Chloropyramine
- Product Name
- Chloropyramine
- CAS No.
- 59-32-5
- Chemical Name
- Chloropyramine
- Synonyms
- Allergan;Synpen;Avapena;Synopen;synopenr;allergans;Suprastin;Synopen R;Allergan S;Anaphylline
- CBNumber
- CB5327911
- Molecular Formula
- C16H20ClN3
- Formula Weight
- 289.8
- MOL File
- 59-32-5.mol
Chloropyramine Property
- Melting point:
- 25°C
- Boiling point:
- bp0.2 154-155°
- Density
- 1.1031 (rough estimate)
- refractive index
- 1.6010 (estimate)
- pka
- 9.00±0.28(Predicted)
- NIST Chemistry Reference
- Chloropyramine(59-32-5)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- FC164737
- Product name
- Chloropyramine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FC164737
- Product name
- Chloropyramine
- Packaging
- 2g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- FC164737
- Product name
- Chloropyramine
- Packaging
- 5G
- Price
- $325
- Updated
- 2021/12/16
- Product number
- HCH0102862
- Product name
- CHLOROPYRAMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.29
- Updated
- 2021/12/16
Chloropyramine Chemical Properties,Usage,Production
Uses
Chloropyramine is used for allergic dermatosis, allergic rhinitis and conjunctivitis, for drug-induced allergies, in the beginning stages of bronchial asthma, eczema, neurodermatitis, contact dermatitis, and toxicodermia. It also exhibits a sedative effect. Synonyms of this drug are suprastin, chlortripelenamine, and synopen.
Definition
ChEBI: N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridinyl)ethane-1,2-diamine is an aminopyridine.
Synthesis
Chloropyramine, N-(4-chlorobenzyl)-N??,N??-dimethyl-N-2-pyridylethylenediamine (16.1.9), is synthesized in a somewhat different manner, which is by reacting 2-brompyridine with N-(4-chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8). N-(4-Chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8), in turn, is synthesized by condensation of 4-chlorobenzaldehyde c N,N-dimethylethylenediamine with subsequent reduction of the imine group.
in vivo
Chloropyramine (i.p.; 10 mg/kg) abolishes hypothermia in rats[2].
| Animal Model: | Rats[2] |
| Dosage: | 10 mg/kg |
| Administration: | Intraperitoneal |
| Result: | Reduced histamine-induced hypothermia. |
IC 50
H1 Receptor
Chloropyramine Preparation Products And Raw materials
Raw materials
Preparation Products
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