Methyl coumalate
- Product Name
- Methyl coumalate
- CAS No.
- 6018-41-3
- Chemical Name
- Methyl coumalate
- Synonyms
- METHYL 2-OXO-2H-PYRAN-5-CARBOXYLATE;Coumalic acid methyl ester;Methyl coumaric acid;METHYL COUMALATE;TIMTEC-BB SBB000117;Methyl coumalate 98%;Methyl Coumalate >5-(Carbomethoxy)-2-pyrone;Methyl 2-pyrone-5-carboxylate;METHYL PYR-2-ONE-5-CARBOXYLATE
- CBNumber
- CB8755382
- Molecular Formula
- C7H6O4
- Formula Weight
- 154.12
- MOL File
- 6018-41-3.mol
Methyl coumalate Property
- Melting point:
- 65-67 °C (lit.)
- Boiling point:
- 178-180 °C/60 mmHg (lit.)
- Density
- 1.1993 (rough estimate)
- refractive index
- 1.4300 (estimate)
- Flash point:
- 178-180°C/60mm
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Freely soluble in dichloromethane.
- form
- powder to crystal
- color
- White to Orange to Green
- Merck
- 14,2557
- BRN
- 126301
- LogP
- -0.660 (est)
- CAS DataBase Reference
- 6018-41-3(CAS DataBase Reference)
- NIST Chemistry Reference
- 2H-Pyran-5-carboxylic acid, 2-oxo-, methyl ester(6018-41-3)
Safety
- WGK Germany
- 3
- HS Code
- 2932209090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P308+P313IF exposed or concerned: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P403Store in a well-ventilated place.
N-Bromosuccinimide Price
- Product number
- 261432
- Product name
- Methyl coumalate
- Purity
- 98%
- Packaging
- 10g
- Price
- $441
- Updated
- 2024/03/01
- Product number
- C1734
- Product name
- Methyl Coumalate
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $85
- Updated
- 2024/03/01
- Product number
- C1734
- Product name
- Methyl Coumalate
- Purity
- >96.0%(GC)
- Packaging
- 25g
- Price
- $278
- Updated
- 2024/03/01
- Product number
- B25330
- Product name
- Methyl coumalate, 98%
- Packaging
- 2g
- Price
- $47.65
- Updated
- 2024/03/01
- Product number
- B25330
- Product name
- Methyl coumalate, 98%
- Packaging
- 10g
- Price
- $165.65
- Updated
- 2024/03/01
Methyl coumalate Chemical Properties,Usage,Production
Uses
α, β-Unsaturated ketone Methyl Coumalate showed cytotoxicity against human normal gingival fibroblast cells and oral squamous cell carcinoma cell line-2.
Uses
Methyl coumalate is a 2-pyrone and acts as dienophile in Diels-Alder reaction. It reacts with 1,3-butadienes at 100°C to yield tetrahydrocoumarins and 4-methoxycarbonyltricyclo[3.2.1.02,7]octenes. It also reacts with cyclohexadiene to afford tetrahydronaphthalene-2-carboxylate. It undergoes Diels-Alder reaction with unactivated alkenes to afford para-substituted adducts. It has been used as reagent in phosphine-catalyzed [4+3] annulation of modified allylic carbonates. It was also used in the preparation of 7-carboxyquinolizinium derivatives.
Uses
Methyl coumalate has been used as reagent in phosphine-catalyzed [4+3] annulation of modified allylic carbonates. It was also used in the preparation of 7-carboxyquinolizinium derivatives.
General Description
Methyl coumalate is a 2-pyrone and acts as dienophile in Diels-Alder reaction. It reacts with 1,3-butadienes at 100°C to yield tetrahydrocoumarins and 4-methoxycarbonyltricyclo[3.2.1.02,7]octenes. It also reacts with cyclohexadiene to afford tetrahydronaphthalene-2-carboxylate. It undergoes Diels-Alder reaction with unactivated alkenes to afford para-substituted adducts.
Methyl coumalate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl coumalate manufacturers
- Product
- Methyl coumaric acid 6018-41-3
- Price
- US $48.00-40.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200tons
- Release date
- 2021-06-09
- Product
- methyl 2-oxo-2H-pyran-5-carboxylate 6018-41-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2020-01-03
- Product
- Methyl coumalate 6018-41-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10