ChemicalBook > CAS DataBase List > LY 344864

LY 344864

Product Name
LY 344864
CAS No.
186544-26-3
Chemical Name
LY 344864
Synonyms
CS-660;Y344864;LY 344864;LY344864 HCL;LY344864;LY-344864;LY 344864 hydrochloride;(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide;Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-;(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride;N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
CBNumber
CB8847478
Molecular Formula
C21H22FN3O
Formula Weight
351.42
MOL File
186544-26-3.mol
More
Less

LY 344864 Property

Boiling point:
471.9±45.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
DMSO : ≥ 350 mg/mL (995.96 mM)
pka
14.12±0.40(Predicted)
form 
Powder
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
2451
Product name
LY344864 hydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$214
Updated
2021/12/16
Tocris
Product number
2451
Product name
LY344864 hydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$884
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
71157
Product name
LY-344864HCl
Packaging
50mg
Price
$1175
Updated
2021/12/16
Matrix Scientific
Product number
095130
Product name
(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
Purity
95+%
Packaging
1g
Price
$4725
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
71157
Product name
LY-344864HCl
Packaging
10mg
Price
$660
Updated
2021/12/16
More
Less

LY 344864 Chemical Properties,Usage,Production

Uses

LY-344864 Hydrochloride is used as a selective 5-HTIF receptor agonist.

Biological Activity

Potent, selective 5-HT 1F receptor agonist (EC 50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (K i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μ M for 5-HT 1F , 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 2A and 5-HT 7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration.

LY 344864 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

View Lastest Price from LY 344864 manufacturers

Career Henan Chemical Co
Product
LY 344864 186544-26-3
Price
US $1.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-24

186544-26-3, LY 344864Related Search:


  • LY 344864
  • LY 344864 hydrochloride
  • N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
  • (R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide
  • (R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
  • LY344864 HCL
  • LY344864;LY-344864
  • CS-660
  • Y344864
  • Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-
  • migraines,Adrenergic Receptor,BBB penetration,Serotonin Receptor,inhibit,5-HT Receptor,LY-344864,Beta Receptor,Parkinson’s disease,LY 344864,Inhibitor,5-hydroxytryptamine Receptor,5-HT1F
  • 186544-26-3
  • C21H22N3OFHCl
  • Inhibitors