2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
- Product Name
- 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
- CAS No.
- 58632-95-4
- Chemical Name
- 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
- Synonyms
- BOC-ON;2-(BOC-OXYIMINO)-2-PHENYLACETONITRILE;Boc-On99%;Boc-ON, 98+%;BOC-ON, 99% 5GR;BOC-ON, 99% 25GR;2-(tert-Butoxycarbon;LABOTEST-BB LT00159655;2-(Boc-oxyimino)-2-phenylacetonitrile 99%;tert-butyl alpha-cyanobenzylaminyl carbonate
- CBNumber
- CB8741235
- Molecular Formula
- C13H14N2O3
- Formula Weight
- 246.26
- MOL File
- 58632-95-4.mol
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile Property
- Melting point:
- 85-88 °C (lit.)
- Boiling point:
- 389.26°C (rough estimate)
- Density
- 1.1855 (rough estimate)
- refractive index
- 1.6450 (estimate)
- storage temp.
- -20°C
- solubility
- Soluble in water or 1% acetic acid
- form
- Fine Crystalline Powder
- color
- White to slightly beige
- Water Solubility
- insoluble
- Sensitive
- Moisture Sensitive
- BRN
- 2217296
- CAS DataBase Reference
- 58632-95-4(CAS DataBase Reference)
- EPA Substance Registry System
- Benzeneacetonitrile, .alpha.-[[[(1,1-dimethylethoxy)carbonyl]oxy]imino]- (58632-95-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 22-24/25-36/37/39-26-36
- RIDADR
- 3276
- WGK Germany
- 3
- RTECS
- DA0513600
- F
- 10-21
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29280090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 193372
- Product name
- 2-(Boc-oxyimino)-2-phenylacetonitrile
- Purity
- 99%
- Packaging
- 5g
- Price
- $27.18
- Updated
- 2024/03/01
- Product number
- 193372
- Product name
- 2-(Boc-oxyimino)-2-phenylacetonitrile
- Purity
- 99%
- Packaging
- 25g
- Price
- $48.5
- Updated
- 2024/03/01
- Product number
- B0988
- Product name
- 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
- Purity
- >98.0%(N)
- Packaging
- 5g
- Price
- $25
- Updated
- 2024/03/01
- Product number
- B0988
- Product name
- 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
- Purity
- >98.0%(N)
- Packaging
- 25g
- Price
- $73
- Updated
- 2024/03/01
- Product number
- A18906
- Product name
- Boc-ON, 98+%
- Packaging
- 5g
- Price
- $33.65
- Updated
- 2024/03/01
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile Chemical Properties,Usage,Production
Chemical Properties
White to off-white microcrystalline powder
Uses
Widely used for protection of amino groups in peptide synthesis and multi-step organic synthesis of small molecules.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 6, p. 199, 1988
Tetrahedron Letters, 16, p. 4393, 1975 DOI: 10.1016/S0040-4039(00)91133-X
Purification Methods
Triturate the solid with 90% aqueous MeOH, filter, wash with 90% aqueous MeOH and dry it in a vacuum. Recrystallise it from MeOH (needles or plates), but use warm MeOH and cool to crystallise; do not boil as it decomposes slowly. IR has max 1785 (C=O) cm-1 and NMR (CDCl3) usually shows two tert-butyl singlets for syn and anti isomers. Store it in a brown bottle (fridge). It evolves CO2 at room temperature (stoppered bottle can explode!), but can be stored over silica gel which may extend its useful life to more than a year. [Itoh et al. Org Synth 59 95 1980.]
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23680
- Advantage
- 75
View Lastest Price from 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile manufacturers
- Product
- 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 58632-95-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-26
- Product
- 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 58632-95-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 58632-95-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08