Vanadinocene Dichloride
- Product Name
- Vanadinocene Dichloride
- CAS No.
- 12083-48-6
- Chemical Name
- Vanadinocene Dichloride
- Synonyms
- dichlorovanadocene;VANADOCENE CHLORIDE;VANADOCENE DICHLORIDE;VANADINOCENE DICHLORIDE;Cyclopentane Dichlorovanadium;Dicyclopentadienyldichlorovanadium;Dicyclopentadienevanadium dichloride;Dichlorobis(cyclopentadienyl)vanadium;dichlorodi-pi-cyclopentadienyl-vanadiu;dichlorodi-pi-cyclopentadienylvanadium
- CBNumber
- CB8763194
- Molecular Formula
- C10H10Cl2V10*
- Formula Weight
- 252.03
- MOL File
- 12083-48-6.mol
Vanadinocene Dichloride Property
- Melting point:
- 182-194 °C (dec.)(lit.)
- Density
- 1,6 g/cm3
- storage temp.
- 2-8°C
- solubility
- soluble in H2O, chloroform, ethanol
- form
- crystal
- Specific Gravity
- 1.6
- color
- green
- Water Solubility
- Reacts with water
- Sensitive
- Air & Moisture Sensitive
- Exposure limits
- NIOSH: Ceiling 0.05 mg/m3
- CAS DataBase Reference
- 12083-48-6(CAS DataBase Reference)
- EPA Substance Registry System
- Vanadocene dichloride (12083-48-6)
Safety
- Hazard Codes
- T
- Risk Statements
- 25-36/37/38
- Safety Statements
- 26-28-36/37/39-45
- RIDADR
- UN 3285 6.1/PG 3
- WGK Germany
- 3
- RTECS
- YW1580000
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29310099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- V0090
- Product name
- Vanadinocene Dichloride
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $198
- Updated
- 2023/06/20
- Product number
- 039588
- Product name
- Bis(cyclopentadienyl)vanadium dichloride, 95%
- Packaging
- 1g
- Price
- $61.5
- Updated
- 2021/12/16
- Product number
- 23-0200
- Product name
- Bis(cyclopentadienyl)vanadium dichloride (Vanadocene dichloride), 95%
- Packaging
- 1g
- Price
- $97
- Updated
- 2024/03/01
- Product number
- 23-0200
- Product name
- Bis(cyclopentadienyl)vanadium dichloride (Vanadocene dichloride), 95%
- Packaging
- 5g
- Price
- $379
- Updated
- 2024/03/01
- Product number
- 23-0200
- Product name
- Bis(cyclopentadienyl)vanadium dichloride (Vanadocene dichloride), 95%
- Packaging
- 25g
- Price
- $1499
- Updated
- 2024/03/01
Vanadinocene Dichloride Chemical Properties,Usage,Production
Chemical Properties
dark green crystalline powder
Uses
Vanadocene dichloride is used like other metallocenes as a catalyst, ultraviolet absorber, reducing agent, free radical scavenger, antiknock agent in gasoline, and as a developmental anticancer drug.
Uses
Bis(cyclopentadienyl)vanadium(IV) dichloride is a catalyst for solvent free, room temperature preparation of vicinal amino alcohols as fungistatic agents, catalyst fot oligomerization reactions via the Aufbau propagation reaction and as a catalyst for aqueous polymerization reactions using oxygen as a co catalyst. It is used as a catalyst for dl-selective pinacol-type coupling reactions, as an affecter of crystal growth of calcium carbonate and and as an inhibitor of human topoisomerase II enzyme with antitumor activity.
General Description
Pale green crystals or green powder.
Air & Water Reactions
Extremely sensitive to exposure to air. Also extremely sensitive to moisture; decomposes in water
Reactivity Profile
Organometallics, such as BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE, are reactive with many other groups. Incompatible with acids and bases. Organometallics are good reducing agents and therefore incompatible with oxidizing agents. Often reactive with water to generate toxic or flammable gases. Organometallics containing halogens (fluorine, chlorine, bromine, iodine) bonded to the metal typically with generate gaseous hydrohalic acids (HF, HCl, HBr, HI) with water.
Fire Hazard
Flash point data for BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE are not available. BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE is probably combustible.
Pharmaceutical Applications
Vanadocene dichloride [( η5-C5H5)2VCl2, dichloro bis(η5-cyclopentadienyl)vanadium(IV)] is structurally very similar to Cp2TiCl2. It also consists of a metal centre with an oxidation number of +IV, in this case vanadium, and two Cp and two chloride ligands. Vanadocene dichloride is a 17-electron complex containing an unpaired electron and is therefore paramagnetic .
Vanadocene dichloride has found application as a catalyst for polymerisation reactions, but was also intensively studied as an anticancer agent in parallel to Cp2TiCl2 because of their structural similarities. Vanadocene dichloride has proven to be even more effective than its titanium analogue as an antiproliferative agent against both animal and human cell lines in preclinical testing. The main problems are the difficult characterisation of the active vanadium compounds and their fast hydrolysis.
Pharmaceutical Applications
Vanadocene dichloride [(η5-C5H5)2VCl2, dichloro bis(η5-cyclopentadienyl)vanadium(IV)] is structurally very similar to Cp2TiCl2. It also consists of a metal centre with an oxidation number of +IV, in this case vanadium, and two Cp and two chloride ligands. Vanadocene dichloride is a 17-electron complex containing an unpaired electron and is therefore paramagnetic. Vanadocene dichloride has found application as a catalyst for polymerisation reactions, but was also intensively studied as an anticancer agent in parallel to Cp2TiCl2 because of their structural similarities. Vanadocene dichloride has proven to be even more effective than its titanium analogue as an antiproliferative agent against both animal and human cell lines in preclinical testing.
Vanadinocene Dichloride Preparation Products And Raw materials
Raw materials
Preparation Products
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