Boc-C1-PEG3-C4-OH

Product Name: Boc-C1-PEG3-C4-OH
CAS No.: 2376724-97-7
Chemical Name: Boc-C1-PEG3-C4-OH
Synonyms: Boc-C1-PEG3-C4-OH;Acetic acid, 2-[2-[2-[(6-hydroxyhexyl)oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber: CB88054685
Molecular Formula: C16H32O6
Formula Weight: 320.42
MOL File: 2376724-97-7.mol

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Boc-C1-PEG3-C4-OH Property

Boiling point:: 409.3±35.0 °C(Predicted)
Density: 1.024±0.06 g/cm3(Predicted)
solubility: Soluble in DMSO
form: Liquid
pka: 15.18±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Boc-C1-PEG3-C4-OH Chemical Properties,Usage,Production

Biological Activity

Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the Alkyl/ether composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

Boc-C1-PEG3-C4-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-C1-PEG3-C4-OH Suppliers

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2376724-97-7, Boc-C1-PEG3-C4-OHRelated Search:

Boc-C1-PEG3-C4-OH

Acetic acid, 2-[2-[2-[(6-hydroxyhexyl)oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester

2376724-97-7