Toloxatone

Product Name: Toloxatone
CAS No.: 29218-27-7
Chemical Name: Toloxatone
Synonyms: Humoryl;69276MD;Perenum;MD-69276;Toloxatone;Taloxotone;Delalande 69276;Toloxatone USP/EP/BP;Toloxatone - MD 69276;ToloxatonetoloxatonetoloxatoneToloxatone
CBNumber: CB8752750
Molecular Formula: C11H13NO3
Formula Weight: 207.23
MOL File: 29218-27-7.mol

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Toloxatone Property

Melting point:: 76°
Boiling point:: 358.9±21.0 °C(Predicted)
Density: 1.245±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO: >10mg/mL
form: solid
pka: 14.05±0.10(Predicted)
color: White to off-white

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Safety

Hazard Codes: Xn
Risk Statements: 22
RIDADR: 3249
WGK Germany: 3
RTECS: RQ2867500
HazardClass: 6.1(b)
PackingGroup: III
Toxicity: LD50 orally in mice (mg/kg): 1850 (Fauran); also reported as 1500 (Raynaud)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T3452
Product name: Toloxatone
Purity: ≥98% (HPLC), solid
Packaging: 10mg
Price: $119
Updated: 2024/03/01

Sigma-Aldrich

Product number: T3452
Product name: Toloxatone
Purity: ≥98% (HPLC), solid
Packaging: 50mg
Price: $536
Updated: 2024/03/01

Usbiological

Product number: 467706
Product name: Toloxatone
Packaging: 10mg
Price: $340
Updated: 2021/12/16

TRC

Product number: T537005
Product name: Toloxatone
Packaging: 250mg
Price: $1865
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573423
Product name: Toloxatone (MD 69276)
Packaging: 1g
Price: $2023
Updated: 2021/12/16

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Toloxatone Chemical Properties,Usage,Production

Description

Toloxatone is a selective, reversible and competitive inhibitor of type A monoamine oxidase (MAO-A) which shows clinical utility as an antidepressant. It is reportedly free of the "cheese effect" in man, possibly due to the reversible nature of its inhibitory effect on intestinal MAO-A in the presence of high concentrations of tyramine.

Originator

Delalande (France)

Uses

Toloxatone is a monoamine oxidase-A (MAO-A) inhibitor.

Definition

ChEBI: 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one is a member of the class of oxazolidinones that is 5-(hydroxymethyl)-1,3-oxazolidin-2-one substituted by a 3-methylphenyl group at position 3. It is a member of toluenes, an oxazolidinone and a primary alcohol.

brand name

HUMORYL

Toloxatone Preparation Products And Raw materials

Raw materials

m-Toluidine Methyl chloroformate Propylene glycol Propylene oxide

Preparation Products

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Toloxatone Suppliers

China 30 Germany 1 United Kingdom 2 United States 12 Global 45

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View Lastest Price from Toloxatone manufacturers

Dideu Industries Group Limited

Product: Toloxatone 29218-27-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-26

29218-27-7, ToloxatoneRelated Search:

Duloxetine Toloxatone HYDROXYPROPYLCARBAMATE 2-Oxazolidinone, 5-hydroxymethyl-3-(m-tolyl)-, carbamate 3-PHENYL-2-OXAZOLIDINONE

2-OXAZOLIDINONE, 5-(HYDROXYMETHYL)-3-(3-METHYLPHENYL)-

Toloxatone

ToloxatonetoloxatonetoloxatoneToloxatone

5-Hydroxymethyl-3-(3-methylphenyl)oxazolidin-2-one

Humoryl

MD-69276

Perenum

5-(Hydroxymethyl)-3-(m-tolyl)oxazolidin-2-one

5-Hydroxymethyl-3-(m-tolyl)oxazolidin-2-one

69276MD

Delalande 69276

Taloxotone

5-(hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone

Toloxatone - MD 69276

Toloxatone USP/EP/BP

Toloxatone,Monoamine Oxidase,MD69276,MD-69276,MAO,inhibit,Inhibitor

29218-27-7