2-Aminobenzenethiol Property

Melting point:

23 °C

Boiling point:

70-72 °C0.2 mm Hg(lit.)

Density 

1.17 g/mL at 25 °C(lit.)

vapor pressure 

1 hPa (69 °C)

refractive index 

n20/D 1.642(lit.)

Flash point:

175 °F

storage temp. 

Store at <= 20°C.

solubility 

H2O: slightly soluble

pka

pK1: <2(+1);pK2: 7.90(0) (25°C)

form 

Liquid

color 

Clear yellow to amber

Water Solubility 

INSOLUBLE

Sensitive 

Stench

BRN 

606076

Stability:

Air Sensitive

InChIKey

VRVRGVPWCUEOGV-UHFFFAOYSA-N

CAS DataBase Reference

137-07-5(CAS DataBase Reference)

NIST Chemistry Reference

Benzenethiol, 2-amino-(137-07-5)

EPA Substance Registry System

Benzenethiol, 2-amino- (137-07-5)

Safety

Hazard Codes 

C,N

Risk Statements 

22-34-50/53-37-20/21/22

Safety Statements 

26-36/37/39-45-60-61-25-27

RIDADR 

UN 1760 8/PG 3

WGK Germany 

3

RTECS 

DC0600000

F 

9-13-23

Hazard Note 

Corrosive/Stench

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29309070

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H400Very toxic to aquatic life

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-Aminobenzenethiol Chemical Properties,Usage,Production

Chemical Properties

clear yellow to amber liquid

Uses

2-Aminothiophenol was used in the synthesis of 1,5-benzothiazepines derivatives by reacting with 1,3-diphenylpropenone derivatives and using aluminosilicate solid catalysts. It was also used in the synthesis of benzothiazole2 and 3-(benzothiazol-2-yl)coumarin derivatives. The ternary complexes of copper (II) with salicylidene-2-aminothiophenol (L) and glycine, alanine, valine and histidene amino acids.

Uses

A multifunctional compound which shows antioxidant activity in a skin cell model of UVA-induced stress.

Uses

2-Aminothiophenol was used in one-pot synthesis of stable phosphonium ylides. It was also used in the synthesis of 2-[(2-benzothiazolylmethyl)thio]-benzenamine. It was used to functionalize silver nano particles for biological pH sensing based on surface enhanced Raman scattering.

Definition

ChEBI: 2-aminothiophenol is an aryl thiol that is thiophenol substituted at position 2 by an amino group. It has a role as a plant metabolite. It is a substituted aniline and an aryl thiol.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1514, 1946 DOI: 10.1021/ja01212a038

General Description

2-Aminothiophenol couples with Amberlite XAD by means of an N=N spacer to prepare a new functionalized resin for on-line preconcentration of copper and cadmium.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. Moderately flammable. Can react with oxilzing materials. To fight fire, use water, foam, CO2, mist or spray, dry chemical