ChemicalBook > CAS DataBase List > PAGOCLONE

PAGOCLONE

Product Name
PAGOCLONE
CAS No.
133737-32-3
Chemical Name
PAGOCLONE
Synonyms
Ip 456;CI-1043;RP 59037;AGOCLONE;Rp 62955;(+)-Pagoclone;(+)-RP-59037; IP-456; RP-62955; CI-1043;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone;2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-3H-isoindol-1-one
CBNumber
CB8839954
Molecular Formula
C23H22ClN3O2
Formula Weight
407.89
MOL File
133737-32-3.mol
More
Less

PAGOCLONE Property

Boiling point:
582.1±50.0 °C(Predicted)
Density 
1.273±0.06 g/cm3(Predicted)
pka
1.62±0.30(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChIKey
HIUPRQPBWVEQJJ-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
25mg
Price
$198.75
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
50mg
Price
$265
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
100mg
Price
$360
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
250mg
Price
$475
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
500mg
Price
$650
Updated
2021/12/16
More
Less

PAGOCLONE Chemical Properties,Usage,Production

Description

Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.

Uses

Anti-anxiety agent.

Application

Pagoclone has been shown to have anti-inflammatory properties in an animal model of inflammatory bowel disease and may be useful for the treatment of this condition.

brand name

Bextra (Interneuron).

PAGOCLONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PAGOCLONE Suppliers

Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9805
Advantage
58
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Aishilun biotechnology (Shanghai) co., LTD
Tel
021-50676523 18019098996
Email
info@acelybio.com
Country
China
ProdList
3960
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9639
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Xi'an MC Biotech, Co., Ltd.
Tel
029-89275612 +8618991951683
Fax
8618991951683
Email
mcbio_sales@163.com
Country
China
ProdList
2251
Advantage
58
Shanghai Biolang Biotechnology Co., Ltd.
Tel
+86-15970428662 +86-13397199602
Fax
+8613397199602
Email
Niky@biolang.cn
Country
China
ProdList
515
Advantage
58
ShanDong Look Chemical Co.,Ltd.
Tel
+8617653113219
Email
sales01@sdlookchemical.com
Country
China
ProdList
2737
Advantage
58
Wuhan Monad Medicine Tech Co.,LTD
Tel
02768782018 18771942761
Email
sales01@whmonad.com
Country
CHINA
ProdList
979
Advantage
58
Shanghai UCHEM Inc.
Tel
+862156762820 +86-13564624040
Email
sales@myuchem.com
Country
China
ProdList
7709
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
Hebei Runbin Biotechnology Co. LTD
Tel
13180553332
Email
2179877681@qq.com
Country
CHINA
ProdList
990
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Wuhan Topule
Tel
+86-02787215551 +86-19945035818
Fax
027-87215551
Email
2936752263@qq.com
Country
China
ProdList
8084
Advantage
58
cjbscvictory
Tel
13348960310 13348960310
Email
3003867561@qq.com
Country
China
ProdList
10524
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44457
Advantage
58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd
Tel
027-59308705 18871579363
Fax
027-59308705
Email
1248680011@qq.com
Country
China
ProdList
9949
Advantage
58
Hubei Wande Chemical Co., Ltd
Tel
027-59210159 15377098680
Fax
027-59210159
Email
1148280011@qq.com
Country
China
ProdList
9954
Advantage
58
Abmole Bioscience Inc.
Tel
021-50967598 02150967598
Email
sales@abmole.cn
Country
China
ProdList
4494
Advantage
58
Jiangxi ravel Biotechnology Co.,Ltd
Tel
18502762009
Email
721846333@qq.com
Country
China
ProdList
2449
Advantage
58
Hubei Kele Fine Chemical Co., Ltd
Tel
027-59101668 19945030958
Fax
027-59101668
Email
2881924765@qq.com
Country
China
ProdList
7920
Advantage
58
Suzhou Meishi Biotechnology Co., Ltd.
Tel
1173954148q
Email
meishipharma@126.com
Country
China
ProdList
20033
Advantage
58
Hubei Enxing Biotechnology Co., Ltd
Tel
16621771607
Email
exbio_tech@163.com
Country
China
ProdList
8189
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9266
Advantage
58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
Tel
+8613817748580
Fax
021-50175322
Email
cooperation@kean-chem.com
Country
China
ProdList
40066
Advantage
58
Dorne Chemical Technology co. LTD
Tel
+86-86-13583358881 +8618560316533
Email
Ethan@dornechem.com
Country
China
ProdList
3094
Advantage
58
airuikechemical co., ltd.
Tel
+86-18353166132 +86-18353166132
Email
sales02@airuikechemical.com
Country
China
ProdList
983
Advantage
58
Shanghai Acmec Biochemical Technology Co., Ltd.
Tel
+86-18621343501; +undefined18621343501
Email
product@acmec-e.com
Country
China
ProdList
33338
Advantage
58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43340
Advantage
58
Wuhan Topule Biopharmaceutical Co., Ltd
Tel
+8618327326525
Email
masar@topule.com
Country
China
ProdList
8467
Advantage
58
Hebei Miaoyin Technology Co.,Ltd
Tel
+86-17367732028 +86-17367732028
Email
kathy@hbyinsheng.com
Country
China
ProdList
3512
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
49982
Advantage
58
PT CHEM GROUP LIMITED
Tel
+86-85511178; +86-85511178;
Email
peter68@ptchemgroup.com
Country
China
ProdList
35425
Advantage
58
Hebei Shengyuan Jinlong Import and Export Co. LTD
Tel
+8617367750398
Email
info@hebeisyjl.com
Country
China
ProdList
1838
Advantage
58
Guangzhou Biocar Biotechnology Co.,Ltd.
Tel
+86-13397196830
Fax
027-86589876
Email
carrie@gzbiocar.cn
Country
China
ProdList
435
Advantage
58
Lanospharma Laboratories Co.,Ltd
Tel
--
Fax
--
Email
sales@lanospharma.com
Country
China
ProdList
6329
Advantage
56
More
Less

View Lastest Price from PAGOCLONE manufacturers

Dorne Chemical Technology co. LTD
Product
Pagoclone 133737-32-3
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
Shandong Hanjiang Chemical Co., Ltd
Product
PAGOCLONE 133737-32-3
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10T
Release date
2024-01-25
airuikechemical co., ltd.
Product
PAGOCLONE 133737-32-3
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
20 tons
Release date
2024-04-07

133737-32-3, PAGOCLONERelated Search:


  • 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone
  • RP 59037
  • Ip 456
  • Rp 62955
  • 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one
  • (+)-RP-59037; IP-456; RP-62955; CI-1043
  • CI-1043
  • AGOCLONE
  • inhibit,GABA Receptor,γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,IP 456,RP 62955,RP62955,Pagoclone,Inhibitor
  • (+)-Pagoclone
  • 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-3H-isoindol-1-one
  • 133737-32-3
  • C23H22ClN3O2