-pyridazinone
Packaging
10g
Price
$115
Updated
2021/12/16
AK Scientific
Product number
J94295
Product name
4,5-Dichloro-2-methyl-3(2H)-pyridazinone
Packaging
1g
Price
$12
Updated
2021/12/16
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4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE Chemical Properties,Usage,Production

Chemical Properties

Off-white to yellow low crystalline powder

Uses

4,5-Dichloro-2-methyl-3(2H)-pyridazinone can be used in the synthesis of 4-amino-3(2H)-pyridazinones and 5-amino-3(2H)-pyridazinones via reaction with N-benzylaminoethanol.

Definition

ChEBI: 4,5-Dichloro-2-methyl-3(2H)-pyridazinone is a pyridazinone.

Synthesis

932-22-9

74-88-4

933-76-6

Step 1: A round bottom flask was charged with 4,5-dichloropyridazin-3(2H)-one (10.0 g, 60.6 mmol), potassium carbonate (16.8 g, 121.2 mmol), iodomethane (4.0 mL, 64.3 mmol) and acetonitrile (80 mL). The reaction mixture was heated to reflux for 12 hours and then cooled to room temperature. After completion of the reaction, the mixture was filtered and the filtrate was concentrated. The residue was purified by column chromatography (dichloromethane as eluent) to afford 4,5-dichloro-2-methylpyridazin-3-one 8.21 g (76% yield). The product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.18 (s, 1H), 3.70 (s, 3H); mass spectrum (m/z) = 179 ([M+H]+).

References

[1] Patent: WO2009/142732, 2009, A2. Location in patent: Page/Page column 61-62
[2] Patent: WO2011/15629, 2011, A1. Location in patent: Page/Page column 46; 47
[3] Journal of Heterocyclic Chemistry, 1996, vol. 33, # 6, p. 1579 - 1582
[4] Patent: WO2013/50421, 2013, A1. Location in patent: Page/Page column 37
[5] Journal of the Korean Chemical Society, 2014, vol. 58, # 1, p. 140 - 144

4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE Suppliers

Americas 1 Belgium 1 China 99 Europe 1 Germany 4 India 3 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 7 United States 17 Global 136
Tianyuan Natural Product Co.,Ltd.
Tel
028-85012281 13808177790
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86-28-85121102
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xianlihong8888@163.com
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China
ProdList
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SiChuang NanBu Honesty Technology Co., Ltd.
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0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
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China
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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0573-85285100
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isenchem@163.com
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China
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
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United States
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
Email
info@hanhongsci.com
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China
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China DongFan Chemical Co.,LTD
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86-0571-85151182
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86-0571-85151182
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China
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Shanghai Hope Chem Co., Ltd.，
Tel
+21-18501659228 18501659228
Fax
sales@hope-chem.com
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info@hope-chem.com
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China
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Thermo Fisher Scientific
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800-810-5118
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+86-10-84193589
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cnchemical@thermofisher.com
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China
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View Lastest Price from 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4,5-Dichloro-2-Methylpyridazin-3-one 933-76-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-04-29
Shanghai Rlavie Technology Co ltd
Product
4,5-Dichloro-2-Methylpyridazin-3-one 933-76-6
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
100kgs/month
Release date
2021-11-08
Dideu Industries Group Limited
Product
4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE 933-76-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-02

933-76-6, 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONERelated Search:

4,5-DICHLORO-2-(2-FLUOROBENZYL)PYRIDAZINE-3(2H)-ONE 2-(2-CHLORO-6-FLUOROBENZYL)-4,5-DICHLOROPYRIDAZINE-3-(2H)-ONE 1-PHENYL-4,5-DICHLORO-6-PYRIDAZONE 4,5-DICHLORO-2-(3,5-DICHLOROPHENYL)-2,3-DIHYDROPYRIDAZIN-3-ONE 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE 4,5-DICHLORO-2-(4-METHYLBENZYL)-2,3-DIHYDROPYRIDAZIN-3-ONE 4,5-DICHLORO-2-(HYDROXYMETHYL)-2,3-DIHYDROPYRIDAZIN-3-ONE 2-CHLOROMETHYL-4,5-DICHLOROPYRIDAZIN-3(2H)-ONE 4,5-dichloro-2-[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one 4,5-DICHLORO-2-(4-METHYLPHENYL)-2,3-DIHYDROPYRIDAZIN-3-ONE 2-(3-CHLORO-4-FLUOROPHENYL)-4,5-DICHLORO-PYRIDAZINE-3-(2H)-ONE 4,5-DICHLORO-2-(2,6-DICHLOROBENZYL)-2,3-DIHYDROPYRIDAZIN-3-ONE 4,5-DICHLORO-2-(2,4-DICHLOROPHENYL)-2,3-DIHYDROPYRIDAZIN-3-ONE 2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE 4,5-DICHLORO-2-(4-CHLOROBENZYL)-2,3-DIHYDROPYRIDAZIN-3-ONE 4,5-DICHLORO-6-HYDROXY-2-(2-HYDROXYETHYL)-2,3-DIHYDROPYRIDAZIN-3-ONE (4,5-DICHLORO-6-OXO-1,6-DIHYDROPYRIDAZIN-1-YL)METHYL BENZOATE 4,5-DICHLORO-6-HYDROXY-2-[2-HYDROXY-3-(METHYLTHIO)PROPYL]-2,3-DIHYDROPYRIDAZIN-3-ONE

  • 4,5-dichloro-2-methyl-3(2h)-pyridazinon
  • 4,5-DICHLORO-2-METHYLPYRIDAZIN-3[2H]-ONE
  • 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE
  • 4,5-DICHLORO-2-METHYLPYRIDAZINE-3(2H)-ONE
  • 4,5-DICHLORO-2-METHYL-2,3-DIHYDROPYRIDAZIN-3-ONE
  • 4,5-DICHLORO-2-METHYL-2H-PYRIDAZIN-3-ONE
  • 4,5-DICHLORO-2-METHYL-3(2H)-PYRIDAZINONE
  • AKOS B029262
  • 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE, 9&
  • 4,5-DICHLORO-2-METHYLPYRIDAZIN-3[2H]-ONE 98%
  • 4,5-Dichloro-2-methylpyridazin-32Hü-one, 98%
  • 4,5-Dichloro-2-methyl-3(2H)-pyridazinone,97%
  • 5-Dichloro-2-Methyl-3(2H)-pyridazinone
  • Emorfazone int
  • CCM, 4,5-Dichloro-2,3-dihydro-2-methylpyridazin-3-one
  • 4,5-Dichloro-2,3-dihydro-2-methyl-3-oxopyridazine, 4,5-Dichloro-2,3-dihydro-2-methyl-3-oxo-1,2-diazine
  • 2-Methyl-4,5-dichloro-3-pyridazinone
  • 4,5-dichloro-2-methylpyridazine-3-one
  • 3(2H)-Pyridazinone, 4,5-dichloro-2-methyl-
  • 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE ISO 9001：2015 REACH
  • 5-Dichloro-2-methylpyridazin-3(2H)-one
  • 4,5-Dichloro-2-methyl-3(2<i>H</i>)-pyridazinone
  • 933-76-6
  • 933-76-3
  • Building Blocks
  • Pyridazines
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Building Blocks
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridazines
  • Halides
  • Pyrazines, Pyrimidines & Pyridazines
  • Pyrazines, Pyrimidines & Pyridazines