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PAGOCLONE

Product Name
PAGOCLONE
CAS No.
133737-32-3
Chemical Name
PAGOCLONE
Synonyms
Ip 456;CI-1043;RP 59037;AGOCLONE;Rp 62955;(+)-Pagoclone;(+)-RP-59037; IP-456; RP-62955; CI-1043;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone;2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-3H-isoindol-1-one
CBNumber
CB8839954
Molecular Formula
C23H22ClN3O2
Formula Weight
407.89
MOL File
133737-32-3.mol
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PAGOCLONE Property

Boiling point:
582.1±50.0 °C(Predicted)
Density 
1.273±0.06 g/cm3(Predicted)
pka
1.62±0.30(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChIKey
HIUPRQPBWVEQJJ-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
25mg
Price
$198.75
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
50mg
Price
$265
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
100mg
Price
$360
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
250mg
Price
$475
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
500mg
Price
$650
Updated
2021/12/16
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PAGOCLONE Chemical Properties,Usage,Production

Description

Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.

Uses

Anti-anxiety agent.

Application

Pagoclone has been shown to have anti-inflammatory properties in an animal model of inflammatory bowel disease and may be useful for the treatment of this condition.

brand name

Bextra (Interneuron).

PAGOCLONE Preparation Products And Raw materials

Raw materials

Preparation Products

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PAGOCLONE Suppliers

Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Aishilun biotechnology (Shanghai) co., LTD
Tel
021-50676523 18019098996
Email
info@acelybio.com
Country
China
ProdList
3960
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9639
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Xi'an MC Biotech, Co., Ltd.
Tel
029-89275612 +8618991951683
Fax
8618991951683
Email
mcbio_sales@163.com
Country
China
ProdList
2251
Advantage
58
Shanghai Biolang Biotechnology Co., Ltd.
Tel
+86-15970428662 +86-13397199602
Fax
+8613397199602
Email
Niky@biolang.cn
Country
China
ProdList
515
Advantage
58
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View Lastest Price from PAGOCLONE manufacturers

Dorne Chemical Technology co. LTD
Product
Pagoclone 133737-32-3
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
airuikechemical co., ltd.
Product
PAGOCLONE 133737-32-3
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
20 tons
Release date
2024-04-07
Shandong Hanjiang Chemical Co., Ltd
Product
PAGOCLONE 133737-32-3
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10T
Release date
2024-01-25

133737-32-3, PAGOCLONERelated Search:


  • 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone
  • RP 59037
  • Ip 456
  • Rp 62955
  • 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one
  • (+)-RP-59037; IP-456; RP-62955; CI-1043
  • CI-1043
  • AGOCLONE
  • inhibit,GABA Receptor,γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,IP 456,RP 62955,RP62955,Pagoclone,Inhibitor
  • (+)-Pagoclone
  • 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-3H-isoindol-1-one
  • 133737-32-3
  • C23H22ClN3O2