ChemicalBook > CAS DataBase List > LY 344864

LY 344864

Product Name
LY 344864
CAS No.
186544-26-3
Chemical Name
LY 344864
Synonyms
CS-660;Y344864;LY 344864;LY344864 HCL;LY344864;LY-344864;LY 344864 hydrochloride;(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide;Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-;(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride;N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
CBNumber
CB8847478
Molecular Formula
C21H22FN3O
Formula Weight
351.42
MOL File
186544-26-3.mol
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LY 344864 Property

Boiling point:
471.9±45.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
DMSO : ≥ 350 mg/mL (995.96 mM)
pka
14.12±0.40(Predicted)
form 
Powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2451
Product name
LY344864 hydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$214
Updated
2021/12/16
Tocris
Product number
2451
Product name
LY344864 hydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$884
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
71157
Product name
LY-344864HCl
Packaging
50mg
Price
$1175
Updated
2021/12/16
Matrix Scientific
Product number
095130
Product name
(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
Purity
95+%
Packaging
1g
Price
$4725
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
71157
Product name
LY-344864HCl
Packaging
10mg
Price
$660
Updated
2021/12/16
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LY 344864 Chemical Properties,Usage,Production

Uses

LY-344864 Hydrochloride is used as a selective 5-HTIF receptor agonist.

Biological Activity

Potent, selective 5-HT 1F receptor agonist (EC 50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (K i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μ M for 5-HT 1F , 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 2A and 5-HT 7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration.

LY 344864 Preparation Products And Raw materials

Raw materials

Preparation Products

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LY 344864 Suppliers

China 41 Germany 1 United Kingdom 2 United States 14 Global 58
J & K SCIENTIFIC LTD.
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View Lastest Price from LY 344864 manufacturers

Career Henan Chemical Co
Product
LY 344864 186544-26-3
Price
US $1.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-24

186544-26-3, LY 344864Related Search:

(R)-3-Amino-1,2,3,4-tetrahydrocarbazole Ciclindole 3-(2-DIMETHYLAMINO-ETHYL)-1H-INDOL-5-YLAMINE 3-Amino-1,2,3,4-tetrahydrocarbazol LY 344864

  • LY 344864
  • LY 344864 hydrochloride
  • N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
  • (R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide
  • (R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
  • LY344864 HCL
  • LY344864;LY-344864
  • CS-660
  • Y344864
  • Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-
  • migraines,Adrenergic Receptor,BBB penetration,Serotonin Receptor,inhibit,5-HT Receptor,LY-344864,Beta Receptor,Parkinson’s disease,LY 344864,Inhibitor,5-hydroxytryptamine Receptor,5-HT1F
  • 186544-26-3
  • C21H22N3OFHCl
  • Inhibitors