ChemicalBook > CAS DataBase List > 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID
3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID
- Product Name
- 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID
- CAS No.
- 227619-65-0
- Chemical Name
- 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID
- Synonyms
- HIP-B;(±)HIPB,(±) HIP B;3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID;rel-(3aR,6R,6aR)-Hexahydro-3-oxo-2H-pyrrolo[3,4-d]isoxazole-6-carboxylic acid;2H-Pyrrolo[3,4-d]isoxazole-6-carboxylic acid, hexahydro-3-oxo-, (3aR,6R,6aR)-rel-
- CBNumber
- CB8839808
- Molecular Formula
- C6H8N2O4
- Formula Weight
- 172.14
- MOL File
- 227619-65-0.mol
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3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Property
- storage temp.
- Store at +4°C
- form
- Powder
- Water Solubility
- Soluble to 20 mM in water
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N-Bromosuccinimide Price
ApexBio Technology
- Product number
- B6983
- Product name
- (±)-HIP-B
- Packaging
- 10mg
- Price
- $322
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0370816
- Product name
- 3-HYDROXY-4,5,6,6ALPHA-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.21
- Updated
- 2021/12/16
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3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Chemical Properties,Usage,Production
Uses
HIP-B is a potent, non-competitive excitatory amino acid transporter (EAAT) blocker. It can also be used as AMPA-Kainate receptor agonists.
Biological Activity
Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [ 3 H]D-aspartate release (IC 50 = 1.2 μ M) rather than [ 3 H]L-glutamate uptake (IC 50 = 16.9 μ M). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC 50 values are 35 and 45 μ M respectively).
3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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227619-65-0, 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACIDRelated Search:
CIS-3-HYDROXY-DL-PROLINE
3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID