4-chloroquinoline-2-carbonitrile

Product Name: 4-chloroquinoline-2-carbonitrile
CAS No.: 4552-43-6
Chemical Name: 4-chloroquinoline-2-carbonitrile
Synonyms: 4-CHLORO-2-CYANOQUINOLINE;4-chloroquinoline-2-carbonitrile;2-Quinolinecarbonitrile, 4-chloro-
CBNumber: CB8845494
Molecular Formula: C10H5ClN2
Formula Weight: 188.61
MOL File: 4552-43-6.mol

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4-chloroquinoline-2-carbonitrile Property

Melting point:: 109 °C
Boiling point:: 320.4±22.0 °C(Predicted)
Density: 1.36±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -2.08±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C385130
Product name: 4-Chloroquinoline-2-carbonitrile
Packaging: 100mg
Price: $200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0013047
Product name: 4-CHLORO-2-CYANOQUINOLINE
Purity: 95.00%
Packaging: 1G
Price: $1099.95
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0013047
Product name: 4-CHLORO-2-CYANOQUINOLINE
Purity: 95.00%
Packaging: 2.5G
Price: $1690.74
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0013047
Product name: 4-CHLORO-2-CYANOQUINOLINE
Purity: 95.00%
Packaging: 5G
Price: $2265.72
Updated: 2021/12/16

AK Scientific

Product number: 6273AB
Product name: 4-Chloroquinoline-2-carbonitrile
Packaging: 5g
Price: $2304
Updated: 2021/12/16

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4-chloroquinoline-2-carbonitrile Chemical Properties,Usage,Production

Preparation

synthesis of 4-chloroquinoline-2-carbonitrile: To a solution of 2,4-dichloroquinoline (444 mg, 2.24 mmol) in DMF (5 mL) was added zinc cyanide (117 mg, 1.14 mmol) and Pd(PPh3)4 (259 mg, 0.22 mmol). The reaction mixture was stirred at 120 °C for 1 h. A saturated NH4Cl solution (20 mL) was added and the mixture was extracted with ethyl acetate (3x5 mL). The organic layer was washed with a NaCl solution (5mL) and dried over sodium sulfate, filtered and evaporated. The product was further purified by chromatography on silica gel eluting with cyclohexane/ethyl acetate (95:5) to give 4-chloroquinoline-2-carbonitrile (392 mg, 2.085 mmol, 93 %) as a white solid.

4-chloroquinoline-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-chloroquinoline-2-carbonitrile Suppliers

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4552-43-6, 4-chloroquinoline-2-carbonitrileRelated Search:

QUINOLINE-2-CARBONITRILE 4-CHLORO-PYRIDINE-2-CARBONITRILE 4-chloroquinoline-2-carbonitrile

4-CHLORO-2-CYANOQUINOLINE

4-chloroquinoline-2-carbonitrile

2-Quinolinecarbonitrile, 4-chloro-

4552-43-6