1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
- Product Name
- 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
- CAS No.
- 2154342-25-1
- Chemical Name
- 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
- Synonyms
- Poma-C1-Alkyne;Pomalidomide-propargyl;Thalidomide-4-NH-propargyl;2-(2,6-Dioxo-3-piperidyl)-4-(2-propynylamino)isoindoline-1,3-dione;2-(2,6-Dioxopiperidin-3-yl)-4-(prop-2-yn-1-ylamino)isoindoline-1,3-dione;2-(2,6-Dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
- CBNumber
- CB88374754
- Molecular Formula
- C16H13N3O4
- Formula Weight
- 311.29
- MOL File
- 2154342-25-1.mol
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Property
- Boiling point:
- 610.9±55.0 °C(Predicted)
- Density
- 1.496±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light, stored under nitrogen
- pka
- 10.73±0.40(Predicted)
- form
- Solid
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Chemical Properties,Usage,Production
Uses
Pomalidomide-propargyl contains an E3 ligand and a terminal alkyl group ready for click conjugation. Pomalidomide-propargyl is ready for conjugation to target proteins for PROTAC.
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Suppliers
- Tel
- 021-50460086-9 15921403865
- Fax
- +86-21-50462321
- han_yajun@dctc.daicel.com
- Country
- China
- ProdList
- 7440
- Advantage
- 65
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 9550
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28772
- Advantage
- 58
- Tel
- 021-61469567 13482353728
- Fax
- 021-61161605
- sales@fdc-chemical.com
- Country
- China
- ProdList
- 9964
- Advantage
- 58
- Tel
- 400-6387771-6039 18920764717
- sales@heowns.com
- Country
- China
- ProdList
- 24418
- Advantage
- 60
- Tel
- 0512-69561983 13914027025
- Fax
- 0512-69561982
- zhang_q@medinoah.com
- Country
- China
- ProdList
- 3893
- Advantage
- 58
- Tel
- 13504435624
- 1927928688@qq.com
- Country
- China
- ProdList
- 1636
- Advantage
- 58
- Tel
- 025-86755008 17751752005
- Fax
- 025-86755228
- hszhang@bestfluorodrug.com
- Country
- China
- ProdList
- 2358
- Advantage
- 58
- Tel
- nanfengpharma@126.co 18616377689
- nanfengpharma@126.com
- Country
- China
- ProdList
- 20009
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 39807
- Advantage
- 58