Mal-PEG8-alcohol

Product Name: Mal-PEG8-alcohol
CAS No.: 2353409-63-7
Chemical Name: Mal-PEG8-alcohol
Synonyms: Mal-PEG8-alcohol;1-(23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricosyl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione,1-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)-;1-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosan-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
CBNumber: CB88054751
Molecular Formula: C20H35NO10
Formula Weight: 449.49
MOL File: 2353409-63-7.mol

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Mal-PEG8-alcohol Property

Boiling point:: 559.0±50.0 °C(Predicted)
Density: 1.192±0.06 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: 14.36±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24266
Product name: Mal-PEG8-alcohol
Packaging: 100mg
Price: $340
Updated: 2021/12/16

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Mal-PEG8-alcohol Chemical Properties,Usage,Production

Description

Mal-PEG8-alcohol is a PEG linker containing a maleimide group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG8-alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG8-alcohol Suppliers

China 22 United States 1 Global 23

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View Lastest Price from Mal-PEG8-alcohol manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-PEG8-OH 2353409-63-7
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-27

2353409-63-7, Mal-PEG8-alcoholRelated Search:

Mal-PEG2-alcohol 1,8-BIS-MALEIMIDOTRIETHYLENEGLYCOL Mal-PEG8-amine TFA salt Mal-PEG2-Val-Cit-amido-PAB-OH 1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione Mal-PEG2-NHS ester Mal-PEG2-acid Mal-PEG2-CH2CH2COOtBu

Mal-PEG8-alcohol

1H-Pyrrole-2,5-dione,1-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)-

1-(23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricosyl)-1H-pyrrole-2,5-dione

1-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosan-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

2353409-63-7