ChemicalBook > CAS DataBase List > (2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME

(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME

Product Name
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
CAS No.
667463-85-6
Chemical Name
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
Synonyms
CS-1611;BIO-ACETOXIME;GSK-3 INHIBITOR X;GSK3 Inhibitor IX2;BIA|||GSK-3 Inhibitor X;6-Bromoindirubin acetoxime;BIO-Acetoxime >=98% (HPLC);6-Bromoindirubin-3′-acetoxime;BIO-acetoxime(GSK-3 Inhibitor);BIO-acetoxime GSK3 Inhibitor IX2
CBNumber
CB8818870
Molecular Formula
C18H12BrN3O3
Formula Weight
398.21
MOL File
667463-85-6.mol
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(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Property

Density 
1.69±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
H2O: soluble2mg/mL (clear solution, warmed)
form 
powder
pka
9.22±0.20(Predicted)
color 
dark red to purple
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-50/53
Safety Statements 
60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0531
Product name
BIO-Acetoxime
Purity
≥98% (HPLC)
Packaging
5mg
Price
$171
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0531
Product name
BIO-Acetoxime
Purity
≥98% (HPLC)
Packaging
25mg
Price
$656
Updated
2024/03/01
Tocris
Product number
3874
Product name
BIO-acetoxime
Purity
≥98%(HPLC)
Packaging
10
Price
$308
Updated
2021/12/16
Tocris
Product number
3874
Product name
BIO-acetoxime
Purity
≥98%(HPLC)
Packaging
1
Price
$148
Updated
2021/12/16
TRC
Product number
B591760
Product name
BIO-acetoxime
Packaging
1mg
Price
$55
Updated
2021/12/16
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(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Chemical Properties,Usage,Production

Uses

BIO-Acetoxime is a potent and selective GSK-3a/b inhibitor that reduces invasiveness of gliomas and extends animal survival in intracranial glioma models. It also induces Wnt signaling and inhibits CD8+ T cell effector differentiation.

Biological Activity

Selective GSK-3 α / β inhibitor (IC 50 values are 0.01, 2.4, 4.3 and 63 μ M for GSK-3 α / β , CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation.

storage

Store at +4°C

(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Preparation Products And Raw materials

Raw materials

Preparation Products

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(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Suppliers

China 90 United Kingdom 2 United States 12 Global 104
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
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View Lastest Price from (2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME manufacturers

Career Henan Chemical Co
Product
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME 667463-85-6
Price
US $1.00/KG
Min. Order
1KG
Purity
95--99%
Supply Ability
1ton
Release date
2020-01-03

667463-85-6, (2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIMERelated Search:


  • (2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
  • BIO-ACETOXIME
  • GSK-3 INHIBITOR X
  • (3Z)-3-[(3E)-3-[(Acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-Indol-2-one
  • 6-Bromoindirubin acetoxime
  • 6-Bromoindirubin-3′-acetoxime
  • GSK3 Inhibitor IX2
  • BIO-acetoxime(GSK-3 Inhibitor)
  • (2Z,3E)-3-(Acetoxyimino)-6'-bromo-[2,3'-biindolinylidene]-2'-one
  • BIO-acetoxime GSK3 Inhibitor IX2
  • CS-1611
  • GSK3 INHIBITOR X6-BROMOINDIRUBIN-3'-ACETOXIME
  • BIO-acetoxime (GSK-3 Inhibitor X)
  • 2H-Indol-2-one, 3-[(3E)-3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-, (3Z)-
  • BIO-Acetoxime >=98% (HPLC)
  • BIA|||GSK-3 Inhibitor X
  • 667463-85-6
  • Other enzyme inhibitors and activators