GSK-3484862

Product Name: GSK-3484862
CAS No.: 2170136-65-7
Chemical Name: GSK-3484862
Synonyms: GSK-3484862;GSK-3484862 (GSKMI-714);GSK-3484862, 10 mM in DMSO;Benzeneacetamide, α-[[3,5-dicyano-6-(dimethylamino)-4-ethyl-2-pyridinyl]thio]-, (αR)-;inhibit,methyltransferase1,5-Azacytidine,Inhibitor,hypomethylation,Dnmt1,therapies,GSK3484862,DNA MTases,DNA,GSK-3484862,epigenetic,DNA Methyltransferase,DNMTs,GSK 3484862
CBNumber: CB88054418
Molecular Formula: C19H19N5OS
Formula Weight: 365.45
MOL File: 2170136-65-7.mol

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GSK-3484862 Property

Boiling point:: 620.5±55.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
solubility: DMSO:20.83(Max Conc. mg/mL);57.0(Max Conc. mM)
pka: 14.62±0.50(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0109599
Product name: GSK-3484862
Purity: 99.94%
Packaging: 10mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0109599
Product name: GSK-3484862
Purity: 99.94%
Packaging: 50mg
Price: $650
Updated: 2021/12/16

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GSK-3484862 Chemical Properties,Usage,Production

Description

GSK-3484862 is a non-covalent inhibitor for Dnmt1. GSK-3484862 induces DNA hypomethylation to against cancer.

in vitro

In total, methylation mapping supports the conclusion that GSK-3484862 treatment produces a drop in DNA methylation consistent with selective and near complete inhibition of DNMT1._x000D_ _x000D_ Reference: Epigenetics Chromatin. 2021 Dec 15;14(1):56. https://pubmed.ncbi.nlm.nih.gov/34906184/

target

GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer.

GSK-3484862 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK-3484862 Suppliers

China 19 United States 3 Global 22

Chengdu PEIP Pharmaceutical Technology Co., LTD.

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Beijing Biocreative Technology Co., Ltd.

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2170136-65-7, GSK-3484862Related Search:

GSK-3484862

inhibit,methyltransferase1,5-Azacytidine,Inhibitor,hypomethylation,Dnmt1,therapies,GSK3484862,DNA MTases,DNA,GSK-3484862,epigenetic,DNA Methyltransferase,DNMTs,GSK 3484862

Benzeneacetamide, α-[[3,5-dicyano-6-(dimethylamino)-4-ethyl-2-pyridinyl]thio]-, (αR)-

GSK-3484862 (GSKMI-714)

GSK-3484862, 10 mM in DMSO

2170136-65-7