2-(1H-PYRAZOL-4-YL)-ETHANOL
- Product Name
- 2-(1H-PYRAZOL-4-YL)-ETHANOL
- CAS No.
- 180207-57-2
- Chemical Name
- 2-(1H-PYRAZOL-4-YL)-ETHANOL
- Synonyms
- Albb-003724;AKOS B018513;CHEMBRDG-BB 4000128;ART-CHEM-BB B018513;1H-PYRAZOLE-4-ETHANOL;2-(4-Pyrazolyl)ethanol;2-(1H-PYRAZOL-4-YL)-ETHANOL;2-(1H-pyrazole-4-yl)ethanol;4-(2-Hydroxyethyl)-1H-pyrazole;1H-Pyrazole-4-ethanol (9CI, ACI)
- CBNumber
- CB8755195
- Molecular Formula
- C5H8N2O
- Formula Weight
- 112.13
- MOL File
- 180207-57-2.mol
2-(1H-PYRAZOL-4-YL)-ETHANOL Property
- Melting point:
- 54-55 °C
- Boiling point:
- 140-145 °C(Press: 0.3 Torr)
- Density
- 1.228±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- 14.34±0.50(Predicted)
- color
- Yellow
- InChI
- InChI=1S/C5H8N2O/c8-2-1-5-3-6-7-4-5/h3-4,8H,1-2H2,(H,6,7)
- InChIKey
- YVQFZSHMTCZYMI-UHFFFAOYSA-N
- SMILES
- N1C=C(CCO)C=N1
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B529785
- Product name
- 2-(1H-Pyrazol-4-yl)ethanol
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B529785
- Product name
- 2-(1H-Pyrazol-4-yl)ethanol
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B529785
- Product name
- 2-(1H-Pyrazol-4-yl)ethanol
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 030963
- Product name
- 2-(1H-Pyrazol-4-yl)ethanol
- Packaging
- 500mg
- Price
- $26
- Updated
- 2021/12/16
- Product number
- J56411
- Product name
- 2-(1H-pyrazol-4-yl)ethanol
- Packaging
- 1g
- Price
- $54
- Updated
- 2021/12/16
2-(1H-PYRAZOL-4-YL)-ETHANOL Chemical Properties,Usage,Production
Synthesis
177940-20-4
180207-57-2
General procedure for the synthesis of 2-(1H-pyrazol-4-yl)ethanol from 3-(diethoxymethyl)-2-ethoxytetrahydrofuran: To intermediate 47A (30.00 g, 137.00 mmol) was slowly added hydrazine dihydrochloride (18.75 g, 179.00 mmol) dissolved in a mixture of water (50 mL) and ethanol (25 mL) at 0 °C. solution. The reaction mixture was stirred at 0°C for 1 hour and then continued to stir at room temperature for 1 hour. Sodium carbonate (30.00 g) was added to the reaction mixture and then evaporated to dryness under reduced pressure. The residue was washed with ethanol (10 mL) and evaporated again to give Intermediate 47B (15.00 g, 92% yield) as a brown oil. The product was analyzed by 'HNMR (400 MHz, CDCI3) with chemical shifts of 6 ppm 2.78 (t, J=6.38 Hz, 2H), 3.72 (d, J=7.25 Hz, 1H), 3.77-3.88 (m, 2H), 7.49 (s, 2H), and 9.52-10.74 (m, 1H).The LCMS analysis (Method-i) showed a retention time of 0.40 min and [M-H]- peak of 113.0.
References
[1] Patent: WO2018/93569, 2018, A1. Location in patent: Page/Page column 134
[2] Journal of the American Chemical Society, 1953, vol. 75, p. 4048,4050
2-(1H-PYRAZOL-4-YL)-ETHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(1H-PYRAZOL-4-YL)-ETHANOL manufacturers
- Product
- 2-(1H-PYRAZOL-4-YL)-ETHANOL 180207-57-2
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg,10kg,100kg
- Release date
- 2020-01-09