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Bucumolol

Product Name
Bucumolol
CAS No.
58409-59-9
Chemical Name
Bucumolol
Synonyms
Bucumolol;dl-Bucumolol;8-[3-(tert-Butylamino)-2-hydroxypropoxy]-5-methylcoumarin;8-[2-Hydroxy-3-(tert-butylamino)propoxy]-5-methylcoumarin;8-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-2H-1-benzopyran-2-one
CBNumber
CB8875453
Molecular Formula
C17H23NO4
Formula Weight
305.37
MOL File
58409-59-9.mol
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Bucumolol Property

Melting point:
>163° (dec.)
Boiling point:
490.7±45.0 °C(Predicted)
Density 
1.160±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
13.81±0.20(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B689395
Product name
Bucumolol
Packaging
25mg
Price
$2240
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008654
Product name
BUCUMOLOL
Purity
95.00%
Packaging
5MG
Price
$498.97
Updated
2021/12/16
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Bucumolol Chemical Properties,Usage,Production

Originator

Bucumarol,Sankyo,Japan,1982

Uses

Bucumolol is?an antihypertensive agent and a β-adrenoceptor blocker.

Definition

ChEBI: Bucumolol is a member of coumarins.

Manufacturing Process

A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for 15 hours. The reaction mixture is concentrated under reduced pressure to dryness. The residue is recrystallized from a mixture of ethanol and ether to give 2.1 g of the desired product melting at 226° to 228°C (with decomposition).
In practice it is usually used as hydrochloride.

Therapeutic Function

Beta-adrenergic blocker

Bucumolol Preparation Products And Raw materials

Raw materials

Preparation Products

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Bucumolol Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
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32165
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United States Biological
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chemicals@usbio.net
Country
United States
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6214
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Waterstone Technology, LLC
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Email
sales@waterstonetech.com
Country
United States
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6786
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2A PharmaChem USA
Tel
--
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Email
sales@2apharmachem.com
Country
United States
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3B Scientific Corporation
Tel
--
Fax
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Email
sales@3bsc.com
Country
United States
ProdList
6718
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58409-59-9, BucumololRelated Search:


  • Bucumolol
  • dl-Bucumolol
  • 8-[2-Hydroxy-3-(tert-butylamino)propoxy]-5-methylcoumarin
  • 8-[3-(tert-Butylamino)-2-hydroxypropoxy]-5-methylcoumarin
  • 8-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-2H-1-benzopyran-2-one
  • 58409-59-9