(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

Product Name
(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
CAS No.
104422-04-0
Chemical Name
(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
Synonyms
sk&f77434;SKF 77434 HYDROBROMIDE;(+/-)-SKF-77434 HYDROBROMIDE;(+/-)-N-ALLYL-SKF-38393 HYDROBROMIDE;(+/-)-SKF-38393, N-ALLYL-, HYDROBROMIDE;(+)-SKF-38393, N-ALLYL-, HYDROBROMIDE D1 DOPAMINE AGONIST;N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol;2,3,4,5-Tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol;1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-;2,3,4,5-TETRAHYDRO-1-PHENYL-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE
CBNumber
CB8780199
Molecular Formula
C19H21NO2
Formula Weight
295.38
MOL File
104422-04-0.mol
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(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Property

storage temp. 
2-8°C
solubility 
ethanol: 3.2 mg/mL
form 
solid
color 
white or off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1662
Product name
SKF77434hydrobromide
Purity
≥99%(HPLC)
Packaging
10
Price
$90
Updated
2021/12/16
Tocris
Product number
1662
Product name
SKF77434hydrobromide
Purity
≥99%(HPLC)
Packaging
50
Price
$376
Updated
2021/12/16
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(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties,Usage,Production

Uses

N-Allyl-(+/-)-SKF-38393 hydrobromide is a selective dopamine D1-like receptor partial agonist.

Definition

ChEBI: A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, an allyl substituent at position 3 and two hydroxy substituents at positions 7 and 8. Selective dopamine D1-like receptor partial agonist (IC50 values are 19 7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.

Biological Activity

Selective dopamine D 1 -like receptor partial agonist (IC 50 values are 19.7 and 2425 nM for binding to D 1 -like and D 2 -like receptors respectively). Centrally active following systemic administration in vivo .

(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Suppliers

SIGMA-RBI
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Country
Switzerland
ProdList
6896
Advantage
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104422-04-0, (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDERelated Search:


  • sk&f77434
  • (+/-)-SKF-38393, N-ALLYL-, HYDROBROMIDE
  • (+/-)-SKF-77434 HYDROBROMIDE
  • SKF 77434 HYDROBROMIDE
  • (+/-)-N-ALLYL-SKF-38393 HYDROBROMIDE
  • 2,3,4,5-TETRAHYDRO-1-PHENYL-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE
  • (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
  • (+)-SKF-38393, N-ALLYL-, HYDROBROMIDE D1 DOPAMINE AGONIST
  • 2,3,4,5-Tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol
  • N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol
  • 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-
  • 104422-04-0
  • C19H21NO2HBr