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Cefeprime dihydrochloride

Product Name
Cefeprime dihydrochloride
CAS No.
107648-80-6
Chemical Name
Cefeprime dihydrochloride
Synonyms
CEFEPIME HCL;Cefepime DiHCl;Cefepime Impurity 16;CefepiMe hydrochloric;Cefepime Hydrochlorede;CEFEPIME DIHYDROCHLORIDE;CEFEPRIME DIHYDROCHLORIDE;CEFEPIME HCL STERILE POWDER;Cefepime Hydrochloride/arginine;Cefeprime dihydrochloride USP/EP/BP
CBNumber
CB3739703
Molecular Formula
C19H25ClN6O5S2
Formula Weight
553.49
MOL File
107648-80-6.mol
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Cefeprime dihydrochloride Property

Melting point:
230 °C (decomp)
solubility 
Water:10.0(Max Conc. mg/mL);17.5(Max Conc. mM)
DMSO:6.0(Max Conc. mg/mL);10.5(Max Conc. mM)
CAS DataBase Reference
107648-80-6(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C242765
Product name
CefepimeDihydrochloride
Packaging
10mg
Price
$130
Updated
2021/12/16
AvaChem
Product number
2437
Product name
Cefepime Dihydrochloride
Packaging
5g
Price
$189
Updated
2021/12/16
Chemenu
Product number
CM126625
Product name
1-(((6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-methylpyrrolidin-1-iumchloridehydrochloride
Purity
97%
Packaging
1g
Price
$234
Updated
2021/12/16
Crysdot
Product number
CD00013211
Product name
Cefepime hydrochloride
Purity
97%
Packaging
1g
Price
$248
Updated
2021/12/16
AvaChem
Product number
2437
Product name
Cefepime Dihydrochloride
Packaging
25g
Price
$590
Updated
2021/12/16
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Cefeprime dihydrochloride Chemical Properties,Usage,Production

Description

Cefepime Hydrochloride is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad-spectrum bactericidal activity. Administered parenterally, cefepime inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in a reduction of bacterial cell wall stability and cell lysis. This agent is more active against a variety of Gram-positive pathogens compared to third-generation cephalosporins.

Uses

Cefepime hydrochloride has been used as a pharmaceutical reference standard for the determination of analytes in pharmaceutical preparations by spectrophotometric and chromatographic techniques. Cefepime is commonly used in the treatment of severe atypical pneumonia and infections caused by multi-drug resistant microorganisms (e.g. Pseudomonas aeruginosa), and is also indicated for the empirical treatment of febrile neutropenia.

Definition

ChEBI: Cefepime hydrochloride is a hydrochloride that is the monohydrate of the dihydrochloride salt of cefepime. It has a role as an antibacterial drug. It is a hydrochloride, a hydrate and a cephalosporin. It contains a cefepime(1+).

Cefeprime dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefeprime dihydrochloride Suppliers

Qilu Pharmaceutical Co. Ltd.
Tel
0531-83128685
Email
hui.ma@qilu-pharma.com
Country
China
ProdList
17
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-83991130 18627774460
Fax
027-83991130
Email
1718093273@QQ.COM
Country
China
ProdList
1882
Advantage
58
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8844
Advantage
52
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2876
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
Shanghai QianJin Chemical Technology Co., Ltd
Tel
021-20900665 17321230821
Fax
021-20900665
Email
2986274987@qq.com
Country
China
ProdList
900
Advantage
55
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Hangzhou Dingyan Chem Co., LTD
Tel
0571-87157530-8002 15267169049
Fax
0571-87156470
Email
sales@dingyanchem.com
Country
China
ProdList
2190
Advantage
58
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View Lastest Price from Cefeprime dihydrochloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Cefepime Hydrochloride 107648-80-6
Price
US $1.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10mt
Release date
2024-10-30
Weijer International Trade (Hebei) Co., Ltd
Product
Cefepime Dihydrochloride 107648-80-6
Price
US $300.00/KG
Min. Order
1KG
Purity
>99%
Supply Ability
50000kg/Month
Release date
2023-03-09
Anhui Rencheng Technology Co., Ltd
Product
Cefepime Dihydrochloride 107648-80-6
Price
US $250.00/KG
Min. Order
0.5KG
Purity
>99%
Supply Ability
20tons
Release date
2021-01-09

107648-80-6, Cefeprime dihydrochlorideRelated Search:


  • CEFEPIME HCL STERILE POWDER
  • CEFEPRIME DIHYDROCHLORIDE
  • (6R,7R)-7-[[(2E)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride hydrochloride
  • PyrrolidiniuM,1-[[(6R,7R)-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-2-(Me
  • CefepiMe hydrochloric
  • PyrrolidiniuM,1-[[(6R,7R)-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]-1-Methyl-,chloride, hydrochloride (1:1:1
  • CEFEPIME DIHYDROCHLORIDE
  • CEFEPIME HCL
  • 1-(((6R,7R)-7-((Z)-2-(2-aMinothiazol-4-yl)-2-(MethoxyiMino)acetaMido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)Methyl)-1-Methylpyrrolidin-1-iuM chloride hydrochloride
  • Cefepime Hydrochloride/arginine
  • Cefepime Hydrochlorede
  • 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-pyrrolidinium chloride hydrochloride
  • Cefepime Dihydrochloride : L(+)-Arginine
  • Cefepime Impurity 16
  • Cefeprime dihydrochloride USP/EP/BP
  • TIANFU CHEM-- Cefeprime dihydrochloride
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  • 107648-80-6
  • C19H24N6O5S22HCl
  • C19H24N6O5S22HCLH2O
  • C19H25N6O5S2ClHCl
  • C19H26Cl2N6O5S2
  • Pharmaceutical intermediate
  • Cefepime