Chloropyramine hydrochloride

Product Name: Chloropyramine hydrochloride
CAS No.: 6170-42-9
Chemical Name: Chloropyramine hydrochloride
Synonyms: CHLOROPYRAMINE HCL;Chloropyramine HCI;Nilfan;Alergosan;Halopyramine hydrochloride;CHLOROPYRAMINE HYDROCHLORIDE;CHLOROPYRAMINE MONOHYDROCHLORIDE;Chloropyramine hydrochloride salt;3-chloro-2H-pyran-2-amine hydrochloride;N-P-CHLOROBENZYL-N,N-DIMETHYL-N-(2-PYRIDYL)ETHYLENEDIAMINE HYDROCHLORIDE
CBNumber: CB4495475
Molecular Formula: C16H21Cl2N3
Formula Weight: 326.26
MOL File: 6170-42-9.mol

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Chloropyramine hydrochloride Property

Melting point:: 172-174°
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
CAS DataBase Reference: 6170-42-9(CAS DataBase Reference)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C1915
Product name: Chloropyramine hydrochloride
Purity: analytical standard, for drug analysis
Packaging: 1g
Price: $14.4
Updated: 2024/03/01

Alfa Aesar

Product number: J60350
Product name: Chloropyramine hydrochloride
Packaging: 1g
Price: $32.65
Updated: 2024/03/01

TRC

Product number: C381268
Product name: Chloropyramine hydrochloride
Packaging: 1g
Price: $125
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001961
Product name: CHLOROPYRAMINE HYDROCHLORIDE
Purity: 95.00%
Packaging: 1G
Price: $131.25
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC149051
Product name: Chloropyramine HCl
Packaging: 5G
Price: $150
Updated: 2021/12/16

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Chloropyramine hydrochloride Chemical Properties,Usage,Production

Originator

Chloropyramine,Vramed

Uses

synthetic

Uses

Chloropyramine hydrochloride is a neurotransmitter related agent for research of drug analysis. Also, it is designed to disrupt the focal adhesion kinase (FAK) and vascular endothelial growth factor receptor-3 (VEGFR-3) interaction in neuroblastoma.

Manufacturing Process

A solution comprising 40 parts of 2-bromopyridine, 100 parts of N,N-dimethylN'-(4-chlorobenzyl)ethylenediamine and 100 parts of quinoline is heated at 140-145°C for 5 hours. The oil layer after washing with 30% sodium hydroxide solution is distilled, and the fraction which distills at 142-170°C/1 mm is collected. This oil is converted to the monohydrochloride and recrystallized from a mixture of amyl alcohol and ether. The monohydrochloride salt of N,N-dimethyl-N'-(4-chlorobenzyl)-N'-(2-pyridyl) ethylenediamine is obtained which melts at 167-168.4°C.
N,N-Dimethyl-N'-(4-chlorobenzyl)-N'-(2-pyridyl)ethylenediamine may be prepared by another method:
To a mixture of 100 ml of liquid ammonia and about 80 mg of black iron oxide was added 0.78 g (0.02 atom) of potassium. When all of the potassium had reacted, 3.3 g of N,N-dimethyl-N'-(2-pyridyl)ethylenediamine was added. After the addition of 75 ml of dry toluene the ammonia was removed on the steam bath. To the cooled and stirred mixture was added 4.26 g of p-chlorobenzyl chloride, and the reaction mixture was stirred on the steam bath for 11 hours. It was then filtered and concentrated to an oil. This concentrate was taken up in ether, and the ethereal solution was washed with water, dried over sodium sulfate, and concentrated. Distillation gave 2.96 g of yellow liquid. Treatment of this distillate with an equivalent quantity of hydrogen chloride in absolute alcohol and precipitation by the addition of anhydrous ether gave 2.33 g of the N,N-dimethyl-N'-(4-chlorobenzyl)-N'-(2-pyridyl)ethylenediamine hydrochloride.

Therapeutic Function

Antihistaminic

Chloropyramine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Chloropyramine hydrochloride Suppliers

China 60 Germany 2 India 4 Switzerland 3 United Kingdom 5 United States 19 USA 1 Global 94

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29785
Advantage: 68

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Wuhan Magic Biological Technology Co., Ltd.

Tel: 18872289958、027-52304252、3400508168
Fax: 027-52304252
Email: 3400508168@qq.com
Country: China
ProdList: 1910
Advantage: 55

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718 +86-13336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29791
Advantage: 60

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
ProdList: 15494
Advantage: 58

Shijiazhuang Leather Bureau Chemical Technology Co., Ltd.

Tel: 13020863400
Email: liaoy124@163.com
Country: China
ProdList: 307
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32038
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52849
Advantage: 58

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View Lastest Price from Chloropyramine hydrochloride manufacturers

Henan Fengda Chemical Co., Ltd

Product: Chloropyramine hydrochloride 6170-42-9
Price: US $50.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-22

Career Henan Chemical Co

Product: Chloropyramine hydrochloride 6170-42-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-11

6170-42-9, Chloropyramine hydrochlorideRelated Search:

ETHANE Chloropyramine Pioglitazone hydrochloride Ethylenediamine dihydrochloride Cefeprime dihydrochloride Methoxyammonium chloride N,N-Dimethylformamide N,N,N',N'-Tetramethylethylenediamine Metoclopramide hydrochloride Pyridine hydrochloride Topotecan hydrochloride Dimethyl carbonate Dimethyl ether Dimethyl fumarate Dimethyl sulfoxide 2,6-Lutidine Triprolidine hydrochloride TRIPELENNAMINE HYDROCHLORIDE

CHLOROPYRAMINE HCL

CHLOROPYRAMINE HYDROCHLORIDE

CHLOROPYRAMINE MONOHYDROCHLORIDE

N-P-CHLOROBENZYL-N,N-DIMETHYL-N-(2-PYRIDYL)ETHYLENEDIAMINE HYDROCHLORIDE

N-P-CHLOROBENZYL-N',N'-DIMETHYL-N-[2-PYRIDYL]ETHYLENEDIAMINE HYDROCHLORIDE

N-P-CHLOROBENZYL-N',N'-DIMETHYL-N-[2-PYRIDYL]LETHYLENEDIAMINE HYDROCHLORIDE

N1-(4-Chlorobenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride

Chloropyramine HCI

N-[(4-chlorophenyl)methyl]-N’,N’-dimethyl-N-2-pyridinyl-1,2-ethanediamine

3-chloro-2H-pyran-2-amine hydrochloride

Chloropyramine hydrochloride salt

Nilfan

Halopyramine hydrochloride

Alergosan

Vascular endothelial growth factor receptor,FAK,inhibit,PTK2,Chloropyramine hydrochloride,VEGFR,Chloropyramine,Focal adhesion kinase,PTK2 protein tyrosine kinase 2,Histamine Receptor,Inhibitor

N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine,hydrochloride

N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine

6170-42-9

C16H20ClN3HCl

C16H20ClN3ClH

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