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NEOMYCIN B

Product Name
NEOMYCIN B
CAS No.
119-04-0
Chemical Name
NEOMYCIN B
Synonyms
actilin;actiline;framygen;Framidal;Framycin;enterfram;Francetin;Fraquinol;framycetin;NEOMYCIN B
CBNumber
CB8761428
Molecular Formula
C23H46N6O13
Formula Weight
614.64
MOL File
119-04-0.mol
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NEOMYCIN B Property

Melting point:
>194°C (dec.)
Boiling point:
658.4°C (rough estimate)
Density 
1.3548 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
2-8°C
solubility 
Aqueous Acid (Slightly), Water (Slightly)
form 
liquid
pka
12.93±0.70(Predicted)
color 
clear
Merck 
13,6482
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xn
Risk Statements 
42/43-63-36/37/38
Safety Statements 
26-36/37/39-45-36/37-23
WGK Germany 
2
F 
8
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N1142
Product name
Neomycin solution
Purity
with 10 mg/mL neomycin in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture
Packaging
20ml
Price
$17.3
Updated
2024/03/01
TRC
Product number
N389983
Product name
NeomycinB
Packaging
10mg
Price
$1695
Updated
2021/12/16
Usbiological
Product number
285570
Product name
Neomycin solution
Packaging
20g
Price
$410
Updated
2021/12/16
Usbiological
Product number
165605
Product name
Neomycin B
Packaging
1mg
Price
$496
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
60608
Product name
NeomycinB
Packaging
1mg
Price
$675
Updated
2021/12/16
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NEOMYCIN B Chemical Properties,Usage,Production

Uses

Neomycin C is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.

Definition

ChEBI: A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B.

General Description

Chemical structure: aminoglycoside

Biochem/physiol Actions

Neomycin is an aminoglycoside antibiotic, produced by Streptomyces containing a minimum of 85% neomycin B. It acts as a selection agent for prokaryotic cells transformed using the neo selectable marker gene. Neomycin trisulfate is used to study the cytototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts and extraction of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins. This product is recommended for use in cell culture applications at 5 mL/L.Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria

NEOMYCIN B Preparation Products And Raw materials

Raw materials

Preparation Products

Neomycin
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NEOMYCIN B Suppliers

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119-04-0, NEOMYCIN BRelated Search:

Neomycin sulfate NEOMYCIN B bacitracin-neomycin-polymyxinointmen Neomycin Neomycin sulphate soluble powder NEOMYCIN E ANTI-NEOMYCIN PHOSPHOTRANSFERASE II Neomycin B sulfate neomycin B sulphate NEOMYCIN SULPHATE FOR MICROBIOLOGICAL ASSAY NEOMYCIN SULPHATE ORAL PENICILLIN STREPTOMYCIN NEOMYCIN "G" IRRADIATED TISSUE CULTURE GRADE {NEOMYCIN SULFATE N/H PENICILLIN-STREPTOMYCIN-NEOMYCIN GAMMA-& Neomycin, hydrochloride 100 G NEOMYCIN.SULFATERESEARCH GRADE ANTI-NEOMYCIN (INCLUDES BSA CONJUGATE),ANTI-NEOMYCIN NEOMYCIN B TRISULFATE SALT SESQUIHYDRATE Framycetin

  • Neomycin solution
  • neomycine standard solution
  • D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1?3)-O-.beta.-D-ribofuranosyl-(1?5)-O-2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1?4)-2-deoxy-
  • NEOMYCIN STANDARD
  • NEOMYCIN B
  • actilin
  • actiline
  • antibiotique
  • enterfram
  • framycetin
  • framygen
  • soframycin
  • soframycine
  • FRADIOMYCIN B; NEOMYCIN B
  • Neomycin B Hexaacetate
  • 4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]-2-deoxy-D-streptamine
  • (2R,3S,4R,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-6-(aminomethyl)-3-azanyl-4,5-dihydroxy-oxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-4,6-bis(azanyl)-3-hydroxy-cyclohexyl]oxy-5-azanyl-oxane-3,4-diol
  • (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
  • (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-3-hydroxy-cyclohexoxy]tetrahydropyran-3,4-diol
  • Antibiotic 10676
  • Antibiotique EF 185
  • Dekamycin III
  • Framidal
  • Framycin
  • Francetin
  • Fraquinol
  • Leo Red Dry Cow
  • D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-
  • NEOMYCIN B USP/EP/BP
  • 119-04-0
  • 1190-04-0
  • BioChemical
  • Antibiotics A to Z
  • Antibiotics
  • Antibiotics N-S
  • Mechanism of Action
  • N
  • L - ZAlphabetic
  • NA - NIMore...Close...
  • AminoglycosidesAntibiotics
  • Antibacterial
  • Antibiotics
  • Antibiotics A to
  • Antibiotics by Application
  • Antibiotics N-SAntibiotics
  • Antineoplastic and Immunosuppressive AntibioticsAntibiotics
  • Chemical Structure Class
  • Genetic Marker SelectionAntibiotics
  • Interferes with Protein SynthesisSpectrum of Activity