ectylurea
- Product Name
- ectylurea
- CAS No.
- 95-04-5
- Chemical Name
- ectylurea
- Synonyms
- Astyn;A18285;Nastyn;Levanil;Sedarex;ectylurea;Ectylcarbamide;2-Ethylcrotonylurea;ectylurea USP/EP/BP;2-Ethyl-cis-crotonylurea
- CBNumber
- CB8898708
- Molecular Formula
- C7H12N2O2
- Formula Weight
- 156.18
- MOL File
- 95-04-5.mol
ectylurea Property
- Melting point:
- 198°, also reported as mp 191-193° (lower melting form, mp 158°)
- Boiling point:
- 280.42°C (rough estimate)
- Density
- 1.1832 (rough estimate)
- refractive index
- 1.4880 (estimate)
- pka
- 11.63±0.46(Predicted)
Safety
- Toxicity
- LD50 in rats (mg/kg): 2500 orally; 900 i.p. (Pindell)
N-Bromosuccinimide Price
- Product number
- API0011059
- Product name
- CIS-2-ETHYLCROTONYLUREA
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.88
- Updated
- 2021/12/16
ectylurea Chemical Properties,Usage,Production
Originator
Nostyn,Ames,US,1956
Definition
ChEBI: Ectylurea is a N-acylurea.
Manufacturing Process
54 g of carbromal (2-bromo-2-ethylbutyryl-urea) in 600 cc of isopropanol was stirred and refluxed for 3 hours with 27.8 g of anhydrous silver oxide. The reaction mixture was filtered and the silver residue was extracted with 100 cc of boiling isopropanol. The filtered and dried solids which separated weighed 22.5 g and melted at 189°C to 190.5°C. Concentration of the filtrate yielded an additional 3.3 g of product which melted at 160°C to 170°C. These two crops were separately obtained as white needles by crystallization from alcohol and exhibited slight solubility in water. The first crop gave 21.7 g of 2- ethyl-cis-crotonyl urea with a melting point of 191°C to 193°C, and the second crop gave 0.9 g with a melting point of 191°C to 193°C for a total yield of 42.4 g or 63% of the theoretical.
Therapeutic Function
Sedative
ectylurea Preparation Products And Raw materials
Raw materials
Preparation Products
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