ChemicalBook > CAS DataBase List > pyridoxamine
pyridoxamine
- Product Name
- pyridoxamine
- CAS No.
- 85-87-0
- Chemical Name
- pyridoxamine
- Synonyms
- Pyridoxylamine;Pyridorin;PyridoxaMine-d4;pyridoxamine USP/EP/BP;Pyridoxylamine, 10 mM in DMSO;4-(aminomethyl)-2-methyl-5-methylol-pyridin-3-ol;4-Aminomethyl-5-hydroxy-6-methyl-3-pyridinemethanol;inhibit,Inhibitor,Pyridoxylamine,Endogenous Metabolite;3-Pyridinemethanol, 4-(aminomethyl)-5-hydroxy-6-methyl-;4-(aminomethyl)-5-(hydroxymethyl)-2-methyl-pyridin-3-ol
- CBNumber
- CB8895262
- Molecular Formula
- C8H12N2O2
- Formula Weight
- 168.19
- MOL File
- 85-87-0.mol
More
Less
pyridoxamine Property
- Melting point:
- 193-193.5 °C
- Boiling point:
- 460.1±40.0 °C(Predicted)
- Density
- 1.282±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.98±0.10(Predicted)
- color
- Pale Yellow
- Stability:
- Hygroscopic
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- A470870
- Product name
- 4-(Aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
- Packaging
- 50mg
- Price
- $85
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 037404
- Product name
- 4-(Aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
- Purity
- 95%
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 037404
- Product name
- 4-(Aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
- Purity
- 95%
- Packaging
- 1g
- Price
- $146
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0013764
- Product name
- Pyridoxylamine
- Purity
- 99.81%
- Packaging
- 100mg
- Price
- $160
- Updated
- 2021/12/16
AK Scientific
- Product number
- M867
- Product name
- Pyridoxamine
- Packaging
- 500mg
- Price
- $192
- Updated
- 2021/12/16
More
Less
pyridoxamine Chemical Properties,Usage,Production
Uses
Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions.
Definition
ChEBI: Pyridoxamine is a monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a mouse metabolite, an iron chelator and a nephroprotective agent. It is a hydroxymethylpyridine, a monohydroxypyridine, an aminoalkylpyridine and a vitamin B6. It is a conjugate base of a pyridoxaminium(1+).
in vivo
Pyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo[1].
IC 50
Human Endogenous Metabolite
References
[1] Stitt A, et al. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes. 2002 Sep;51(9):2826-32. DOI:10.2337/diabetes.51.9.2826
pyridoxamine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
pyridoxamine Suppliers
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
- Tel
- 021-58958002 18930822973
- Fax
- +86 (21) 5895-8628
- sales@uhnshanghai.com
- Country
- China
- ProdList
- 998
- Advantage
- 58
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15873
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 021-31433387 15618786686
- Fax
- QQ:1369748377
- sales@rechemscience.com
- Country
- China
- ProdList
- 2991
- Advantage
- 58
- Tel
- 400-400-1332688 18019345275
- Fax
- 400-133-2688
- amy@rhawn.cn
- Country
- China
- ProdList
- 14948
- Advantage
- 58
- Tel
- 028-85157043 15882256948
- 676046971@qq.com
- Country
- China
- ProdList
- 4181
- Advantage
- 58
- Tel
- 010-62971590 18548936886
- Fax
- 010-62340519
- 3462612863@qq.com
- Country
- China
- ProdList
- 10063
- Advantage
- 58
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
- Country
- China
- ProdList
- 57422
- Advantage
- 58
- Tel
- +86-0551-65418671 +8618949823763
- Fax
- 0551-65418697
- sales@tnjchem.com
- Country
- China
- ProdList
- 34563
- Advantage
- 58
- Tel
- 02768782018 18771942761
- sales01@whmonad.com
- Country
- CHINA
- ProdList
- 979
- Advantage
- 58
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11218
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29798
- Advantage
- 58
- Tel
- 13348960310
- 3003867561@qq.com
- Country
- China
- ProdList
- 10503
- Advantage
- 58
- Tel
- 021-61109150
- Fax
- 021-61105897
- sales@tcisct.com
- Country
- China
- ProdList
- 29668
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 59936
- Advantage
- 58
- Tel
- 13549236410
- sales@invivochem.cn
- Country
- China
- ProdList
- 6753
- Advantage
- 58
- Tel
- 029-029-81120477 17792793610
- 1033@dideu.com
- Country
- China
- ProdList
- 9963
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58
- Tel
- 15901636993
- 455096425@qq.com
- Country
- China
- ProdList
- 231
- Advantage
- 58
- Tel
- 18621169109
- market03@meryer.com
- Country
- China
- ProdList
- 27987
- Advantage
- 58
- Tel
- 025-025-66113011 18626450290
- cb5@aikonchem.com
- Country
- China
- ProdList
- 10358
- Advantage
- 58
- Tel
- 027-027-16602739303 16602739303
- 673003916@qq.com
- Country
- China
- ProdList
- 2935
- Advantage
- 58
- Tel
- 0571-8512-5372
- sales@bingochem.com
- Country
- China
- ProdList
- 21669
- Advantage
- 58
- Tel
- 025-85560043 15850508050
- Fax
- 025-85563444
- cindy.huang@synzest.com
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- 400-821-026
- Sales@sangon.com
- Country
- China
- ProdList
- 6710
- Advantage
- 58
- Tel
- 0519-82111935 15195055733
- Fax
- 051982611250
- info@feifanchem.com
- Country
- China
- ProdList
- 618
- Advantage
- 58
- Tel
- +86-13017695106 +86-13676922317
- jiuyitime@fdachem.com
- Country
- China
- ProdList
- 16513
- Advantage
- 58
- Tel
- +8618764156297
- info@getchem.com
- Country
- China
- ProdList
- 7841
- Advantage
- 58
- Tel
- +86-86-13583358881 +8618560316533
- Brad@rongnabiotech.com
- Country
- China
- ProdList
- 3387
- Advantage
- 58
- Tel
- +86-88938639 +86-17705817739
- info@dycnchem.com
- Country
- China
- ProdList
- 53899
- Advantage
- 58
- Tel
- +8618950047208
- ellena@amitychem.com
- Country
- China
- ProdList
- 43416
- Advantage
- 58
- Tel
- +8613817748580
- Fax
- 021-50175322
- cooperation@kean-chem.com
- Country
- China
- ProdList
- 40066
- Advantage
- 58
- Tel
- +86-18621343501; +undefined18621343501
- product@acmec-e.com
- Country
- China
- ProdList
- 33338
- Advantage
- 58
- Tel
- +86-89586680 +86-13289823923
- 1026@dideu.com
- Country
- China
- ProdList
- 9080
- Advantage
- 58
- Tel
- +86-571-87711850
- market18@leapchem.com
- Country
- China
- ProdList
- 24727
- Advantage
- 58
- Tel
- 13802441876
- Country
- CHINA
- ProdList
- 194
- Advantage
- 58
- Tel
- 15017560539
- Country
- CHINA
- ProdList
- 142
- Advantage
- 58
- Tel
- 18312220236
- Country
- CHINA
- ProdList
- 178
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@tritonchemtech.com
- Country
- China
- ProdList
- 209
- Advantage
- 38
- Tel
- --
- Fax
- --
- chenjw@absin.cn
- Country
- CHINA
- ProdList
- 6208
- Advantage
- 58
- Tel
- --
- Fax
- --
- Proteintech-CN@ptglab.com
- Country
- CHINA
- ProdList
- 6290
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@zzsrm.com
- Country
- CHINA
- ProdList
- 6650
- Advantage
- 58
More
Less
View Lastest Price from pyridoxamine manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- Pyridoxylamine 85-87-0
- Price
- US $22.00-88.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2025-06-25
Wuhan Monad Medicine Tech Co.,LTD
- Product
- pyridoxamine 85-87-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99.99%
- Supply Ability
- 20 tons/month
- Release date
- 2021-04-16
Career Henan Chemical Co
- Product
- pyridoxamine 85-87-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-09
85-87-0, pyridoxamineRelated Search:
Chlorphenamine maleate
Cefepime
Ciclopirox ethanolamine
Chloropyramine hydrochloride
Novaluron
Diflufenican
L-Lysine
Pyridoxine
Pyrrole
Pyridine
4-Aminobenzoic acid
Selegiline