ChemicalBook > CAS DataBase List > 2-(1H-PYRAZOL-4-YL)-ETHANOL

2-(1H-PYRAZOL-4-YL)-ETHANOL

Product Name
2-(1H-PYRAZOL-4-YL)-ETHANOL
CAS No.
180207-57-2
Chemical Name
2-(1H-PYRAZOL-4-YL)-ETHANOL
Synonyms
Albb-003724;AKOS B018513;CHEMBRDG-BB 4000128;ART-CHEM-BB B018513;1H-PYRAZOLE-4-ETHANOL;2-(4-Pyrazolyl)ethanol;2-(1H-PYRAZOL-4-YL)-ETHANOL;2-(1H-pyrazole-4-yl)ethanol;4-(2-Hydroxyethyl)-1H-pyrazole;1H-Pyrazole-4-ethanol (9CI, ACI)
CBNumber
CB8755195
Molecular Formula
C5H8N2O
Formula Weight
112.13
MOL File
180207-57-2.mol
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2-(1H-PYRAZOL-4-YL)-ETHANOL Property

Melting point:
54-55 °C
Boiling point:
140-145 °C(Press: 0.3 Torr)
Density 
1.228±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
14.34±0.50(Predicted)
color 
Yellow
InChI
InChI=1S/C5H8N2O/c8-2-1-5-3-6-7-4-5/h3-4,8H,1-2H2,(H,6,7)
InChIKey
YVQFZSHMTCZYMI-UHFFFAOYSA-N
SMILES
N1C=C(CCO)C=N1
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2933199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B529785
Product name
2-(1H-Pyrazol-4-yl)ethanol
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
B529785
Product name
2-(1H-Pyrazol-4-yl)ethanol
Packaging
50mg
Price
$60
Updated
2021/12/16
TRC
Product number
B529785
Product name
2-(1H-Pyrazol-4-yl)ethanol
Packaging
100mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
030963
Product name
2-(1H-Pyrazol-4-yl)ethanol
Packaging
500mg
Price
$26
Updated
2021/12/16
AK Scientific
Product number
J56411
Product name
2-(1H-pyrazol-4-yl)ethanol
Packaging
1g
Price
$54
Updated
2021/12/16
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2-(1H-PYRAZOL-4-YL)-ETHANOL Chemical Properties,Usage,Production

Synthesis

177940-20-4

180207-57-2

General procedure for the synthesis of 2-(1H-pyrazol-4-yl)ethanol from 3-(diethoxymethyl)-2-ethoxytetrahydrofuran: To intermediate 47A (30.00 g, 137.00 mmol) was slowly added hydrazine dihydrochloride (18.75 g, 179.00 mmol) dissolved in a mixture of water (50 mL) and ethanol (25 mL) at 0 °C. solution. The reaction mixture was stirred at 0°C for 1 hour and then continued to stir at room temperature for 1 hour. Sodium carbonate (30.00 g) was added to the reaction mixture and then evaporated to dryness under reduced pressure. The residue was washed with ethanol (10 mL) and evaporated again to give Intermediate 47B (15.00 g, 92% yield) as a brown oil. The product was analyzed by 'HNMR (400 MHz, CDCI3) with chemical shifts of 6 ppm 2.78 (t, J=6.38 Hz, 2H), 3.72 (d, J=7.25 Hz, 1H), 3.77-3.88 (m, 2H), 7.49 (s, 2H), and 9.52-10.74 (m, 1H).The LCMS analysis (Method-i) showed a retention time of 0.40 min and [M-H]- peak of 113.0.

References

[1] Patent: WO2018/93569, 2018, A1. Location in patent: Page/Page column 134
[2] Journal of the American Chemical Society, 1953, vol. 75, p. 4048,4050

2-(1H-PYRAZOL-4-YL)-ETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(1H-PYRAZOL-4-YL)-ETHANOL Suppliers

Changsha Luxing Bio-Chem Technology Co., Ltd.
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0731-88827538 15873153880
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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Jia Xing Isenchem Co.,Ltd
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Shanghai Ennopharm Co., Ltd.
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Heterochem
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027-88041443 13072715837
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027-51829379
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sales@hetero-chem.com
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Suzhou Sibian Chemical Technology Co.,Ltd.
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0512-65617459 18915409046
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0512-65617459
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sales@sibian-chem.com
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China
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View Lastest Price from 2-(1H-PYRAZOL-4-YL)-ETHANOL manufacturers

Career Henan Chemical Co
Product
2-(1H-PYRAZOL-4-YL)-ETHANOL 180207-57-2
Price
US $5.50/KG
Min. Order
1KG
Purity
98%min
Supply Ability
1kg,10kg,100kg
Release date
2020-01-09