NEOMYCIN B
- Product Name
- NEOMYCIN B
- CAS No.
- 119-04-0
- Chemical Name
- NEOMYCIN B
- Synonyms
- actilin;actiline;framygen;Framidal;Framycin;enterfram;Francetin;Fraquinol;framycetin;NEOMYCIN B
- CBNumber
- CB8761428
- Molecular Formula
- C23H46N6O13
- Formula Weight
- 614.64
- MOL File
- 119-04-0.mol
NEOMYCIN B Property
- Melting point:
- >194°C (dec.)
- Boiling point:
- 658.4°C (rough estimate)
- Density
- 1.3548 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- 2-8°C
- solubility
- Aqueous Acid (Slightly), Water (Slightly)
- form
- liquid
- pka
- 12.93±0.70(Predicted)
- color
- clear
- Merck
- 13,6482
- Stability:
- Hygroscopic
Safety
- Hazard Codes
- Xn
- Risk Statements
- 42/43-63-36/37/38
- Safety Statements
- 26-36/37/39-45-36/37-23
- WGK Germany
- 2
- F
- 8
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- N1142
- Product name
- Neomycin solution
- Purity
- with 10 mg/mL neomycin in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture
- Packaging
- 20ml
- Price
- $17.3
- Updated
- 2024/03/01
- Product number
- 285570
- Product name
- Neomycin solution
- Packaging
- 20g
- Price
- $410
- Updated
- 2021/12/16
- Product number
- 165605
- Product name
- Neomycin B
- Packaging
- 1mg
- Price
- $496
- Updated
- 2021/12/16
- Product number
- N389983
- Product name
- NeomycinB
- Packaging
- 10mg
- Price
- $1695
- Updated
- 2021/12/16
- Product number
- 60608
- Product name
- NeomycinB
- Packaging
- 1mg
- Price
- $675
- Updated
- 2021/12/16
NEOMYCIN B Chemical Properties,Usage,Production
Uses
Neomycin C is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
Definition
ChEBI: A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B.
General Description
Chemical structure: aminoglycoside
Biochem/physiol Actions
Neomycin is an aminoglycoside antibiotic, produced by Streptomyces containing a minimum of 85% neomycin B. It acts as a selection agent for prokaryotic cells transformed using the neo selectable marker gene. Neomycin trisulfate is used to study the cytototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts and extraction of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins. This product is recommended for use in cell culture applications at 5 mL/L.Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria
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