ChemicalBook > CAS DataBase List > NEOMYCIN B

NEOMYCIN B

Product Name: NEOMYCIN B
CAS No.: 119-04-0
Chemical Name: NEOMYCIN B
Synonyms: actilin;actiline;framygen;Framidal;Framycin;enterfram;Francetin;Fraquinol;framycetin;NEOMYCIN B
CBNumber: CB8761428
Molecular Formula: C23H46N6O13
Formula Weight: 614.64
MOL File: 119-04-0.mol

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NEOMYCIN B Property

Melting point:: >194°C (dec.)
Boiling point:: 658.4°C (rough estimate)
Density: 1.3548 (rough estimate)
refractive index: 1.6000 (estimate)
storage temp.: 2-8°C
solubility: Aqueous Acid (Slightly), Water (Slightly)
form: liquid
pka: 12.93±0.70(Predicted)
color: clear
biological source: Streptomyces fradiae
Merck: 13,6482
Stability:: Hygroscopic

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Safety

Hazard Codes: Xn
Risk Statements: 42/43-63-36/37/38
Safety Statements: 26-36/37/39-45-36/37-23
WGK Germany: 2
F: 8

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N1142
Product name: Neomycin solution
Purity: with 10 mg/mL neomycin in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture
Packaging: 20ml
Price: $18.6
Updated: 2025/07/31

Usbiological

Product number: 285570
Product name: Neomycin solution
Packaging: 20g
Price: $410
Updated: 2021/12/16

Usbiological

Product number: 165605
Product name: Neomycin B
Packaging: 1mg
Price: $496
Updated: 2021/12/16

TRC

Product number: N389983
Product name: NeomycinB
Packaging: 10mg
Price: $1695
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 60608
Product name: NeomycinB
Packaging: 1mg
Price: $675
Updated: 2021/12/16

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NEOMYCIN B Chemical Properties,Usage,Production

Uses

Neomycin C is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.

Definition

ChEBI: A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B.

General Description

Chemical structure: aminoglycoside

Biochem/physiol Actions

Neomycin is an aminoglycoside antibiotic, produced by Streptomyces containing a minimum of 85% neomycin B. It acts as a selection agent for prokaryotic cells transformed using the neo selectable marker gene. Neomycin trisulfate is used to study the cytototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts and extraction of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins. This product is recommended for use in cell culture applications at 5 mL/L.Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria

IC 50

Aminoglycoside

NEOMYCIN B Preparation Products And Raw materials

Raw materials

Preparation Products

Neomycin

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119-04-0, NEOMYCIN BRelated Search:

Neomycin sulfate NEOMYCIN B bacitracin-neomycin-polymyxinointmen Neomycin Neomycin sulphate soluble powder NEOMYCIN E ANTI-NEOMYCIN PHOSPHOTRANSFERASE II Neomycin B sulfate neomycin B sulphate NEOMYCIN SULPHATE FOR MICROBIOLOGICAL ASSAY NEOMYCIN SULPHATE ORAL PENICILLIN STREPTOMYCIN NEOMYCIN "G" IRRADIATED TISSUE CULTURE GRADE {NEOMYCIN SULFATE N/H PENICILLIN-STREPTOMYCIN-NEOMYCIN GAMMA-& Neomycin, hydrochloride 100 G NEOMYCIN.SULFATERESEARCH GRADE ANTI-NEOMYCIN (INCLUDES BSA CONJUGATE),ANTI-NEOMYCIN NEOMYCIN B TRISULFATE SALT SESQUIHYDRATE Framycetin

Neomycin solution

neomycine standard solution

D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1?3)-O-.beta.-D-ribofuranosyl-(1?5)-O-2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1?4)-2-deoxy-

NEOMYCIN STANDARD

NEOMYCIN B

actilin

actiline

antibiotique

enterfram

framycetin

framygen

soframycin

soframycine

FRADIOMYCIN B; NEOMYCIN B

Neomycin B Hexaacetate

4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]-2-deoxy-D-streptamine

(2R,3S,4R,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-6-(aminomethyl)-3-azanyl-4,5-dihydroxy-oxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-4,6-bis(azanyl)-3-hydroxy-cyclohexyl]oxy-5-azanyl-oxane-3,4-diol

(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol

(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-3-hydroxy-cyclohexoxy]tetrahydropyran-3,4-diol

Antibiotic 10676

Antibiotique EF 185

Dekamycin III

Framidal

Framycin

Francetin

Fraquinol

Leo Red Dry Cow

D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-

NEOMYCIN B USP/EP/BP

Neomycin B/Neomycin B Acetate

119-04-0

1190-04-0

BioChemical

Antibiotics A to Z

Antibiotics

Antibiotics N-S

Mechanism of Action

L - ZAlphabetic

NA - NIMore...Close...

AminoglycosidesAntibiotics

Antibacterial

Antibiotics

Antibiotics A to

Antibiotics by Application

Antibiotics N-SAntibiotics

Antineoplastic and Immunosuppressive AntibioticsAntibiotics

Chemical Structure Class

Genetic Marker SelectionAntibiotics

Interferes with Protein SynthesisSpectrum of Activity