((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE

Product Name
((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE
CAS No.
52685-51-5
Chemical Name
((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE
Synonyms
4-Iodobut-3-en-2-yl(trimethyl)silane;((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE;Silane, [(1E)-3-iodo-1-methyl-1-propen-1-yl]trimethyl-
CBNumber
CB8850795
Molecular Formula
C7H15ISi
Formula Weight
254.18
MOL File
52685-51-5.mol
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((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE Property

Boiling point:
188.9±23.0 °C(Predicted)
Density 
1.323±0.06 g/cm3(Predicted)
solubility 
freely sol organic solvents.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
ORS0003597
Product name
((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE
Purity
95.00%
Packaging
5MG
Price
$501.63
Updated
2021/12/16
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((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE Chemical Properties,Usage,Production

Physical properties

bp 60 °C/20 mmHg.

Uses

(E)-1-Iodo-3-trimethylsilyl-2-butene can be used as annulation reagent; alkylative equivalent of 3-buten-2-one; 3-ketobutyl synthon.

Preparation

the first reported preparation of this reagent lacked full experimental details. The preparation given is a compilation of thework of several groups; the various steps have been selected to give optimum yields. 2-Propyn-1-ol is converted3 into its 3-(trimethylsilyl) derivative (1), which is then reduced4 using sodium bis(2-methoxyethoxy)aluminum hydride (Red-Al). The intermediate vinylaluminum is reacted with iodine to produce the (Z)-iodoalkene (2). Treatment of this with lithium dimethylcuprate gives the allylic alcohol (3);. transformation into (E)-(3-chloro-1-methyl-1-propenyl)trimethylsilane (4) followed by halogen exchange with sodium iodide then gives reagent (5).

((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE Preparation Products And Raw materials

Raw materials

Preparation Products

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((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE Suppliers

Suzhou Rovathin Foreign Trade Co.,Ltd
Tel
0512-65816829 18662214788
Fax
0512-65816829
Email
info@rovathin.com.cn
Country
China
ProdList
9597
Advantage
58

52685-51-5, ((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANERelated Search:


  • ((E)-3-IODO-1-METHYLPROPENYL)-TRIMETHYLSILANE
  • 4-Iodobut-3-en-2-yl(trimethyl)silane
  • Silane, [(1E)-3-iodo-1-methyl-1-propen-1-yl]trimethyl-
  • 52685-51-5