Cyclic AMP

ChemicalBook > CAS DataBase List > Cyclic AMP

Product Name: Cyclic AMP
CAS No.: 60-92-4
Chemical Name: Cyclic AMP
Synonyms: CAMP;ADENOSINE CYCLOPHOSPHATE;Acrasin;ADENOSINE CYCLPHOSPHATE;(4aR,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide;3:5-CAMP;Cyclo-AMP;CYCLIC AMP;3',5'-cAMPH;Adenosine 3'
CBNumber: CB8747868
Molecular Formula: C10H12N5O6P
Formula Weight: 329.21
MOL File: 60-92-4.mol

Less

Cyclic AMP Property

Melting point:: 260 °C (dec.)(lit.)
alpha: -53.7 º (c=0.7,water)
Boiling point:: 56.12°C
Density: 2.47±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: H₂O: 10 mg/mL pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20×
pka: 1.00±0.60(Predicted)
form: powder
color: white
Water Solubility: 50 mg/mL
Merck: 14,2708
BRN: 52645
Stability:: Hygroscopic
NIST Chemistry Reference: Adenosine 3',5'-cyclic monophosphate(60-92-4)
EPA Substance Registry System: Adenosine, cyclic 3',5'-(hydrogen phosphate) (60-92-4)

Less

Safety

Hazard Codes: C,Xi
Risk Statements: 34-36/37/38
Safety Statements: 22-24/25-45-36/37/39-26-36
WGK Germany: 3
RTECS: AU7357600
F: 10-21
TSCA: Yes
HS Code: 29349990
Toxicity: oms-hmn:oth 100 mmol/L JIDEAE 65,52,75

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A9501
Product name: Adenosine 3′,5′-cyclic monophosphate
Purity: ≥98.5% (HPLC), powder
Packaging: 1g
Price: $295
Updated: 2024/03/01

Sigma-Aldrich

Product number: A9501
Product name: Adenosine 3′,5′-cyclic monophosphate
Purity: ≥98.5% (HPLC), powder
Packaging: 5g
Price: $1120
Updated: 2024/03/01

TCI Chemical

Product number: A2381
Product name: Adenosine 3',5'-Cyclic Monophosphate Hydrate
Purity: >99.0%(HPLC)
Packaging: 1g
Price: $86
Updated: 2024/03/01

TCI Chemical

Product number: A2381
Product name: Adenosine 3',5'-Cyclic Monophosphate Hydrate
Purity: >99.0%(HPLC)
Packaging: 5g
Price: $274
Updated: 2024/03/01

Alfa Aesar

Product number: J60936
Product name: Adenosine-3',5'-cyclic monophosphate, 98%
Packaging: 1g
Price: $151
Updated: 2024/03/01

Less

Cyclic AMP Chemical Properties,Usage,Production

Chemical Properties

White crystalline or Pale yellow powder; odorless. Slightly soluble in water, almost insoluble in ethanol or ether.

Uses

cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3': 5'-cyclic monophosphate. In the presence of adenosine 3':5'-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3':5'-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3',5'-cyclic monophosphate.

Definition

ChEBI: Cyclic AMP is a 3',5'-cyclic purine nucleotide having having adenine as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an adenyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic AMP(1-).

General Description

Cyclic AMP is a second messenger molecule comprised of an adenine ribonucleotide bearing a phosphate group bound to the oxygen molecules at the 3' and 5' positions of the sugar moiety. Cyclic AMP, which is synthesized from ATP by the intracellular enzyme adenylate cyclase, modulates the activity of several hormone-dependent signal transduction pathways.

Biochem/physiol Actions

Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.

Safety Profile

Human mutation data reported.When heated to decomposition it emits toxic fumes ofPOx and NOx.

Synthesis

Cyclic AMP is synthesized from ATP by adenylate cyclase located on the inner side of the plasma membrane and anchored at various locations in the interior of the cell.[1] Adenylate cyclase is activated by a range of signaling molecules through the activation of adenylate cyclase stimulatory G (Gs)-protein-coupled receptors. Adenylate cyclase is inhibited by agonists of adenylate cyclase inhibitory G (Gi)-protein-coupled receptors. Liver adenylate cyclase responds more strongly to glucagon, and muscle adenylate cyclase responds more strongly to adrenaline.
cAMP decomposition into AMP is catalyzed by the enzyme phosphodiesterase.

Cyclic AMP Preparation Products And Raw materials

Raw materials

Moroxydine Dicyclohexylcarbodide or CDCC Styrene cation exchange resin Anhydrous pyridine Water pump Ammonium bicarbonate Dicyclohexylcarbodiimide

Preparation Products

6-Thioguanine

Less

Cyclic AMP Suppliers

Americas 1 Belgium 2 China 429 Czech Republic 1 Europe 4 Germany 7 India 9 Italy 1 Japan 3 Switzerland 4 Ukraine 1 United Kingdom 15 United States 48 Global 525

Yantai Xianhua Chemical Technology Co., Ltd (HSBC Shandong Yantai Fine Chemical Co., Ltd.)

Tel: 18754503080
Email: sunzhulin@xhtechgroup.com
Country: China
ProdList: 103
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4941
Advantage: 60

Watson Biotechnology Co.,Ltd

Tel: 027-027-59207879 18140587686
Fax: QQ：1972026995
Email: kf@3600chem.com
Country: China
ProdList: 4699
Advantage: 55

Hangzhou Weitai Biological Pharmaceutical Co., Ltd.

Tel: 0571-82358004 13588879771
Email: info@weitai-pharmaceutical.com
Country: China
ProdList: 81
Advantage: 58

Shanghai GaoLang Chemical Technology Co., Ltd.

Tel: 021-57340939 18017297327
Fax: 021-37210791
Email: sales@gaolangchemical.com
Country: China
ProdList: 888
Advantage: 55

Hangzhou Meiya Pharmaceutical Co.,ltd.

Tel: 021-33686691
Email: lijh@meiyapharm.com
Country: China
ProdList: 50
Advantage: 58

Anhui Chnbio Technology Co., Ltd.

Tel: 18969017660
Email: 2424422732@qq.com
Country: China
ProdList: 68
Advantage: 58

Shanghai xinchenfa Chemical Technology Co.,Ltd

Tel: 021-13564487020 13564487020
Email: 3546809660@qq.com
Country: China
ProdList: 488
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1998
Advantage: 65

Hongene Biotech Corporation

Tel: 021-64757213
Fax: 86-21-64700613
Email: info@hongene.com
Country: China
ProdList: 672
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 17987
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3296
Advantage: 57

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18739
Advantage: 57

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14443
Advantage: 57

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

Nanjing Asian Chemical Co., Ltd.

Tel: +86 (25) 82263158
Fax: +86 (25) 82263168
Country: China
ProdList: 262
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9725
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9872
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17779
Advantage: 75

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6139
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22519
Advantage: 55

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9552
Advantage: 55

Nanjing Dulai Biotechnology Co., Ltd.

Tel: 025-84699383-8003 18013301590
Fax: 025-84699383-8003
Email: njduly@126.com
Country: China
ProdList: 973
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8033
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3750
Advantage: 55

Zouping Mingxing Chemical Co.,Ltd.

Tel: 86-13605431940 13605431940
Fax: 0086-0543-2240079
Email: zpmxchemical@126.com
Country: China
ProdList: 2002
Advantage: 62

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Wuhan DKY Technology Co.,Ltd.

Tel: 27-81302488 18007166089
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 2024
Advantage: 58

Hubei XinyuanShun Chemical Co., Ltd.

Tel: 13971561712, 13995564702, 027-50664929
Fax: 027-50664927
Email: hbeixys2001@163.com
Country: China
ProdList: 3123
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9986
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

Shanghai DiBai Chemicals Co., Ltd.

Tel: 021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
Country: China
ProdList: 3993
Advantage: 60

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9352
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9636
Advantage: 58

Shanghai CanSpecsci Instrument Co., Ltd.

Tel: 400-6087598 15021221957
Fax: 4006087598-8012
Email: order@canspecsci.com
Country: China
ProdList: 2071
Advantage: 56

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4619
Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4951
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10287
Advantage: 55

Founding chemical products Technology Development Co., Ltd.

Tel: 0310-6697998 03106697998
Fax: 0310-6697696
Email: losartan@crotonic-anhydride.com
Country: China
ProdList: 96
Advantage: 58

Less

View Lastest Price from Cyclic AMP manufacturers

Henan Fengda Chemical Co., Ltd

Product: Adenosine 3`, 5`-cyclic monophosphate 60-92-4
Price: US $5.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-16

Hangzhou Meiya Pharmaceutical Co Ltd

Product: Adenosine 3’,5’-cyclic monophosphate (cAMP) 60-92-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥98%
Supply Ability: 20 MT
Release date: 2024-02-06

Hebei Duling International Trade Co. LTD

Product: Adenosine Cyclophosphate 60-92-4
Price: US $100.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100 tons
Release date: 2022-09-28

60-92-4, Cyclic AMPRelated Search:

phosphate ester starch Vidarabine monophosphate Clindamycin phosphate Adenosine Dibutyryl adenosine cyclophosphate calcium SULPHOSUCCINIC ACID ESTER ADP Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) ADENOSINE 5'-TRIPHOSPHATASE Adenosine 5'-monophosphate Adenosine 3',5'-cyclic monophosphate sodium salt Adenosine-5'-diphosphate disodium salt ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& ADENOSINE 5'-DIPHOSPHATE MONOPOTASSIUM SALT Adenosine-5'-diphosphate trilithium salt ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT 5'-Tosyladenosine ATP disodium salt

adenosine 3',5'-phosphate monohydrate

CAMP

CAMP, ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE

CYCLIC AMP

CYCLIC AMP-3',5'

5’-cyclicmonophosphate

6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide

Acrasin

Adenosine 3',5'-cyclophosphate

Adenosine 3',5'-phosphate

Adenosine cyclic 3',5'-monophosphate

Adenosine cyclic 3',5'-phosphate

Adenosine cyclic monophosphate

Adenosine, cyclic 3',5'-(hydrogen phosphate)

adenosine,cyclic3’,5’-(hydrogenphosphate)

adenosine3’,5’-cyclophosphate

adenosine3’,5’-phosphate

adenosinecyclic3’,5’-phosphate

adenosinecyclicmonophosphate

adenosinecyclicphosphate,cyclicamp

Cyclic 3',5'-adenylic acid

Cyclic adenosine 3',5'-monophosphate

Cyclic adenosine 3',5'-phosphate

cyclic3’,5’-(hydrogenphosphate)-adenosin

ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE*HPL C MARKER

ADENOSINE 3':5'-CYCLIC MONOPHOSPHATEFREE ACID

(-)-ADENOSIN-3',5'-CYCLOPHOSPHORSAEURE 9

ADENOSINE CYCLPHOSPHATE

Adenosine 3',5'-hydrogen phosphate

Adenosine 3'-,5'-cyclic monophosphate, 99+%

Adenosine-3’,5’-cyclic phosphoric acid

cyclic 3',5'-(hydrogen phosphate)Adenosine

Adenosine-3'',5''-monophosphoric acid

3'-5' Cyclic adenosine monophosphate

CYCLIC-AMP (ADENOSINE 3'', 5''-CYCLIC MONOPHOSPHATE)

ADENOSINE-3,5-CYCLICMONOPHOSPHPRIC ACID extrapure for biochemistry

3μ,5μ-Cyclic AMP, Adenosine 3μ,5μ-cyclophosphate, cAMP

Cyclic Adenosine Monophosphate (cAMP)

3',5'-cAMP Hydrate

cyclic3’,5’-adenylicacid

cyclic3’,5’-amp

cyclicadenosine3’,5’-phosphate

(S)-CYCLIC 3' 5'-(HYDROGEN PHOSPHATE) ADENOSINE

ADENOSINE CYCLICPHOSPHATE

ADENOSINE CYCLOPHOSPHATE

(-)-ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE

ADENOSINE 3'-,5'-CYCLIC MONOPHOSPHATE

ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE

ADENOSINE-3',5'-CYCLIC-MONOPHOSPHORIC ACID

ADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID

ADENOSINE-3':5'-CYCLIC PHOSPHATE

ADENOSINE-3',5'-CYCLIC PHOSPHATE H2O

ADENOSINE-3',5'-CYCLOPHOSPHORIC ACID

ADENOSINE 3'5'-MONOPHOSPHATE

ADENOSINE-3':5'-PHOSPHATE CYCLIC

3:5-CAMP

3',5'-CYCLIC AMP

3',5'-Cyclic adenylphosphoric acid