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pheneticillin

Product Name
pheneticillin
CAS No.
147-55-7
Chemical Name
pheneticillin
Synonyms
Penorale;Alfacilin;Synthepen;NSC 117548;Phenoxy PC;Feneticillin;pheneticillin;Phenethecillin;Phenoxyethylpenicillin;pheneticillin USP/EP/BP
CBNumber
CB8897291
Molecular Formula
C17H20N2O5S
Formula Weight
364.42
MOL File
147-55-7.mol
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pheneticillin Property

Boiling point:
673.9±55.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
pka
2.44±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0024890
Product name
PHENETHICILLIN
Purity
95.00%
Packaging
5MG
Price
$502.47
Updated
2021/12/16
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pheneticillin Chemical Properties,Usage,Production

Originator

Syncillin, Bristol, US ,1959

Uses

Phenethicillin is a penicillin antibiotic medication.

Definition

ChEBI: A penicillin in which the substituent at position 6 of the penam ring is a 2-phenoxypropanamido group.

Manufacturing Process

Triethylamine (1.5 ml) was added to a cold solution (10°C) of αphenoxypropionic acid (1.66 g, 0.01 mol) in 15 ml of pure dioxane, with stirring and cooling to 5°C to 10°C while isobutyl chloroformate (1.36 g, 0.01 mol) in 5 ml of dioxane was added dropwise. Then the mixture was stirred for ten minutes at 5°C to 8°C. A solution of 6-amino-penicillanic acid (2.16 g, 0.01 mol) in 15 ml of water and 2 ml of triethylamine was then added dropwise while the temperature was maintained below 10°C. The resulting mixture was stirred in the cold for 15 minutes then at room temperature for 30 minutes, diluted with 30 ml of cold water and extracted with ether which was discarded. The cold aqueous solution was then covered with 75 ml of ether and acidified to pH 2 with 5 N H2SO4. After shaking, the ether layer containing the product 6-(α-phenoxypropionamido)penicillanic acid, was dried for ten minutes over anhydrous sodium sulfate and filtered. Addition of 6 ml of dry n-butanol containing 0.373 g/ml of potassium 2-ethylhexanoate precipitated the potassium salt of the product as a colorless oil which crystallized on stirring and scratching and was collected, dried in vacuo and found to weigh 2.75 g, to melt at 217°C to 219°C.

brand name

Chemipen (Bristol-Myers Squibb); Syncillin (Bristol-Myers Squibb) [Name previously used: Phenethicillin.].

Therapeutic Function

Antibacterial

pheneticillin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from pheneticillin manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Phenethicillin 147-55-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-05-11
Dideu Industries Group Limited
Product
pheneticillin 147-55-7
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-25

147-55-7, pheneticillin Related Search:


  • pheneticillin
  • (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxypropionyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 6α-[(1-Oxo-2-phenoxypropyl)amino]penicillanic acid
  • 1-Phenoxyethylpenicillin
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenoxypropionamido)- (7CI, 8CI)
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenoxypropyl)amino]-, (2S,5R,6R)- (9CI)
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenoxypropyl)amino]-, [2S-(2a,5a,6b)]-
  • Alfacilin
  • a-Phenoxyethylpenicillin
  • Feneticillin
  • NSC 117548
  • Penorale
  • Phenoxy PC
  • Phenoxyethylpenicillin
  • Synthepen
  • Phenethecillin
  • Phenethicillin solution,100ppm
  • Phenethicillin Solution, 600ppm
  • pheneticillin USP/EP/BP
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenoxypropyl)amino]-, (2S,5R,6R)-
  • 147-55-7
  • C17H20N2O5S