4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID

Product Name: 4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID
CAS No.: 152529-79-8
Chemical Name: 4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID
Synonyms: 4-(2,6-Dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl)benzenesulfonic acid;4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid;4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID;BENZENESULFONIC ACID,4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-;Benzenesulfonic acid, 4-(2,3,6,9-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-
CBNumber: CB8784470
Molecular Formula: C14H14N4O5S
Formula Weight: 350.35
MOL File: 152529-79-8.mol

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4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID Property

Melting point:: >300 °C
Density: 1.522±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C, protect from light
solubility: Soluble to 100 mM in DMSO and to 20 mM in water with gentle warming
form: Powder
pka: -1.59±0.50(Predicted)
color: Off-white to light brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B6922
Product name: PSB1115
Packaging: 5mg
Price: $82
Updated: 2021/12/16

ApexBio Technology

Product number: B6922
Product name: PSB1115
Packaging: 10mg
Price: $147
Updated: 2021/12/16

ApexBio Technology

Product number: B6922
Product name: PSB1115
Packaging: 25mg
Price: $327
Updated: 2021/12/16

Chemenu

Product number: CM266074
Product name: 4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonicacid
Purity: 95%
Packaging: 1g
Price: $790
Updated: 2021/12/16

Crysdot

Product number: CD11249380
Product name: 4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonicacid
Purity: 95+%
Packaging: 1g
Price: $845
Updated: 2021/12/16

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4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID Chemical Properties,Usage,Production

Uses

PSB-1115 is a selective A2B Adenosine Receptor antagonist. PSB-1115 inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh)[1].

Definition

ChEBI: 4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonic acid is an oxopurine.

in vivo

PSB-1115 (0.5 mg/kg; i.p.; single dose, injected 20 minutes before inhalation) antagonizes the inhibitory effect of the non-selective adenosine receptor agonist NECA (HY-103173) on mucociliary clearance in mice^[2].

IC 50

A2BR

storage

Store at RT

References

[1] Michael S, et al. Adenosine A(2A) agonist and A(2B) antagonist mediate an inhibition of inflammation-induced contractile disturbance of a rat gastrointestinal preparation. Purinergic Signal. 2010 Mar;6(1):117-24. DOI:10.1007/s11302-009-9174-y

4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID Suppliers

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152529-79-8, 4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACIDRelated Search:

Benzenesulfonic acid 4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID POTASSIUM SALT PSB 1115 POTASSIUM SALT 4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID 2-PHENYL-1H-IMIDAZOL-4-AMINE 1,3-DIPROPYL-8-P-SULFOPHENYLXANTHINE MONO-P-TOLUENESULFONATE UREA

4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID

4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid

BENZENESULFONIC ACID,4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-

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4-(2,6-Dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl)benzenesulfonic acid

152529-79-8

Adenosine receptor