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GSK-3484862

Product Name
GSK-3484862
CAS No.
2170136-65-7
Chemical Name
GSK-3484862
Synonyms
GSK-3484862;GSK-3484862 (GSKMI-714);GSK-3484862, 10 mM in DMSO;Benzeneacetamide, α-[[3,5-dicyano-6-(dimethylamino)-4-ethyl-2-pyridinyl]thio]-, (αR)-;inhibit,methyltransferase1,5-Azacytidine,Inhibitor,hypomethylation,Dnmt1,therapies,GSK3484862,DNA MTases,DNA,GSK-3484862,epigenetic,DNA Methyltransferase,DNMTs,GSK 3484862
CBNumber
CB88054418
Molecular Formula
C19H19N5OS
Formula Weight
365.45
MOL File
2170136-65-7.mol
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GSK-3484862 Property

Boiling point:
620.5±55.0 °C(Predicted)
Density 
1.30±0.1 g/cm3(Predicted)
solubility 
DMSO:20.83(Max Conc. mg/mL);57.0(Max Conc. mM)
pka
14.62±0.50(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0109599
Product name
GSK-3484862
Purity
99.94%
Packaging
10mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0109599
Product name
GSK-3484862
Purity
99.94%
Packaging
50mg
Price
$650
Updated
2021/12/16
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GSK-3484862 Chemical Properties,Usage,Production

Description

GSK-3484862 is a non-covalent inhibitor for Dnmt1. GSK-3484862 induces DNA hypomethylation to against cancer.

in vitro

In total, methylation mapping supports the conclusion that GSK-3484862 treatment produces a drop in DNA methylation consistent with selective and near complete inhibition of DNMT1._x000D_ _x000D_ Reference: Epigenetics Chromatin. 2021 Dec 15;14(1):56. https://pubmed.ncbi.nlm.nih.gov/34906184/

target

GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer.

GSK-3484862 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK-3484862 Suppliers

China 19 United States 3 Global 22
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58

2170136-65-7, GSK-3484862Related Search:


  • GSK-3484862
  • inhibit,methyltransferase1,5-Azacytidine,Inhibitor,hypomethylation,Dnmt1,therapies,GSK3484862,DNA MTases,DNA,GSK-3484862,epigenetic,DNA Methyltransferase,DNMTs,GSK 3484862
  • Benzeneacetamide, α-[[3,5-dicyano-6-(dimethylamino)-4-ethyl-2-pyridinyl]thio]-, (αR)-
  • GSK-3484862 (GSKMI-714)
  • GSK-3484862, 10 mM in DMSO
  • 2170136-65-7