Thailanstatin B

Product Name: Thailanstatin B
CAS No.: 1426953-23-2
Chemical Name: Thailanstatin B
Synonyms: Thailanstatin B;2-[(2S,4S,5R,6R)-6-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[(2Z,4S)-4-(acetyloxy)pent-2-enamido]-3,6-dimethyloxan-2-yl]-3-methylpenta-1,3-dien-1-yl]-4-(chloromethyl)-4,5-dihydroxyoxan-2-yl]acetic acid;2H-Pyran-2-acetic acid, 6-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[[(2Z,4S)-4-(acetyloxy)-1-oxo-2-penten-1-yl]amino]tetrahydro-3,6-dimethyl-2H-pyran-2-yl]-3-methyl-1,3-pentadien-1-yl]-4-(chloromethyl)tetrahydro-4,5-dihydroxy-, (2S,4S,5R,6R)-
CBNumber: CB88394260
Molecular Formula: C28H42ClNO9
Formula Weight: 572.09
MOL File: 1426953-23-2.mol

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Thailanstatin B Property

Boiling point:: 768.1±60.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
pka: 4.38±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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Thailanstatin B Chemical Properties,Usage,Production

Uses

Thailanstatin B is a potent pre-mRNA splicing inhibitor (IC50=6.18 μM). Thailanstatin B shows antiproliferative activity[1].

References

[1] Liu X, et al. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. J Nat Prod. 2013;76(4):685-693. DOI:10.1021/np300913h

Thailanstatin B Preparation Products And Raw materials

Raw materials

Preparation Products

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Thailanstatin B Suppliers

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1426953-23-2, Thailanstatin BRelated Search:

Thailanstatin D Thailanstatin C Thailanstatin A

Thailanstatin B

2H-Pyran-2-acetic acid, 6-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[[(2Z,4S)-4-(acetyloxy)-1-oxo-2-penten-1-yl]amino]tetrahydro-3,6-dimethyl-2H-pyran-2-yl]-3-methyl-1,3-pentadien-1-yl]-4-(chloromethyl)tetrahydro-4,5-dihydroxy-, (2S,4S,5R,6R)-

2-[(2S,4S,5R,6R)-6-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[(2Z,4S)-4-(acetyloxy)pent-2-enamido]-3,6-dimethyloxan-2-yl]-3-methylpenta-1,3-dien-1-yl]-4-(chloromethyl)-4,5-dihydroxyoxan-2-yl]acetic acid

1426953-23-2

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