1,1,2-Trichlorotrifluoroethane Property

Melting point:

−35 °C(lit.)

Boiling point:

47-48 °C(lit.)

Density 

1.57 g/mL at 25 °C(lit.)

vapor density 

6.5 (vs air)

vapor pressure 

5.5 psi ( 20 °C)

refractive index 

n20/D 1.358(lit.)

Flash point:

195°C

storage temp. 

2-8°C

solubility 

0.17g/l

form 

Colorless gas; volatile liquid.

Water Solubility 

0.02 g/100 mL. Slightly soluble

BRN 

1740335

Henry's Law Constant

0.154, 0.215, 0.245, 0.319, and 0.321 at 10, 15, 20, 25, and 30 °C, respectively (EPICS, Ashworth et al., 1988)

Exposure limits

TLV-TWA 1000 ppm (～7600 mg/m³) (ACGIH, MSHA, and OSHA); TLV-STEL 1250 ppm (ACGIH).

Dielectric constant

2.6（21℃）

Stability:

Stable. Non-flammable. Incompatible with alkali metals, chemically active metals, magnesium, zinc, aluminium.

LogP

3.160

CAS DataBase Reference

76-13-1(CAS DataBase Reference)

NIST Chemistry Reference

Ethane, 1,1,2-trichloro-1,2,2-trifluoro-(76-13-1)

EPA Substance Registry System

CFC-113 (76-13-1)

Safety

Hazard Codes 

N,Xi,T,F

Risk Statements 

52/53-59-39/23/24/25-23/24/25-51/53-11

Safety Statements 

59-61-45-36/37-16

RIDADR 

UN 3082 9/PG 3

WGK Germany 

2

RTECS 

KJ4000000

Autoignition Temperature

1256 °F

Hazard Note 

Irritant

Hazardous Substances Data

76-13-1(Hazardous Substances Data)

Toxicity

Acute oral LD50 for rats 43 mg/kg (quoted, RTECS, 1985).

IDLA

2,000 ppm

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

H420Harms public health and the environment by destroying ozone in the upper atmosphere

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P502Refer to manufacturer/supplier for information on recovery/recycling

1,1,2-Trichlorotrifluoroethane Chemical Properties,Usage,Production

Chemical Properties

colourless liquid or gas

Chemical Properties

TTE is a colorless liquid. Carbon tetrachloride-like odor at high concentrations. A gas above 48℃.

Physical properties

Clear, colorless liquid with a carbon tetrachloride-like odor at high concentrations

Uses

1,1,2-Trichloro-1,2,2-trifluoroethane is usedas a refrigerant and as a drycleaning solvent.It is also used as an extraction solvent foranalyzing petroleum hydrocarbons, oils, andgreases.

Uses

Dry-cleaning solvent, fire extinguishers, to make chlorotrifluoroethylene, blowing agent, polymer intermediate, solvent drying, drying electronic parts and precision equipment.

Uses

Solvent for cleaning electronic equipment and degreasing of machinery; refrigerant; dry cleaning agent.

Definition

ChEBI: 1,1,2-Trichlorotrifluoroethane is a chlorofluorocarbon and a haloalkane. It has a role as a refrigerant.

General Description

Colorless liquid with a sweet, ether-like odor. Sinks in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1,1,2-Trichlorotrifluoroethane yields violent reactions with Al, Ba, Li, Sm, Na/K alloy and Ti . May react exothermically with aluminum.

Health Hazard

Inhalation causes irritation of the nose, throat, and lungs. High concentrations may cause death by respiratory failure or asphyxiation. May produce superficial skin burns or defatting type dermatitis and may irritate the eyes.

Health Hazard

The acute oral toxicity of this compoundis very low. The oral LD50 value in ratsis 43,000 mg/kg. The inhalation toxicity isalso low. Exposure to high concentrationscan produce a weak narcotic effect, car diac sensitization, and irritation of respi ratory passage. Chronic exposure causedliver enlargement in rats. A 6-hour expo sure to 87,000 ppm of 1,1,2-trichloro-1,2,2-trifluoroethane was lethal to rats. Ingestionof the liquid may cause nausea, lethargy,nervousness, and tremor. The irritant actionof the liquid was mild on rabbits’ skin.

Fire Hazard

Noncombustible liquid.

Industrial uses

1,1,2-Trichlorotrifluoroethane (CFC 113) is generally a stable molecule not prone to the reactivity that is often shown by the chlorinated hydrocarbons. The solvent blends that contain the fluorinated hydrocarbon and an alcohol display some metal reactivity which is inhibited by adding nitromethane as a stabilizer.

Safety Profile

Mildly toxic by ingestion and inhalation. Affects the central nervous system in humans. A sktn irritant. Combustible when exposed to heat or flame. Incompatible with Al, Ba, Li, Sm, NaK alloy, Ti. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and FLUORIDES.

Potential Exposure

TTE is used as a solvent and refrigerant; it is used in fire extinguishers; as a blowing agent and as an intermediate in the production of chlorotrifluoroethylene monomer by reaction with zinc.

Carcinogenicity

A 2 year inhalation toxicity study/carcinogenicity study was conducted by Trochimowicz et al. in which groups of 100 male and 100 female rats were exposed to levels of up to of
20,000 ppm of CFC 113 6 h/day, 5 days/week for 2 years. Although five nasal tumors were seen, one at 20,000 ppm and four at 10,000 ppm, all five were different morphological types and were judged not to be exposure related. In addition, there was a small increase (5.8%) in pancreatic islet cell adenomas in the females exposed to 20,000 ppm; however, this was within the normal control range.
In a second study, injection of 0.1mLof 10% CFC 113 was not carcinogenic. But when given with a 5% solution of piperonyl butoxide, hepatomas were induced in male mice. The significance of this experimental finding has never been determined.

Environmental Fate

Biological. In an anoxic aquifer beneath a landfill in Ottawa, Ontario, Canada, there was evidence to suggest that 1,1,2-trichlorotrifluoroethane underwent reductive dehalogenation to give 1,2-difluoro-1,1,2-trichloroethylene and 1,2-dichloro-1,1,2-trifluoroethane. It was proposed that the latter compound was degraded via dehydrodehalogenation to give 1-chloro-1,1,2-trifluoroethylene (Lesage et al., 1990).
Chemical/Physical. 1,1,2-Trichlorotrifluoroethane will not hydrolyze to any reasonable extent (Kollig, 1993).

Shipping

UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Purification Methods

Wash it with water, then with weak alkali. Dry it with CaCl2 or H2SO4 and distil it. [Locke et al. J Am Chem Soc 56 1726 1934, Beilstein 1 III 157, 1 IV 142.]

Incompatibilities

Violent reaction with chemically active metals (such as powdered aluminum; beryllium, magnesium and zinc); calcium. Contact with alloys containing more than 2% magnesium causes decomposition, releasing hydrogen chloride, hydrogen fluoride; and carbon monoxide. May react exothermically with aluminum.

Waste Disposal

Incineration, preferably after mixing with another combustible fuel. Care must be exercised to assure complete combustion to prevent the formation of phosgene. An acid scrubber is necessary to remove the halo acids produced.