4-chloroquinoline-2-carbonitrile
- Product Name
- 4-chloroquinoline-2-carbonitrile
- CAS No.
- 4552-43-6
- Chemical Name
- 4-chloroquinoline-2-carbonitrile
- Synonyms
- 4-CHLORO-2-CYANOQUINOLINE;4-chloroquinoline-2-carbonitrile;2-Quinolinecarbonitrile, 4-chloro-
- CBNumber
- CB8845494
- Molecular Formula
- C10H5ClN2
- Formula Weight
- 188.61
- MOL File
- 4552-43-6.mol
4-chloroquinoline-2-carbonitrile Property
- Melting point:
- 109 °C
- Boiling point:
- 320.4±22.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -2.08±0.50(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C385130
- Product name
- 4-Chloroquinoline-2-carbonitrile
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- HCH0013047
- Product name
- 4-CHLORO-2-CYANOQUINOLINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1099.95
- Updated
- 2021/12/16
- Product number
- HCH0013047
- Product name
- 4-CHLORO-2-CYANOQUINOLINE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1690.74
- Updated
- 2021/12/16
- Product number
- HCH0013047
- Product name
- 4-CHLORO-2-CYANOQUINOLINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $2265.72
- Updated
- 2021/12/16
- Product number
- 6273AB
- Product name
- 4-Chloroquinoline-2-carbonitrile
- Packaging
- 5g
- Price
- $2304
- Updated
- 2021/12/16
4-chloroquinoline-2-carbonitrile Chemical Properties,Usage,Production
Preparation
synthesis of 4-chloroquinoline-2-carbonitrile: To a solution of 2,4-dichloroquinoline (444 mg, 2.24 mmol) in DMF (5 mL) was added zinc cyanide (117 mg, 1.14 mmol) and Pd(PPh3)4 (259 mg, 0.22 mmol). The reaction mixture was stirred at 120 °C for 1 h. A saturated NH4Cl solution (20 mL) was added and the mixture was extracted with ethyl acetate (3x5 mL). The organic layer was washed with a NaCl solution (5mL) and dried over sodium sulfate, filtered and evaporated. The product was further purified by chromatography on silica gel eluting with cyclohexane/ethyl acetate (95:5) to give 4-chloroquinoline-2-carbonitrile (392 mg, 2.085 mmol, 93 %) as a white solid.
4-chloroquinoline-2-carbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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