BAY 59-3074

Product Name: BAY 59-3074
CAS No.: 406205-74-1
Chemical Name: BAY 59-3074
Synonyms: CS-2278;BAY 59-3074;Bay 59-3074 ，S0412;BAY 59-3074;BAY-59-3074;Bay 59-3074, 10 mM in DMSO;BAY-59-3074; BAY 59-3074; BAY59-3074;inhibit,Cannabinoid Receptor,Bay 59-3074,Inhibitor,Bay 593074,Bay 59 3074;3-[2-Cyano-3-(trifluoromethyl)phenoxy]phenyl4,4,4-trifluoro-1-butanesulfonicacidester;1-Butanesulfonic acid, 4,4,4-trifluoro-, 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl ester
CBNumber: CB8846466
Molecular Formula: C18H13F6NO4S
Formula Weight: 453.36
MOL File: 406205-74-1.mol

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BAY 59-3074 Property

Boiling point:: 490.6±45.0 °C(Predicted)
Density: 1.49±0.1 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: DMSO:56.78(Max Conc. mg/mL);135.05(Max Conc. mM)
Ethanol:68.17(Max Conc. mg/mL);162.14(Max Conc. mM)
form: A crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21036
Product name: BAY 59-3074
Purity: ≥98%
Packaging: 1mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 21036
Product name: BAY 59-3074
Purity: ≥98%
Packaging: 5mg
Price: $130
Updated: 2024/03/01

Cayman Chemical

Product number: 21036
Product name: BAY 59-3074
Purity: ≥98%
Packaging: 10mg
Price: $214
Updated: 2024/03/01

Cayman Chemical

Product number: 21036
Product name: BAY 59-3074
Purity: ≥98%
Packaging: 50mg
Price: $844
Updated: 2024/03/01

Tocris

Product number: 2500
Product name: Bay59-3074
Purity: ≥99%(HPLC)
Packaging: 10
Price: $167
Updated: 2021/12/16

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BAY 59-3074 Chemical Properties,Usage,Production

Uses

Bay 59-3074, is a novel cannabinoid CB1/CB2 receptor partial agonist with antihyperalgesic and antiallodynic effects.

Definition

ChEBI: 4,4,4-trifluoro-1-butanesulfonic acid is an aromatic ether.

Biological Activity

Novel CB 1 /CB 2 receptor partial agonist (K i values are 48.3 and 45.5 nM at human CB 1 and CB 2 receptors respectively). Orally active CB 1 agonist in vivo . Displays anti-hyperalgesic and antiallodynic properties in rat models of chronic neuropathic and inflammatory pain.

in vivo

BAY 59-3074 (0.3-3 mg/kg; oral administration; daily; for 2 weeks; male Wistar rats) treatment improves antihyperalgesic and antiallodynic effects against thermal or mechanical stimuli in rat models of chronic neuropathic and inflammatory pain.

Animal Model:	Male Wistar rats (160-250 g)^[1]
Dosage:	0.3 mg/kg, 1 mg/kg, and 3 mg/kg
Administration:	Oral administration; daily; for 2 weeks.
Result:	Antiallodynic efficacy in the spared nerve injury model was maintained after 2 weeks of daily administration. Tolerance developed rapidly (within 5 days) for cannabinoid-related side effects. Antihyperalgesic and antiallodynic efficacy was maintained/increased.

IC 50

CB1: 48.3 nM (Ki); CB2: 45.5 nM (Ki)

BAY 59-3074 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY 59-3074 Suppliers

China 74 Germany 1 India 1 Japan 2 United Kingdom 1 United States 10 Global 89

Shanghai Boyle Chemical Co., Ltd.

Tel
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Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
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Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
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BOC Sciences

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Email: info@bocsci.com
Country: United States
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Haoyuan Chemexpress Co., Ltd.

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Email: info@chemexpress.com
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Shanghai Balmxy Pharmaceutical Co., Ltd

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Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
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Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
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EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

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View Lastest Price from BAY 59-3074 manufacturers

Career Henan Chemical Co

Product: [3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl] 4,4,4-trifluorobutane-1-sulfonate 406205-74-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-01-01

406205-74-1, BAY 59-3074Related Search:

2-(Trifluoromethyl)benzonitrile BAY 59-3074 3-Methoxyphenyl methanesulfonate 2-METHOXY-6-METHYLBENZONITRILE 2-HYDROXY-6-METHYL-BENZONITRILE

BAY 59-3074

3-[2-Cyano-3-(trifluoromethyl)phenoxy]phenyl4,4,4-trifluoro-1-butanesulfonicacidester

CS-2278

BAY-59-3074; BAY 59-3074; BAY59-3074

BAY 59-3074;BAY-59-3074

1-Butanesulfonic acid, 4,4,4-trifluoro-, 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl ester

inhibit,Cannabinoid Receptor,Bay 59-3074,Inhibitor,Bay 593074,Bay 59 3074

Bay 59-3074, 10 mM in DMSO

Bay 59-3074 ，S0412

406205-74-1

C18H13F6NO4S

Pharmaceutical intermediate