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Cefepime hydrochloride

Product Name
Cefepime hydrochloride
CAS No.
123171-59-5
Chemical Name
Cefepime hydrochloride
Synonyms
Maxipime;Cefepime Hydrocloride;Cefepim dihydrochloride;CefepiMe dihydrochloride hydrate;Cefepime dihydrochloride monohydrate for system suitability CRS;Axepim;Cepimex;CEPEFIME HCL;Cefepime 2HCl;efepime hydrochloride
CBNumber
CB8691453
Molecular Formula
C19H28Cl2N6O6S2
Formula Weight
571.49
MOL File
123171-59-5.mol
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Cefepime hydrochloride Property

Melting point:
150°C (dec.)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Soluble in DMSO
form 
powder
color 
white to faint yellow
Sensitive 
Light Sensitive
Major Application
pharmaceutical (small molecule)
InChIKey
LRAJHPGSGBRUJN-ZVMPLFRQNA-N
SMILES
C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)C[N+]1(CCCC1)C)(=O)O.[Cl-].Cl.O |&1:5,7,r|
CAS DataBase Reference
123171-59-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-42/43
Safety Statements 
22-26-36/37/39
WGK Germany 
3
HS Code 
29419000
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P284Wear respiratory protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000634
Product name
Cefepime dihydrochloride monohydrate for system suitability
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
15 mg
Price
$165
Updated
2025/07/31
Sigma-Aldrich
Product number
Y0000633
Product name
Cefepime dihydrochloride monohydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
160 mg
Price
$236
Updated
2025/07/31
Sigma-Aldrich
Product number
A3737
Product name
Cefepime hydrochloride
Purity
≥98% (HPLC)
Packaging
100mg
Price
$648
Updated
2025/07/31
Sigma-Aldrich
Product number
1097636
Product name
Cefepime hydrochloride
Packaging
500mg
Price
$410
Updated
2025/07/31
Cayman Chemical
Product number
23633
Product name
Cefepime (hydrochloride hydrate)
Purity
≥90%
Packaging
250mg
Price
$36
Updated
2024/03/01
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Cefepime hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to pale yellow powder

Uses

antipsoriatic, protein synthesis inhibitor

Uses

Cefepime hydrochloride monohydrate is used as a broad spectrum antibiotic targeting a wide variety of naturally antibiotic resistant Gram-positive and Gram-negative bacteria. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases.

Uses

Semisynthetic, fourth generation cephalosporin antibiotic. Antibacterial

Definition

ChEBI: A hydrochloride that is the monohydrate of the dihydrochloride salt of cefepime.

Synthesis

At room temperature (15-25C), 171g of sodium isocaproate (1.03 mol) was dissolved in 900mL of water and 200mL of acetone, and 300g of cefepime sulfate (0.52 mol, weight by weight in anhydrous) was added in batches with effective stirring to form a well-flowing slurry system. 1600mL of acetone and an appropriate amount of activated charcoal were added after 10 minutes and stirred for 30 minutes. The solid was separated by centrifugation or diafiltration. The filter cake was washed with 500 mL of a mixed acetone-water 2:1 (v/v) solution and the filtrates were combined. 18% HCl was added to the filtrate with stirring to pH 1.0 to 1.5. 8 L of acetone was then added over 1 hr. The system was cooled down again to 5 to 10C and stirring was continued for 1 hr. Filter extraction. The filter cake was washed with acetone and dried under vacuum at 40C to give about 270 g of white crystalline powder. Purity 99.7%, water content 3.8% (K-F method), acetone residue 0.25%. The product is cefepime dichlorohydrate monohydrate, i.e. cefepime hydrochloride. All quality indicators meet the requirements of the U.S. Pharmacopeia.

Cefepime hydrochloride Preparation Products And Raw materials

Raw materials

Tylosin

Preparation Products

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Cefepime hydrochloride Suppliers

Austria 1 Canada 1 China 255 Europe 1 France 1 Germany 3 India 23 Italy 1 Poland 2 Singapore 1 Slovenia 1 South Korea 5 Switzerland 1 United Kingdom 11 United States 34 Global 341
Jinan Yunding Biotechnology Co., Ltd
Tel
15662712965
Email
1013429786@qq.com
Country
China
ProdList
26
Advantage
58
Wuhan Dingxintong Pharmaceutical Co. , Ltd.
Tel
027-83984790 17720532645
Email
3489493864@qq.com
Country
China
ProdList
1000
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9411
Advantage
55
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
11776
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777;
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15724
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
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View Lastest Price from Cefepime hydrochloride manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Cefepime Hydrochloride 123171-59-5
Price
US $0.00/Kg
Min. Order
1Kg
Purity
99%
Supply Ability
10kg
Release date
2024-04-09
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
cefepime dihydrochloride hydrate 123171-59-5
Price
US $13.99/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2021-12-23
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
cefepime dihydrochloride hydrate 123171-59-5
Price
US $19.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20kgs
Release date
2022-01-10

123171-59-5, Cefepime hydrochlorideRelated Search:

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  • 123171-59-5
  • C20H29Cl2N5O6S2
  • C19H24N6O5S2xHCl
  • C19H27ClN6O6S2
  • C19H25ClN6O5S2HClH2O
  • C19H28Cl2N6O6S2
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Heterocyclic Compounds